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Murcko scaffold

2,5-Diphenyloxazole scaffold

129 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
129
With full pages
16
Scaffold SMILES

c1ccc(-c2cnc(-c3ccccc3)o2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,5-Diphenyloxazole page
Murcko scaffold c1ccc(-c2cnc(-c3ccccc3)o2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 129 chemicals

2,5-Diphenyloxazole chemical structure, C15H11NO, CAS 92-71-7
2,5-Diphenyloxazole
CAS 92-71-7C15H11NO
2-(3-Fluorophenyl)-5-phenyloxazole chemical structure, C15H10FNO, CAS 324-57-2
2-(3-Fluorophenyl)-5-phenyloxazole
CAS 324-57-2C15H10FNO
2-(4-Fluorophenyl)-5-phenyloxazole chemical structure, C15H10FNO, CAS 324-80-1
2-(4-Fluorophenyl)-5-phenyloxazole
CAS 324-80-1C15H10FNO
2-(2-Fluorophenyl)-5-phenyloxazole chemical structure, C15H10FNO, CAS 391-07-1
2-(2-Fluorophenyl)-5-phenyloxazole
CAS 391-07-1C15H10FNO
Oxazole, 4-chloro-2,5-diphenyl- chemical structure, C15H10ClNO, CAS 29431-45-6
Oxazole, 4-chloro-2,5-diphenyl-
CAS 29431-45-6C15H10ClNO
2-(2-Chlorophenyl)-5-phenyl-1,3-oxazole chemical structure, C15H10ClNO, CAS 22397-40-6
2-(2-Chlorophenyl)-5-phenyl-1,3-oxazole
CAS 22397-40-6C15H10ClNO
2-(3-Chlorophenyl)-5-phenyl-1,3-oxazole chemical structure, C15H10ClNO, CAS 57000-63-2
2-(3-Chlorophenyl)-5-phenyl-1,3-oxazole
CAS 57000-63-2C15H10ClNO
2-(4-Chlorophenyl)-5-phenyl-1,3-oxazole chemical structure, C15H10ClNO, CAS 24285-73-2
2-(4-Chlorophenyl)-5-phenyl-1,3-oxazole
CAS 24285-73-2C15H10ClNO
2-(3-Methylphenyl)-5-phenyl-1,3-oxazole chemical structure, C16H13NO, CAS 57532-86-2
2-(3-Methylphenyl)-5-phenyl-1,3-oxazole
CAS 57532-86-2C16H13NO
Oxazole, 2-(4-methylphenyl)-5-phenyl- chemical structure, C16H13NO, CAS 16155-60-5
Oxazole, 2-(4-methylphenyl)-5-phenyl-
CAS 16155-60-5C16H13NO
2-(2-Methylphenyl)-5-phenyl-1,3-oxazole chemical structure, C16H13NO, CAS 17064-20-9
2-(2-Methylphenyl)-5-phenyl-1,3-oxazole
CAS 17064-20-9C16H13NO
2-(2-Bromophenyl)-5-phenyl-1,3-oxazole chemical structure, C15H10BrNO, CAS 37611-27-1
2-(2-Bromophenyl)-5-phenyl-1,3-oxazole
CAS 37611-27-1C15H10BrNO
4-Methyl-2,5-diphenyl-1,3-oxazole chemical structure, C16H13NO, CAS 2549-31-7
4-Methyl-2,5-diphenyl-1,3-oxazole
CAS 2549-31-7C16H13NO
2-(3-Chlorophenyl)-4-methyl-5-phenyl-1,3-oxazole chemical structure, C16H12ClNO, CAS 77876-76-7
2-(3-Chlorophenyl)-4-methyl-5-phenyl-1,3-oxazole
CAS 77876-76-7C16H12ClNO
1-(2,5-Diphenyl-1,3-oxazol-4-yl)ethan-1-one chemical structure, C17H13NO2, CAS 18735-73-4
1-(2,5-Diphenyl-1,3-oxazol-4-yl)ethan-1-one
CAS 18735-73-4C17H13NO2
5-(4-Bromo-phenyl)-2-(4-nitro-phenyl)-oxazole chemical structure, C15H9BrN2O3, CAS 118426-04-3
5-(4-Bromo-phenyl)-2-(4-nitro-phenyl)-oxazole
CAS 118426-04-3C15H9BrN2O3
Balsoxine chemical structure, C17H15NO3, CAS 70216-32-9
Balsoxine
CAS 70216-32-9C17H15NO3
2-(3-Methoxyphenyl)-5-phenyloxazole chemical structure, C16H13NO2, CAS 38705-20-3
2-(3-Methoxyphenyl)-5-phenyloxazole
CAS 38705-20-3C16H13NO2
2-(5-Phenyl-2-oxazolyl)benzoic acid chemical structure, C16H11NO3, CAS 23464-97-3
2-(5-Phenyl-2-oxazolyl)benzoic acid
CAS 23464-97-3C16H11NO3
5-(4-Chlorophenyl)-2-phenyl-1,3-oxazole chemical structure, C15H10ClNO, CAS 80224-89-1
5-(4-Chlorophenyl)-2-phenyl-1,3-oxazole
CAS 80224-89-1C15H10ClNO
5-(4-Bromophenyl)-2-phenyloxazole chemical structure, C15H10BrNO, CAS 96908-21-3
5-(4-Bromophenyl)-2-phenyloxazole
CAS 96908-21-3C15H10BrNO
Methyl 4-{5-[4-(dimethylamino)phenyl]-1,3-oxazol-2-yl}benzoate chemical structure, C19H18N2O3, CAS 108783-69-3
Methyl 4-{5-[4-(dimethylamino)phenyl]-1,3-oxazol-2-yl}benzoate
CAS 108783-69-3C19H18N2O3
2-(4-Methoxyphenyl)-5-phenyl-1,3-oxazole chemical structure, C16H13NO2, CAS 17064-22-1
2-(4-Methoxyphenyl)-5-phenyl-1,3-oxazole
CAS 17064-22-1C16H13NO2
4-(5-Phenyl-1,3-oxazol-2-yl)aniline chemical structure, C15H12N2O, CAS 10004-70-3
4-(5-Phenyl-1,3-oxazol-2-yl)aniline
CAS 10004-70-3C15H12N2O