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Murcko scaffold

Ring system with 2 rings and 13 atoms

66 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
66
With full pages
15
Scaffold SMILES

O=c1[nH]cnnc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cnnc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 66 chemicals

Metamitron chemical structure, C10H10N4O, CAS 41394-05-2
Metamitron
CAS 41394-05-2C10H10N4O
4-Methyl-3-(methylsulfanyl)-6-phenyl-1,2,4-triazin-5(4H)-one chemical structure, C11H11N3OS, CAS 22943-30-2
4-Methyl-3-(methylsulfanyl)-6-phenyl-1,2,4-triazin-5(4H)-one
CAS 22943-30-2C11H11N3OS
2-Ethyl-6-phenyl-1,2,4-triazin-5(2H)-one chemical structure, C11H11N3O, CAS 308276-78-0
2-Ethyl-6-phenyl-1,2,4-triazin-5(2H)-one
CAS 308276-78-0C11H11N3O
1,2,4-Triazin-5(2H)-one, 6-(2-aminophenyl)-2-methyl-3-(methylthio)- chemical structure, C11H12N4OS, CAS 61602-90-2
1,2,4-Triazin-5(2H)-one, 6-(2-aminophenyl)-2-methyl-3-(methylthio)-
CAS 61602-90-2C11H12N4OS
1,2,4-Triazin-5(4H)-one, 6-(2-aminophenyl)-4-methyl-3-(methylthio)- chemical structure, C11H12N4OS, CAS 61602-94-6
1,2,4-Triazin-5(4H)-one, 6-(2-aminophenyl)-4-methyl-3-(methylthio)-
CAS 61602-94-6C11H12N4OS
Bay-79758 chemical structure, C10H10N4OS, CAS 21087-63-8
Bay-79758
CAS 21087-63-8C10H10N4OS
4-Amino-6-phenyl-1,2,4-triazin-5(4H)-one chemical structure, C9H8N4O, CAS 62191-14-4
4-Amino-6-phenyl-1,2,4-triazin-5(4H)-one
CAS 62191-14-4C9H8N4O
4-Amino-3-(hydroxymethyl)-6-phenyl-1,2,4-triazin-5(4H)-one chemical structure, C10H10N4O2, CAS 62191-15-5
4-Amino-3-(hydroxymethyl)-6-phenyl-1,2,4-triazin-5(4H)-one
CAS 62191-15-5C10H10N4O2
4-Amino-3-ethyl-6-phenyl-1,2,4-triazin-5(4H)-one chemical structure, C11H12N4O, CAS 41393-89-9
4-Amino-3-ethyl-6-phenyl-1,2,4-triazin-5(4H)-one
CAS 41393-89-9C11H12N4O
4-Amino-3-(chloromethyl)-6-phenyl-1,2,4-triazin-5(4H)-one chemical structure, C10H9ClN4O, CAS 62191-17-7
4-Amino-3-(chloromethyl)-6-phenyl-1,2,4-triazin-5(4H)-one
CAS 62191-17-7C10H9ClN4O
4-Amino-6-phenyl-3-(trichloromethyl)-1,2,4-triazin-5(4H)-one chemical structure, C10H7Cl3N4O, CAS 62191-18-8
4-Amino-6-phenyl-3-(trichloromethyl)-1,2,4-triazin-5(4H)-one
CAS 62191-18-8C10H7Cl3N4O
4-Amino-3-(dibromomethyl)-6-phenyl-1,2,4-triazin-5(4H)-one chemical structure, C10H8Br2N4O, CAS 62191-20-2
4-Amino-3-(dibromomethyl)-6-phenyl-1,2,4-triazin-5(4H)-one
CAS 62191-20-2C10H8Br2N4O
4-Amino-3-(azidomethyl)-6-phenyl-1,2,4-triazin-5(4H)-one chemical structure, C10H9N7O, CAS 62191-23-5
4-Amino-3-(azidomethyl)-6-phenyl-1,2,4-triazin-5(4H)-one
CAS 62191-23-5C10H9N7O
4-Amino-3-(aminomethyl)-6-phenyl-1,2,4-triazin-5(4H)-one chemical structure, C10H11N5O, CAS 62191-24-6
4-Amino-3-(aminomethyl)-6-phenyl-1,2,4-triazin-5(4H)-one
CAS 62191-24-6C10H11N5O
3-Methyl-4-(methylamino)-6-phenyl-1,2,4-triazin-5(4H)-one chemical structure, C11H12N4O, CAS 56476-19-8
3-Methyl-4-(methylamino)-6-phenyl-1,2,4-triazin-5(4H)-one
CAS 56476-19-8C11H12N4O
3-Ethyl-4-(methylamino)-6-phenyl-1,2,4-triazin-5(4H)-one chemical structure, C12H14N4O, CAS 56476-22-3
3-Ethyl-4-(methylamino)-6-phenyl-1,2,4-triazin-5(4H)-one
CAS 56476-22-3C12H14N4O
3-Ethyl-4-methoxy-6-phenyl-1,2,4-triazin-5(4H)-one chemical structure, C12H13N3O2, CAS 62191-31-5
3-Ethyl-4-methoxy-6-phenyl-1,2,4-triazin-5(4H)-one
CAS 62191-31-5C12H13N3O2
2-Amino-3-(methylsulfanyl)-6-phenyl-1,2,4-triazin-5(2H)-one chemical structure, C10H10N4OS, CAS 81941-53-9
2-Amino-3-(methylsulfanyl)-6-phenyl-1,2,4-triazin-5(2H)-one
CAS 81941-53-9C10H10N4OS
4-Amino-6-phenyl-3-propyl-1,2,4-triazin-5(4H)-one chemical structure, C12H14N4O, CAS 41394-07-4
4-Amino-6-phenyl-3-propyl-1,2,4-triazin-5(4H)-one
CAS 41394-07-4C12H14N4O
2,3-Diamino-6-phenyl-1,2,4-triazin-5(2H)-one chemical structure, C9H9N5O, CAS 89569-68-6
2,3-Diamino-6-phenyl-1,2,4-triazin-5(2H)-one
CAS 89569-68-6C9H9N5O
2-Amino-3-(methylamino)-6-phenyl-1,2,4-triazin-5(2H)-one chemical structure, C10H11N5O, CAS 89569-69-7
2-Amino-3-(methylamino)-6-phenyl-1,2,4-triazin-5(2H)-one
CAS 89569-69-7C10H11N5O
3-(Methylsulfanyl)-4-nitroso-6-phenyl-1,2,4-triazin-5(4H)-one chemical structure, C10H8N4O2S, CAS 106119-80-6
3-(Methylsulfanyl)-4-nitroso-6-phenyl-1,2,4-triazin-5(4H)-one
CAS 106119-80-6C10H8N4O2S
4-Amino-3-ethyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazin-5(4H)-one chemical structure, C12H11F3N4O, CAS 51999-91-8
4-Amino-3-ethyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazin-5(4H)-one
CAS 51999-91-8C12H11F3N4O
N-[3-(Methylsulfanyl)-5-oxo-6-phenyl-1,2,4-triazin-4(5H)-yl]acetamide chemical structure, C12H12N4O2S, CAS 22279-48-7
N-[3-(Methylsulfanyl)-5-oxo-6-phenyl-1,2,4-triazin-4(5H)-yl]acetamide
CAS 22279-48-7C12H12N4O2S