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Murcko scaffold

Ring system with 2 rings and 18 atoms

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
18
With full pages
9
Scaffold SMILES

O=S(=O)(C=Cc1ccccc1)Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(C=Cc1ccccc1)Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

Benzene, 1-fluoro-4-[2-[(phenylmethyl)sulfonyl]ethenyl]- chemical structure, C15H13FO2S, CAS 90616-51-6
Benzene, 1-fluoro-4-[2-[(phenylmethyl)sulfonyl]ethenyl]-
CAS 90616-51-6C15H13FO2S
Rigosertib chemical structure, C21H25NO8S, CAS 592542-59-1
Rigosertib
CAS 592542-59-1C21H25NO8S
Recilisib chemical structure, C16H13ClO4S, CAS 334969-03-8
Recilisib
CAS 334969-03-8C16H13ClO4S
N-(2-Methoxy-5-((((1E)-2-(2,4,6-imethoxyphenyl)ethenyl)sulfonyl)methyl)phenyl)-L-alanine chemical structure, C22H27NO8S, CAS 592543-24-3
N-(2-Methoxy-5-((((1E)-2-(2,4,6-imethoxyphenyl)ethenyl)sulfonyl)methyl)phenyl)-L-alanine
CAS 592543-24-3C22H27NO8S
Briciclib chemical structure, C19H23O10PS, CAS 865783-99-9
Briciclib
CAS 865783-99-9C19H23O10PS
ON-013100 chemical structure, C19H22O7S, CAS 865783-95-5
ON-013100
CAS 865783-95-5C19H22O7S
Antitumor agent-60 chemical structure, C24H28O10S, CAS 865784-65-2
Antitumor agent-60
CAS 865784-65-2C24H28O10S
(E)-2-Methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)aniline chemical structure, C19H23NO6S, CAS 592542-50-2
(E)-2-Methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)aniline
CAS 592542-50-2C19H23NO6S
2-[[[2-Methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]amino]sulfonyl]acetic acid chemical structure, C21H25NO10S2, CAS 592542-53-5
2-[[[2-Methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]amino]sulfonyl]acetic acid
CAS 592542-53-5C21H25NO10S2
(E)-2,4,6-Trimethoxystyryl 4-Methoxy-3-Nitrobenzyl sulfone chemical structure, C19H21NO8S, CAS 592542-52-4
(E)-2,4,6-Trimethoxystyryl 4-Methoxy-3-Nitrobenzyl sulfone
CAS 592542-52-4C19H21NO8S
Recilisib sodium chemical structure, C16H12ClNaO4S, CAS 922139-31-9
Recilisib sodium
CAS 922139-31-9C16H12ClNaO4S
Rigosertib sodium chemical structure, C21H24NNaO8S, CAS 592542-60-4
Rigosertib sodium
CAS 592542-60-4C21H24NNaO8S
Briciclib sodium chemical structure, C19H21Na2O10PS, CAS 865784-01-6
Briciclib sodium
CAS 865784-01-6C19H21Na2O10PS
1-Chloro-4-{[2-(4-fluorophenyl)ethenesulfonyl]methyl}benzene chemical structure, C15H12ClFO2S, CAS 118672-28-9
1-Chloro-4-{[2-(4-fluorophenyl)ethenesulfonyl]methyl}benzene
CAS 118672-28-9C15H12ClFO2S
1-Fluoro-4-{2-[(4-nitrophenyl)methanesulfonyl]ethenyl}benzene chemical structure, C15H12FNO4S, CAS 664979-27-5
1-Fluoro-4-{2-[(4-nitrophenyl)methanesulfonyl]ethenyl}benzene
CAS 664979-27-5C15H12FNO4S
1-Chloro-4-{[2-(4-chlorophenyl)ethenesulfonyl]methyl}benzene chemical structure, C15H12Cl2O2S, CAS 118672-29-0
1-Chloro-4-{[2-(4-chlorophenyl)ethenesulfonyl]methyl}benzene
CAS 118672-29-0C15H12Cl2O2S
(E)-Metyl 2-((2-metoxy-5-(((2,4,6-trimetoxystyryl)sulfonyl)metyl)fenyl)amino) acetate chemical structure, C22H27NO8S, CAS 592542-61-5
(E)-Metyl 2-((2-metoxy-5-(((2,4,6-trimetoxystyryl)sulfonyl)metyl)fenyl)amino) acetate
CAS 592542-61-5C22H27NO8S
Alanine, N-[2-methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]- chemical structure, C22H27NO8S, CAS 592542-82-0
Alanine, N-[2-methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]-
CAS 592542-82-0C22H27NO8S