Murcko scaffold
Cyclobutyl phenyl ketone scaffold
188 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 12
- Chemicals
- 188
- With full pages
- 5
Scaffold SMILES
O=C(c1ccccc1)C1CCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 188 chemicals
Cyclobutyl phenyl ketone
CAS 5407-98-7C11H12O
Cyclobutyl 4-fluorophenyl ketone
CAS 31431-13-7C11H11FO
(1-Bromocyclobutyl)(phenyl)methanone
CAS 51175-78-1C11H11BrO
Cyclobutyl(4-hydroxyphenyl)methanone
CAS 184031-01-4C11H12O2
Cyclobutyl 4-methylphenyl ketone
CAS 53342-39-5C12H14O
4-Chlorophenyl cyclobutyl ketone
CAS 77585-25-2C11H11ClO
1-Benzoylcyclobutan-1-ol
CAS 95800-10-5C11H12O2
Cyclobutyl(4-methoxyphenyl)methanone
CAS 100121-80-0C12H14O2
(2-Aminophenyl)(cyclobutyl)methanone
CAS 146374-41-6C11H13NO
Cyclobutyl 2-methylphenyl ketone
CAS 898790-38-0C12H14O
Cyclobutyl 3-methylphenyl ketone
CAS 898790-40-4C12H14O
Cyclobutyl 2-methoxyphenyl ketone
CAS 898790-42-6C12H14O2
Cyclobutyl 3-methoxyphenyl ketone
CAS 898790-44-8C12H14O2
2-Cyanophenyl cyclobutyl ketone
CAS 898790-46-0C12H11NO
3-Cyanophenyl cyclobutyl ketone
CAS 898790-48-2C12H11NO
4-Cyanophenyl cyclobutyl ketone
CAS 898790-50-6C12H11NO
Ethyl 2-(cyclobutanecarbonyl)benzoate
CAS 898790-52-8C14H16O3
Ethyl 3-(cyclobutanecarbonyl)benzoate
CAS 898790-54-0C14H16O3
Ethyl 4-(cyclobutanecarbonyl)benzoate
CAS 801303-28-6C14H16O3
Cyclobutyl 2-thiomethylphenyl ketone
CAS 898790-56-2C12H14OS
Cyclobutyl 4-thiomethylphenyl ketone
CAS 716341-27-4C12H14OS
3-Bromophenyl cyclobutyl ketone
CAS 898790-58-4C11H11BrO
(4-Bromophenyl)(cyclobutyl)methanone
CAS 898790-60-8C11H11BrO
3-Chlorophenyl cyclobutyl ketone
CAS 898790-62-0C11H11ClO
- Cyclobutyl 3-fluorophenyl ketone898790-64-2C11H11FO
- Cyclobutyl 2,3-dimethylphenyl ketone898790-66-4C13H16O
- Cyclobutyl 2,4-dimethylphenyl ketone898790-68-6C13H16O
- Cyclobutyl 2,5-dimethylphenyl ketone898790-70-0C13H16O
- Cyclobutyl 2,6-dimethylphenyl ketone898790-73-3C13H16O
- Cyclobutyl 3,4-dimethylphenyl ketone898790-76-6C13H16O
- Cyclobutyl 3,5-dimethylphenyl ketone898790-79-9C13H16O
- 4-Bromo-3-fluorophenyl cyclobutyl ketone898790-82-4C11H10BrFO
- 4-Chloro-3-fluorophenyl cyclobutyl ketone898790-85-7C11H10ClFO
- 3-Chloro-4-fluorophenyl cyclobutyl ketone898790-88-0C11H10ClFO
- 2-Chlorophenyl cyclobutyl ketone898790-91-5C11H11ClO
- 1 suppliers2-Fluorophenyl cyclobutyl ketone898790-94-8C11H11FO
- Cyclobutyl 2-trifluoromethylphenyl ketone53342-41-9C12H11F3O
- Cyclobutyl 3-trifluoromethylphenyl ketone898790-97-1C12H11F3O
- Cyclobutyl 4-trifluoromethylphenyl ketone53342-40-8C12H11F3O
- 4-Bromo-2-fluorophenyl cyclobutyl ketone898791-00-9C11H10BrFO
- 2-Chloro-4-fluorophenyl cyclobutyl ketone898791-03-2C11H10ClFO
- 3-Chloro-5-fluorophenyl cyclobutyl ketone898791-06-5C11H10ClFO
- 4-Chloro-2-fluorophenyl cyclobutyl ketone898791-09-8C11H10ClFO
- Cyclobutyl 2,3-dichlorophenyl ketone898791-12-3C11H10Cl2O
- Cyclobutyl 2,4-dichlorophenyl ketone898791-15-6C11H10Cl2O
- Cyclobutyl 2,5-dichlorophenyl ketone898791-18-9C11H10Cl2O
- Cyclobutyl 3,4-dichlorophenyl ketone898791-21-4C11H10Cl2O
- Cyclobutyl 3,5-dichlorophenyl ketone898791-24-7C11H10Cl2O
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(CC2CCC2)cc148 chemicals
c1ccc(CC2CNC2)cc141 chemicals
c1ccc(OC2CNC2)cc131 chemicals
c1ccc(CN2CCC2)cc115 chemicals
c1ccc(NC2COC2)cc114 chemicals
c1ccc(NC2CCC2)cc112 chemicals
c1ccc(OC2CCC2)cc112 chemicals
c1ccc(OC2COC2)cc110 chemicals
c1ccc(CC2COC2)cc18 chemicals
O=S(=O)(c1ccccc1)N1CCC18 chemicals
c1ccc(OC2CCC2)nc18 chemicals
C(=C1CNC1)c1ccccc16 chemicals