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Murcko scaffold

N-(1,1-Dioxidotetrahydrothiophen-3-yl)benzamide scaffold

204 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
204
With full pages
23
Scaffold SMILES

O=C(NC1CCS(=O)(=O)C1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(1,1-Dioxidotetrahydrothiophen-3-yl)benzamide page
Murcko scaffold O=C(NC1CCS(=O)(=O)C1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 204 chemicals

N-(1,1-Dioxothiolan-3-yl)-4-propan-2-yloxybenzamide chemical structure, C14H19NO4S, CAS 505067-65-2
N-(1,1-Dioxothiolan-3-yl)-4-propan-2-yloxybenzamide
CAS 505067-65-2C14H19NO4S
4-Chloro-N-(1,1-dioxothiolan-3-yl)-N-methyl-3-nitrobenzamide chemical structure, C12H13ClN2O5S, CAS 314768-48-4
4-Chloro-N-(1,1-dioxothiolan-3-yl)-N-methyl-3-nitrobenzamide
CAS 314768-48-4C12H13ClN2O5S
4-Bromo-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide chemical structure, C11H12BrNO3S, CAS 303016-16-2
4-Bromo-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide
CAS 303016-16-2C11H12BrNO3S
N-(1,1-Dioxothiolan-3-yl)-4-methoxybenzamide chemical structure, C12H15NO4S, CAS 688002-41-7
N-(1,1-Dioxothiolan-3-yl)-4-methoxybenzamide
CAS 688002-41-7C12H15NO4S
4-tert-Butyl-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide chemical structure, C15H21NO3S, CAS 324070-99-7
4-tert-Butyl-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide
CAS 324070-99-7C15H21NO3S
4-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide chemical structure, C11H12ClNO3S, CAS 314046-01-0
4-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide
CAS 314046-01-0C11H12ClNO3S
N-(1,1-Dioxothiolan-3-yl)-4-nitrobenzamide chemical structure, C11H12N2O5S, CAS 303016-15-1
N-(1,1-Dioxothiolan-3-yl)-4-nitrobenzamide
CAS 303016-15-1C11H12N2O5S
N-(1,1-Dioxothiolan-3-yl)-3-nitrobenzamide chemical structure, C11H12N2O5S, CAS 303015-88-5
N-(1,1-Dioxothiolan-3-yl)-3-nitrobenzamide
CAS 303015-88-5C11H12N2O5S
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-4-methylbenzamide chemical structure, C12H15NO3S, CAS 314045-77-7
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-4-methylbenzamide
CAS 314045-77-7C12H15NO3S
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-3,4,5-trimethoxybenzamide chemical structure, C14H19NO6S, CAS 314768-59-7
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-3,4,5-trimethoxybenzamide
CAS 314768-59-7C14H19NO6S
N-(1,1-Dioxidotetrahydro-3-thienyl)-3-nitro-N-methyl-4-(methylamino)benzamide chemical structure, C13H17N3O5S, CAS 371209-00-6
N-(1,1-Dioxidotetrahydro-3-thienyl)-3-nitro-N-methyl-4-(methylamino)benzamide
CAS 371209-00-6C13H17N3O5S
N-(1,1-Dioxidotetrahydrothiophen-3-yl)benzamide chemical structure, C11H13NO3S, CAS 17153-58-1
N-(1,1-Dioxidotetrahydrothiophen-3-yl)benzamide
CAS 17153-58-1C11H13NO3S
2-Bromo-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide chemical structure, C11H12BrNO3S, CAS 303016-10-6
2-Bromo-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide
CAS 303016-10-6C11H12BrNO3S
N-(1,1-Dioxothiolan-3-yl)-4-propoxybenzamide chemical structure, C14H19NO4S, CAS 608492-82-6
N-(1,1-Dioxothiolan-3-yl)-4-propoxybenzamide
CAS 608492-82-6C14H19NO4S
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-4-(2-methylpropoxy)benzamide chemical structure, C15H21NO4S, CAS 460044-79-5
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-4-(2-methylpropoxy)benzamide
CAS 460044-79-5C15H21NO4S
N-(1,1-Dioxothiolan-3-yl)-2-methoxybenzamide chemical structure, C12H15NO4S, CAS 462069-23-4
N-(1,1-Dioxothiolan-3-yl)-2-methoxybenzamide
CAS 462069-23-4C12H15NO4S
4-Cyano-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide chemical structure, C12H12N2O3S, CAS 616214-33-6
4-Cyano-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide
CAS 616214-33-6C12H12N2O3S
N-(1,1-Dioxothiolan-3-yl)-2-methylbenzamide chemical structure, C12H15NO3S, CAS 615273-75-1
N-(1,1-Dioxothiolan-3-yl)-2-methylbenzamide
CAS 615273-75-1C12H15NO3S
N-(1,1-Dioxothiolan-3-yl)-3,4-dimethoxybenzamide chemical structure, C13H17NO5S, CAS 620590-29-6
N-(1,1-Dioxothiolan-3-yl)-3,4-dimethoxybenzamide
CAS 620590-29-6C13H17NO5S
N,4-dimethyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide chemical structure, C14H19NO3S, CAS 694502-06-2
N,4-dimethyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide
CAS 694502-06-2C14H19NO3S
N-(1,1-Dioxothiolan-3-yl)-4-ethoxy-N-methylbenzamide chemical structure, C14H19NO4S, CAS 694515-25-8
N-(1,1-Dioxothiolan-3-yl)-4-ethoxy-N-methylbenzamide
CAS 694515-25-8C14H19NO4S
N-(1,1-Dioxothiolan-3-yl)-4-iodobenzamide chemical structure, C11H12INO3S, CAS 620590-28-5
N-(1,1-Dioxothiolan-3-yl)-4-iodobenzamide
CAS 620590-28-5C11H12INO3S
N-(1,1-Dioxothiolan-3-yl)-3-methoxybenzamide chemical structure, C12H15NO4S, CAS 710985-66-3
N-(1,1-Dioxothiolan-3-yl)-3-methoxybenzamide
CAS 710985-66-3C12H15NO4S
N-Methyl-N-(3-methyl-1,1-dioxidotetrahydro-3-thienyl)benzamide chemical structure, C13H17NO3S, CAS 712282-06-9
N-Methyl-N-(3-methyl-1,1-dioxidotetrahydro-3-thienyl)benzamide
CAS 712282-06-9C13H17NO3S