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Murcko scaffold

1-(1H-Imidazol-2-yl)piperazine scaffold

29 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
29
With full pages
3
Scaffold SMILES

c1c[nH]c(N2CCNCC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(1H-Imidazol-2-yl)piperazine page
Murcko scaffold c1c[nH]c(N2CCNCC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

1-[4-(1-Methyl-1H-imidazol-2-yl)piperazin-1-yl]ethan-1-one chemical structure, C10H16N4O, CAS 85671-89-2
1-[4-(1-Methyl-1H-imidazol-2-yl)piperazin-1-yl]ethan-1-one
CAS 85671-89-2C10H16N4O
1-(1-Methyl-1H-imidazol-2-yl)piperazine chemical structure, C8H14N4, CAS 113049-35-7
1-(1-Methyl-1H-imidazol-2-yl)piperazine
CAS 113049-35-7C8H14N4
1-(1H-Imidazol-2-yl)piperazine chemical structure, C7H12N4, CAS 902770-91-6
1-(1H-Imidazol-2-yl)piperazine
CAS 902770-91-6C7H12N4
1-(4-(1-Ethyl-1H-imidazol-2-yl)piperazin-1-yl)-2-propylpentan-1-one hydrochloride chemical structure, C17H31ClN4O, CAS 1189861-81-1
1-(4-(1-Ethyl-1H-imidazol-2-yl)piperazin-1-yl)-2-propylpentan-1-one hydrochloride
CAS 1189861-81-1C17H31ClN4O
2-Ethoxy-1-(4-(1-ethyl-1H-imidazol-2-yl)piperazin-1-yl)ethanone hydrochloride chemical structure, C13H23ClN4O2, CAS 1185119-12-3
2-Ethoxy-1-(4-(1-ethyl-1H-imidazol-2-yl)piperazin-1-yl)ethanone hydrochloride
CAS 1185119-12-3C13H23ClN4O2
N,N-Diethyl-2-[4-(1-ethyl-1H-imidazol-2-yl)piperazin-1-yl]acetamide dihydrochloride chemical structure, C15H29Cl2N5O, CAS 1323621-75-5
N,N-Diethyl-2-[4-(1-ethyl-1H-imidazol-2-yl)piperazin-1-yl]acetamide dihydrochloride
CAS 1323621-75-5C15H29Cl2N5O
2-(4-(1-Ethyl-1H-imidazol-2-yl)piperazin-1-yl)-N-isopropylacetamide dihydrochloride chemical structure, C14H27Cl2N5O, CAS 1331266-22-8
2-(4-(1-Ethyl-1H-imidazol-2-yl)piperazin-1-yl)-N-isopropylacetamide dihydrochloride
CAS 1331266-22-8C14H27Cl2N5O
1-(1-Ethyl-1H-imidazol-2-yl)-piperazine chemical structure, C9H16N4, CAS 1019115-40-2
1-(1-Ethyl-1H-imidazol-2-yl)-piperazine
CAS 1019115-40-2C9H16N4
1-(1-Methyl-1H-imidazol-2-yl)piperazine hydrochloride chemical structure, C8H15ClN4, CAS 1334147-53-3
1-(1-Methyl-1H-imidazol-2-yl)piperazine hydrochloride
CAS 1334147-53-3C8H15ClN4
1-(4,5-Dibromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-2-yl)piperazine chemical structure, C13H24Br2N4OSi, CAS 883876-48-0
1-(4,5-Dibromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-2-yl)piperazine
CAS 883876-48-0C13H24Br2N4OSi
1-(1-Methyl-1H-imidazol-2-yl)piperazine dihydrochloride chemical structure, C8H16Cl2N4, CAS 1394041-47-4
1-(1-Methyl-1H-imidazol-2-yl)piperazine dihydrochloride
CAS 1394041-47-4C8H16Cl2N4
1-(1-Ethyl-1H-imidazol-2-yl)piperazine dihydrochloride chemical structure, C9H18Cl2N4, CAS 1216433-63-4
1-(1-Ethyl-1H-imidazol-2-yl)piperazine dihydrochloride
CAS 1216433-63-4C9H18Cl2N4
1-[4-(1-Methyl-1H-imidazol-2-yl)piperazin-1-yl]pentan-1-one hydrochloride chemical structure, C13H23ClN4O, CAS 1189708-95-9
1-[4-(1-Methyl-1H-imidazol-2-yl)piperazin-1-yl]pentan-1-one hydrochloride
CAS 1189708-95-9C13H23ClN4O
1-[4-(1-Ethyl-1H-imidazol-2-yl)piperazin-1-yl]-3,3-dimethylbutan-1-one hydrochloride chemical structure, C15H27ClN4O, CAS 1323291-05-9
1-[4-(1-Ethyl-1H-imidazol-2-yl)piperazin-1-yl]-3,3-dimethylbutan-1-one hydrochloride
CAS 1323291-05-9C15H27ClN4O
2-(4-(1-Ethyl-1H-imidazol-2-yl)piperazin-1-yl)-N-(2-methoxyethyl)acetamide dihydrochloride chemical structure, C14H27Cl2N5O2, CAS 1351610-66-6
2-(4-(1-Ethyl-1H-imidazol-2-yl)piperazin-1-yl)-N-(2-methoxyethyl)acetamide dihydrochloride
CAS 1351610-66-6C14H27Cl2N5O2
4-Bromo-2-(piperazin-1-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-5-carboxylic acid chemical structure, C14H25BrN4O3Si, CAS 1359655-53-0
4-Bromo-2-(piperazin-1-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-5-carboxylic acid
CAS 1359655-53-0C14H25BrN4O3Si
2-(1-Piperazinyl)-1H-imidazole-5-carboxaldehyde chemical structure, C8H12N4O, CAS 1780347-41-2
2-(1-Piperazinyl)-1H-imidazole-5-carboxaldehyde
CAS 1780347-41-2C8H12N4O
1-(1,5-Dimethyl-1H-imidazol-2-yl)piperazine chemical structure, C9H16N4, CAS 1534648-35-5
1-(1,5-Dimethyl-1H-imidazol-2-yl)piperazine
CAS 1534648-35-5C9H16N4
1-(1H-Imidazol-2-yl)piperazine dihydrochloride chemical structure, C7H14Cl2N4, CAS 1795503-50-2
1-(1H-Imidazol-2-yl)piperazine dihydrochloride
CAS 1795503-50-2C7H14Cl2N4
1-(4-Bromo-1-methyl-1H-imidazol-2-yl)piperazine chemical structure, C8H13BrN4, CAS 1776066-53-5
1-(4-Bromo-1-methyl-1H-imidazol-2-yl)piperazine
CAS 1776066-53-5C8H13BrN4
1-(4-Bromo-1-methyl-1H-imidazol-2-yl)-4-methylpiperazine chemical structure, C9H15BrN4, CAS 1894326-21-6
1-(4-Bromo-1-methyl-1H-imidazol-2-yl)-4-methylpiperazine
CAS 1894326-21-6C9H15BrN4
1-(1,5-Dimethyl-1H-imidazol-2-yl)piperazine dihydrochloride chemical structure, C9H18Cl2N4, CAS 1956380-83-8
1-(1,5-Dimethyl-1H-imidazol-2-yl)piperazine dihydrochloride
CAS 1956380-83-8C9H18Cl2N4
1-(4-(1,5-Dimethyl-1H-imidazol-2-yl)piperazin-1-yl)ethanone chemical structure, C11H18N4O, CAS 1956335-89-9
1-(4-(1,5-Dimethyl-1H-imidazol-2-yl)piperazin-1-yl)ethanone
CAS 1956335-89-9C11H18N4O
1-Isopropyl-4-(1-methyl-1H-imidazol-2-yl)piperazine chemical structure, C11H20N4, CAS 2034286-37-6
1-Isopropyl-4-(1-methyl-1H-imidazol-2-yl)piperazine
CAS 2034286-37-6C11H20N4