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Murcko scaffold

Ring system with 2 rings and 14 atoms

13 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
13
With full pages
4
Scaffold SMILES

O=C1CC(Sc2ccccc2)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(Sc2ccccc2)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

2-[(2,5-Dioxopyrrolidin-3-yl)thio]benzoic acid chemical structure, C11H9NO4S, CAS 459421-21-7
2-[(2,5-Dioxopyrrolidin-3-yl)thio]benzoic acid
CAS 459421-21-7C11H9NO4S
2-[(1-Ethyl-2,5-dioxopyrrolidin-3-yl)thio]benzoic acid chemical structure, C13H13NO4S, CAS 350030-47-6
2-[(1-Ethyl-2,5-dioxopyrrolidin-3-yl)thio]benzoic acid
CAS 350030-47-6C13H13NO4S
2-((1-(3-Isopropoxypropyl)-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid chemical structure, C17H21NO5S, CAS 857493-93-7
2-((1-(3-Isopropoxypropyl)-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid
CAS 857493-93-7C17H21NO5S
2-((1-Isobutyl-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid chemical structure, C15H17NO4S, CAS 831194-72-0
2-((1-Isobutyl-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid
CAS 831194-72-0C15H17NO4S
2-((1-(2-Methoxyethyl)-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid chemical structure, C14H15NO5S, CAS 831207-85-3
2-((1-(2-Methoxyethyl)-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid
CAS 831207-85-3C14H15NO5S
2-[(2,5-Dioxo-1-propylpyrrolidin-3-yl)sulfanyl]benzoic acid chemical structure, C14H15NO4S, CAS 838867-39-3
2-[(2,5-Dioxo-1-propylpyrrolidin-3-yl)sulfanyl]benzoic acid
CAS 838867-39-3C14H15NO4S
2-((1-Butyl-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid chemical structure, C15H17NO4S, CAS 459421-25-1
2-((1-Butyl-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid
CAS 459421-25-1C15H17NO4S
2-((1-Methyl-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid chemical structure, C12H11NO4S, CAS 132228-17-2
2-((1-Methyl-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid
CAS 132228-17-2C12H11NO4S
2-[(1-Isopropyl-2,5-dioxopyrrolidin-3-yl)thio]benzoic acid chemical structure, C14H15NO4S, CAS 459421-23-9
2-[(1-Isopropyl-2,5-dioxopyrrolidin-3-yl)thio]benzoic acid
CAS 459421-23-9C14H15NO4S
2-((1-(3-Methoxypropyl)-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid chemical structure, C15H17NO5S, CAS 881483-45-0
2-((1-(3-Methoxypropyl)-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid
CAS 881483-45-0C15H17NO5S
2-((1-Allyl-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid chemical structure, C14H13NO4S, CAS 881483-57-4
2-((1-Allyl-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid
CAS 881483-57-4C14H13NO4S
1-Butyl-3-(phenylsulfanyl)pyrrolidine-2,5-dione chemical structure, C14H17NO2S, CAS 62164-00-5
1-Butyl-3-(phenylsulfanyl)pyrrolidine-2,5-dione
CAS 62164-00-5C14H17NO2S
1-Octadecyl-3-[(4-sulfanylphenyl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C28H45NO2S2, CAS 918631-39-7
1-Octadecyl-3-[(4-sulfanylphenyl)sulfanyl]pyrrolidine-2,5-dione
CAS 918631-39-7C28H45NO2S2