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Murcko scaffold

4,8-Bis(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane scaffold

49 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 28
Chemicals: 49
With full pages: 11

Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCC2(CC1)OCCN2S(=O)(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 4,8-Bis(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane page

Murcko scaffold O=S(=O)(c1ccccc1)N1CCC2(CC1)OCCN2S(=O)(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 49 chemicals

8-((2,5-Difluorophenyl)sulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C20H22F2N2O5S2, CAS 898424-95-8

8-((2,5-Difluorophenyl)sulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898424-95-8C₂₀H₂₂F₂N₂O₅S₂

8-(Mesitylsulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C23H30N2O5S2, CAS 898424-97-0

8-(Mesitylsulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898424-97-0C₂₃H₃₀N₂O₅S₂

8-((4-Fluoro-2-methylphenyl)sulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C21H25FN2O5S2, CAS 898408-18-9

8-((4-Fluoro-2-methylphenyl)sulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898408-18-9C₂₁H₂₅FN₂O₅S₂

8-((4-Fluoro-3-methylphenyl)sulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C21H25FN2O5S2, CAS 898452-89-6

8-((4-Fluoro-3-methylphenyl)sulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898452-89-6C₂₁H₂₅FN₂O₅S₂

8-((2,5-Dimethylphenyl)sulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C22H28N2O5S2, CAS 898425-01-9

8-((2,5-Dimethylphenyl)sulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898425-01-9C₂₂H₂₈N₂O₅S₂

8-((5-Fluoro-2-methoxyphenyl)sulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C21H25FN2O6S2, CAS 898425-03-1

8-((5-Fluoro-2-methoxyphenyl)sulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898425-03-1C₂₁H₂₅FN₂O₆S₂

8-((2,5-Difluorophenyl)sulfonyl)-4-((4-methoxyphenyl)sulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C20H22F2N2O6S2, CAS 898452-93-2

8-((2,5-Difluorophenyl)sulfonyl)-4-((4-methoxyphenyl)sulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898452-93-2C₂₀H₂₂F₂N₂O₆S₂

8-((4-Fluoro-2-methylphenyl)sulfonyl)-4-((4-methoxyphenyl)sulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C21H25FN2O6S2, CAS 898408-26-9

8-((4-Fluoro-2-methylphenyl)sulfonyl)-4-((4-methoxyphenyl)sulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898408-26-9C₂₁H₂₅FN₂O₆S₂

8-((4-Fluoro-3-methylphenyl)sulfonyl)-4-((4-methoxyphenyl)sulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C21H25FN2O6S2, CAS 898452-99-8

8-((4-Fluoro-3-methylphenyl)sulfonyl)-4-((4-methoxyphenyl)sulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898452-99-8C₂₁H₂₅FN₂O₆S₂

8-((4-Fluorophenyl)sulfonyl)-4-(mesitylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C22H27FN2O5S2, CAS 898453-01-5

8-((4-Fluorophenyl)sulfonyl)-4-(mesitylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898453-01-5C₂₂H₂₇FN₂O₅S₂

4-(Mesitylsulfonyl)-8-(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C22H28N2O5S2, CAS 898408-30-5

4-(Mesitylsulfonyl)-8-(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898408-30-5C₂₂H₂₈N₂O₅S₂

4-(Mesitylsulfonyl)-8-tosyl-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C23H30N2O5S2, CAS 898453-03-7

4-(Mesitylsulfonyl)-8-tosyl-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898453-03-7C₂₃H₃₀N₂O₅S₂

8-((4-Chlorophenyl)sulfonyl)-4-(mesitylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C22H27ClN2O5S2, CAS 898425-14-4

8-((4-Chlorophenyl)sulfonyl)-4-(mesitylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898425-14-4C₂₂H₂₇ClN₂O₅S₂

8-((4-Fluoro-2-methylphenyl)sulfonyl)-4-(mesitylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C23H29FN2O5S2, CAS 898408-32-7

8-((4-Fluoro-2-methylphenyl)sulfonyl)-4-(mesitylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898408-32-7C₂₃H₂₉FN₂O₅S₂

8-((4-Fluoro-3-methylphenyl)sulfonyl)-4-(mesitylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C23H29FN2O5S2, CAS 898453-05-9

8-((4-Fluoro-3-methylphenyl)sulfonyl)-4-(mesitylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898453-05-9C₂₃H₂₉FN₂O₅S₂

8-((2,5-Dimethylphenyl)sulfonyl)-4-(mesitylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C24H32N2O5S2, CAS 898425-16-6

8-((2,5-Dimethylphenyl)sulfonyl)-4-(mesitylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898425-16-6C₂₄H₃₂N₂O₅S₂

8-((2,5-Difluorophenyl)sulfonyl)-4-(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C19H20F2N2O5S2, CAS 898453-07-1

8-((2,5-Difluorophenyl)sulfonyl)-4-(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898453-07-1C₁₉H₂₀F₂N₂O₅S₂

8-(Mesitylsulfonyl)-4-(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C22H28N2O5S2, CAS 898453-10-6

8-(Mesitylsulfonyl)-4-(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898453-10-6C₂₂H₂₈N₂O₅S₂

8-((4-Fluoro-3-methylphenyl)sulfonyl)-4-(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C20H23FN2O5S2, CAS 898408-39-4

8-((4-Fluoro-3-methylphenyl)sulfonyl)-4-(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898408-39-4C₂₀H₂₃FN₂O₅S₂

8-((2,5-Dimethylphenyl)sulfonyl)-4-(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C21H26N2O5S2, CAS 898453-14-0

8-((2,5-Dimethylphenyl)sulfonyl)-4-(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898453-14-0C₂₁H₂₆N₂O₅S₂

8-((5-Fluoro-2-methoxyphenyl)sulfonyl)-4-(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C20H23FN2O6S2, CAS 898453-16-2

8-((5-Fluoro-2-methoxyphenyl)sulfonyl)-4-(phenylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898453-16-2C₂₀H₂₃FN₂O₆S₂

8-(Phenylsulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C20H24N2O5S2, CAS 898408-17-8

8-(Phenylsulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898408-17-8C₂₀H₂₄N₂O₅S₂

4-(Phenylsulfonyl)-8-tosyl-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C20H24N2O5S2, CAS 898408-38-3

4-(Phenylsulfonyl)-8-tosyl-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898408-38-3C₂₀H₂₄N₂O₅S₂

8-((3,4-Dimethoxyphenyl)sulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane chemical structure, C22H28N2O7S2, CAS 898408-13-4

8-((3,4-Dimethoxyphenyl)sulfonyl)-4-tosyl-1-oxa-4,8-diazaspiro[4.5]decane

CAS 898408-13-4C₂₂H₂₈N₂O₇S₂