CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 16 atoms

39 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
39
With full pages
20
Scaffold SMILES

O=c1c2ccsc2ncn1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c2ccsc2ncn1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

5,6-Dimethyl-2-methylsulfanyl-3-phenylthieno[2,3-d]pyrimidin-4-one chemical structure, C15H14N2OS2, CAS 340974-52-9
5,6-Dimethyl-2-methylsulfanyl-3-phenylthieno[2,3-d]pyrimidin-4-one
CAS 340974-52-9C15H14N2OS2
5,6-Dimethyl-2-(2-methylprop-2-enylsulfanyl)-3-phenylthieno[2,3-d]pyrimidin-4-one chemical structure, C18H18N2OS2, CAS 330835-50-2
5,6-Dimethyl-2-(2-methylprop-2-enylsulfanyl)-3-phenylthieno[2,3-d]pyrimidin-4-one
CAS 330835-50-2C18H18N2OS2
6-Ethyl-3-phenylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C14H12N2OS, CAS 312946-72-8
6-Ethyl-3-phenylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 312946-72-8C14H12N2OS
6-Ethyl-3-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-one chemical structure, C15H14N2OS, CAS 312946-73-9
6-Ethyl-3-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-one
CAS 312946-73-9C15H14N2OS
3-(4-Bromophenyl)-6-ethylthieno[2,3-d]pyrimidin-4-one chemical structure, C14H11BrN2OS, CAS 312946-74-0
3-(4-Bromophenyl)-6-ethylthieno[2,3-d]pyrimidin-4-one
CAS 312946-74-0C14H11BrN2OS
3-(4-Chlorophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-one chemical structure, C14H11ClN2OS, CAS 328548-75-0
3-(4-Chlorophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-one
CAS 328548-75-0C14H11ClN2OS
Thieno[2,3-d]pyrimidin-4(3H)-one, 5,6-dimethyl-3-phenyl- chemical structure, C14H12N2OS, CAS 90699-81-3
Thieno[2,3-d]pyrimidin-4(3H)-one, 5,6-dimethyl-3-phenyl-
CAS 90699-81-3C14H12N2OS
3-(2-Methoxyphenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-one chemical structure, C15H14N2O2S, CAS 372496-38-3
3-(2-Methoxyphenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-one
CAS 372496-38-3C15H14N2O2S
3-(4-Methoxyphenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-one chemical structure, C15H14N2O2S, CAS 99379-88-1
3-(4-Methoxyphenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-one
CAS 99379-88-1C15H14N2O2S
2-Ethylsulfanyl-5,6-dimethyl-3-phenylthieno[2,3-d]pyrimidin-4-one chemical structure, C16H16N2OS2, CAS 364742-85-8
2-Ethylsulfanyl-5,6-dimethyl-3-phenylthieno[2,3-d]pyrimidin-4-one
CAS 364742-85-8C16H16N2OS2
5,6-Dimethyl-3-(4-methylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C15H14N2OS, CAS 32973-76-5
5,6-Dimethyl-3-(4-methylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one
CAS 32973-76-5C15H14N2OS
3-(3-Methoxyphenyl)-6-methylthieno[2,3-d]pyrimidin-4-one chemical structure, C14H12N2O2S, CAS 446870-48-0
3-(3-Methoxyphenyl)-6-methylthieno[2,3-d]pyrimidin-4-one
CAS 446870-48-0C14H12N2O2S
2-Methyl-3-(2-methylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C14H12N2OS, CAS 22288-90-0
2-Methyl-3-(2-methylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one
CAS 22288-90-0C14H12N2OS
2-Methyl-3-(3-methylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C14H12N2OS, CAS 22288-91-1
2-Methyl-3-(3-methylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one
CAS 22288-91-1C14H12N2OS
5,6-Dimethyl-3-(3-methylphenyl)thieno[2,3-d]pyrimidin-4-one chemical structure, C15H14N2OS, CAS 634593-52-5
5,6-Dimethyl-3-(3-methylphenyl)thieno[2,3-d]pyrimidin-4-one
CAS 634593-52-5C15H14N2OS
2-((6-Ethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetic acid chemical structure, C16H14N2O3S2, CAS 406199-75-5
2-((6-Ethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetic acid
CAS 406199-75-5C16H14N2O3S2
tert-Butyl [(5,6-dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetate chemical structure, C20H22N2O3S2, CAS 379256-68-5
tert-Butyl [(5,6-dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetate
CAS 379256-68-5C20H22N2O3S2
3-(4-Iodophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-one chemical structure, C14H11IN2OS, CAS 312946-71-7
3-(4-Iodophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-one
CAS 312946-71-7C14H11IN2OS
2-[3-(3,4-Dichlorophenyl)-5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanylacetamide chemical structure, C16H13Cl2N3O2S2, CAS 380453-34-9
2-[3-(3,4-Dichlorophenyl)-5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanylacetamide
CAS 380453-34-9C16H13Cl2N3O2S2
3-(4-Methoxyphenyl)thieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C13H10N2O2S, CAS 338750-50-8
3-(4-Methoxyphenyl)thieno[2,3-d]pyrimidin-4(3H)-one
CAS 338750-50-8C13H10N2O2S
2-[(5,6-Dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N,N-dimethylacetamide chemical structure, C18H19N3O2S2, CAS 496027-35-1
2-[(5,6-Dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N,N-dimethylacetamide
CAS 496027-35-1C18H19N3O2S2
2-((5,6-Dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)-N-(2-methoxyethyl)acetamide chemical structure, C19H21N3O3S2, CAS 457952-15-7
2-((5,6-Dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)-N-(2-methoxyethyl)acetamide
CAS 457952-15-7C19H21N3O3S2
2-((5,6-Dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)-N-(2-hydroxyethyl)acetamide chemical structure, C18H19N3O3S2, CAS 325693-69-4
2-((5,6-Dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)-N-(2-hydroxyethyl)acetamide
CAS 325693-69-4C18H19N3O3S2
Ethyl 4-[(5,6-dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)sulfanyl]butanoate chemical structure, C20H22N2O3S2, CAS 342779-08-2
Ethyl 4-[(5,6-dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)sulfanyl]butanoate
CAS 342779-08-2C20H22N2O3S2