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Murcko scaffold

5-Phenyl-3-pyridin-3-yl-1,2,4-oxadiazole scaffold

113 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
113
With full pages
29
Scaffold SMILES

c1ccc(-c2nc(-c3cccnc3)no2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Phenyl-3-pyridin-3-yl-1,2,4-oxadiazole page
Murcko scaffold c1ccc(-c2nc(-c3cccnc3)no2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 113 of 113 chemicals

(5-(5-(3-Chloro-4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)pyridin-2-yl)methanol chemical structure, C18H18ClN3O2, CAS 913829-36-4
(5-(5-(3-Chloro-4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)pyridin-2-yl)methanol
CAS 913829-36-4C18H18ClN3O2
Benzoic acid, 3-[3-[6-(dimethylamino)-3-pyridinyl]-1,2,4-oxadiazol-5-yl]-, methyl ester chemical structure, C17H16N4O3, CAS 745055-59-8
Benzoic acid, 3-[3-[6-(dimethylamino)-3-pyridinyl]-1,2,4-oxadiazol-5-yl]-, methyl ester
CAS 745055-59-8C17H16N4O3
3-[3-[6-(Methylamino)-3-pyridinyl]-1,2,4-oxadiazol-5-yl]benzoic acid chemical structure, C15H12N4O3, CAS 745055-26-9
3-[3-[6-(Methylamino)-3-pyridinyl]-1,2,4-oxadiazol-5-yl]benzoic acid
CAS 745055-26-9C15H12N4O3
3-[3-(6-Chloro-3-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile chemical structure, C14H7ClN4O, CAS 1033724-62-7
3-[3-(6-Chloro-3-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile
CAS 1033724-62-7C14H7ClN4O
Opicapone chemical structure, C15H10Cl2N4O6, CAS 923287-50-7
Opicapone
CAS 923287-50-7C15H10Cl2N4O6
5-(3-(2,5-Dichloro-4,6-dimethylpyridin-3-yl)-1,2,4-oxadiazol-5-yl)-3-nitrobenzene-1,2-diol chemical structure, C15H10Cl2N4O5, CAS 952091-17-7
5-(3-(2,5-Dichloro-4,6-dimethylpyridin-3-yl)-1,2,4-oxadiazol-5-yl)-3-nitrobenzene-1,2-diol
CAS 952091-17-7C15H10Cl2N4O5
2-Hydroxy-6-nitro-4-[3-(1-oxo-1lambda~5~-pyridin-3-yl)-1,2,4-oxadiazol-5(2H)-ylidene]cyclohexa-2,5-dien-1-one chemical structure, C13H8N4O6, CAS 923288-11-3
2-Hydroxy-6-nitro-4-[3-(1-oxo-1lambda~5~-pyridin-3-yl)-1,2,4-oxadiazol-5(2H)-ylidene]cyclohexa-2,5-dien-1-one
CAS 923288-11-3C13H8N4O6
4-(3-(2,5-Dichlor-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl)-2-methoxy-6-nitrophenol chemical structure, C16H12Cl2N4O6, CAS 1402714-41-3
4-(3-(2,5-Dichlor-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl)-2-methoxy-6-nitrophenol
CAS 1402714-41-3C16H12Cl2N4O6
4-[3-(2,5-Dichloro-4,6-dimethyl-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-2-methoxy-6-nitrophenol chemical structure, C16H12Cl2N4O5, CAS 1391712-50-7
4-[3-(2,5-Dichloro-4,6-dimethyl-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-2-methoxy-6-nitrophenol
CAS 1391712-50-7C16H12Cl2N4O5
2-Fluoro-4-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)phenol chemical structure, C13H8FN3O2, CAS 1033724-15-0
2-Fluoro-4-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)phenol
CAS 1033724-15-0C13H8FN3O2
3-(2,5-Dichloro-4,6-dimethylpyridin-3-yl)-5-(3,4-dimethoxy-5-nitrophenyl)-1,2,4-oxadiazole chemical structure, C17H14Cl2N4O5, CAS 2356241-50-2
3-(2,5-Dichloro-4,6-dimethylpyridin-3-yl)-5-(3,4-dimethoxy-5-nitrophenyl)-1,2,4-oxadiazole
CAS 2356241-50-2C17H14Cl2N4O5
5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole chemical structure, C14H9F2N3O, CAS 2254004-96-9
5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole
CAS 2254004-96-9C14H9F2N3O
3-(2,5-Dichloro-4,6-dimethyl-1-oxidopyridin-1-ium-3-yl)-5-(3,4-dimethoxy-5-nitrophenyl)-1,2,4-oxadiazole chemical structure, C17H14Cl2N4O6, CAS 2356241-51-3
3-(2,5-Dichloro-4,6-dimethyl-1-oxidopyridin-1-ium-3-yl)-5-(3,4-dimethoxy-5-nitrophenyl)-1,2,4-oxadiazole
CAS 2356241-51-3C17H14Cl2N4O6
Opicapone sulfate metabolite chemical structure, C15H10Cl2N4O9S, CAS 1428009-72-6
Opicapone sulfate metabolite
CAS 1428009-72-6C15H10Cl2N4O9S
4-(3-(2,5-Dichloro-4,6-dimethylpyridin-3-yl)-1,2,4-oxadiazol-5-yl)-2-methoxyphenol chemical structure, C16H13Cl2N3O3, CAS 2824922-36-1
4-(3-(2,5-Dichloro-4,6-dimethylpyridin-3-yl)-1,2,4-oxadiazol-5-yl)-2-methoxyphenol
CAS 2824922-36-1C16H13Cl2N3O3
Entacapone impurity 45 chemical structure, C15H11Cl2N3O4, CAS 2824922-39-4
Entacapone impurity 45
CAS 2824922-39-4C15H11Cl2N3O4
2-Chloro-5-[3-(2,5-dichloro-4,6-dimethyl-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-3-nitrophenol chemical structure, C15H9Cl3N4O4, CAS 1402714-38-8
2-Chloro-5-[3-(2,5-dichloro-4,6-dimethyl-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-3-nitrophenol
CAS 1402714-38-8C15H9Cl3N4O4