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Murcko scaffold

N-(1,1-Dioxidotetrahydrothiophen-3-yl)benzamide scaffold

204 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
204
With full pages
23
Scaffold SMILES

O=C(NC1CCS(=O)(=O)C1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(1,1-Dioxidotetrahydrothiophen-3-yl)benzamide page
Murcko scaffold O=C(NC1CCS(=O)(=O)C1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 204 chemicals

4-Ethoxy-N-methyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide chemical structure, C15H21NO4S, CAS 874594-60-2
4-Ethoxy-N-methyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide
CAS 874594-60-2C15H21NO4S
N,4-dimethyl-N-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)-3-nitrobenzamide chemical structure, C14H18N2O5S, CAS 874594-62-4
N,4-dimethyl-N-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)-3-nitrobenzamide
CAS 874594-62-4C14H18N2O5S
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-4-methyl-3-nitrobenzamide chemical structure, C12H14N2O5S, CAS 874788-56-4
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-4-methyl-3-nitrobenzamide
CAS 874788-56-4C12H14N2O5S
3,4-Dimethoxy-N-methyl-N-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)benzamide chemical structure, C15H21NO5S, CAS 874788-59-7
3,4-Dimethoxy-N-methyl-N-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)benzamide
CAS 874788-59-7C15H21NO5S
4-tert-Butyl-N-methyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide chemical structure, C17H25NO3S, CAS 874788-63-3
4-tert-Butyl-N-methyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide
CAS 874788-63-3C17H25NO3S
N,3,4-trimethyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide chemical structure, C15H21NO3S, CAS 874788-65-5
N,3,4-trimethyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide
CAS 874788-65-5C15H21NO3S
4-Chloro-N-methyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)-3-nitrobenzamide chemical structure, C13H15ClN2O5S, CAS 874788-67-7
4-Chloro-N-methyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)-3-nitrobenzamide
CAS 874788-67-7C13H15ClN2O5S
3,4,5-Trimethoxy-N-methyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide chemical structure, C16H23NO6S, CAS 874651-89-5
3,4,5-Trimethoxy-N-methyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide
CAS 874651-89-5C16H23NO6S
N,3,5-trimethyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide chemical structure, C15H21NO3S, CAS 874651-90-8
N,3,5-trimethyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide
CAS 874651-90-8C15H21NO3S
3,5-Dimethoxy-N-methyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide chemical structure, C15H21NO5S, CAS 874651-91-9
3,5-Dimethoxy-N-methyl-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)benzamide
CAS 874651-91-9C15H21NO5S
N-Methyl-N-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)-4-nitrobenzamide chemical structure, C13H16N2O5S, CAS 874651-92-0
N-Methyl-N-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)-4-nitrobenzamide
CAS 874651-92-0C13H16N2O5S
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-N-methyl-3-nitrobenzamide chemical structure, C12H14N2O5S, CAS 874651-93-1
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-N-methyl-3-nitrobenzamide
CAS 874651-93-1C12H14N2O5S
4-Bromo-N-(1,1-dioxo-1lambda6-thiolan-3-yl)-N-ethylbenzamide chemical structure, C13H16BrNO3S, CAS 874787-62-9
4-Bromo-N-(1,1-dioxo-1lambda6-thiolan-3-yl)-N-ethylbenzamide
CAS 874787-62-9C13H16BrNO3S
4-Bromo-N-butyl-N-(1,1-dioxo-1lambda6-thiolan-3-yl)benzamide chemical structure, C15H20BrNO3S, CAS 874787-66-3
4-Bromo-N-butyl-N-(1,1-dioxo-1lambda6-thiolan-3-yl)benzamide
CAS 874787-66-3C15H20BrNO3S
N-Butyl-N-(1,1-dioxidotetrahydrothiophen-3-yl)-4-methyl-3-nitrobenzamide chemical structure, C16H22N2O5S, CAS 874787-69-6
N-Butyl-N-(1,1-dioxidotetrahydrothiophen-3-yl)-4-methyl-3-nitrobenzamide
CAS 874787-69-6C16H22N2O5S
4-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-isobutyl-3-nitrobenzamide chemical structure, C15H19ClN2O5S, CAS 874787-74-3
4-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-isobutyl-3-nitrobenzamide
CAS 874787-74-3C15H19ClN2O5S
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-N-(2-methylpropyl)-4-(propan-2-yloxy)benzamide chemical structure, C18H27NO4S, CAS 874787-79-8
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-N-(2-methylpropyl)-4-(propan-2-yloxy)benzamide
CAS 874787-79-8C18H27NO4S
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-N-ethyl-4-(propan-2-yloxy)benzamide chemical structure, C16H23NO4S, CAS 874787-80-1
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-N-ethyl-4-(propan-2-yloxy)benzamide
CAS 874787-80-1C16H23NO4S
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N,4-dimethyl-3-nitrobenzamide chemical structure, C13H16N2O5S, CAS 874788-22-4
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N,4-dimethyl-3-nitrobenzamide
CAS 874788-22-4C13H16N2O5S
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-3,4-dimethoxy-N-methylbenzamide chemical structure, C14H19NO5S, CAS 874788-23-5
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-3,4-dimethoxy-N-methylbenzamide
CAS 874788-23-5C14H19NO5S
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-2-ethoxybenzamide chemical structure, C13H17NO4S, CAS 874788-24-6
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-2-ethoxybenzamide
CAS 874788-24-6C13H17NO4S
3-(N,N-Dimethylsulfamoyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide chemical structure, C13H18N2O5S2, CAS 874788-25-7
3-(N,N-Dimethylsulfamoyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide
CAS 874788-25-7C13H18N2O5S2
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-4-fluorobenzamide chemical structure, C11H12FNO3S, CAS 874788-26-8
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-4-fluorobenzamide
CAS 874788-26-8C11H12FNO3S
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-N-(2-methylpropyl)-3-(trifluoromethyl)benzamide chemical structure, C16H20F3NO3S, CAS 874788-29-1
N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-N-(2-methylpropyl)-3-(trifluoromethyl)benzamide
CAS 874788-29-1C16H20F3NO3S