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Murcko scaffold

3H-Pyrazol-3-one, 2,4-dihydro-2,5-diphenyl- scaffold

39 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
39
With full pages
4
Scaffold SMILES

O=C1CC(c2ccccc2)=NN1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3H-Pyrazol-3-one, 2,4-dihydro-2,5-diphenyl- page
Murcko scaffold O=C1CC(c2ccccc2)=NN1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

3H-Pyrazol-3-one, 2,4-dihydro-2,5-diphenyl- chemical structure, C15H12N2O, CAS 4845-49-2
3H-Pyrazol-3-one, 2,4-dihydro-2,5-diphenyl-
CAS 4845-49-2C15H12N2O
2-(4,5-Dihydro-5-oxo-3-phenyl-1H-pyrazol-1-yl)benzenesulphonic acid chemical structure, C15H12N2O4S, CAS 5855-68-5
2-(4,5-Dihydro-5-oxo-3-phenyl-1H-pyrazol-1-yl)benzenesulphonic acid
CAS 5855-68-5C15H12N2O4S
5-Oxo-1,3-diphenyl-4,5-dihydro-1H-pyrazole-4-carbaldehyde chemical structure, C16H12N2O2, CAS 17364-40-8
5-Oxo-1,3-diphenyl-4,5-dihydro-1H-pyrazole-4-carbaldehyde
CAS 17364-40-8C16H12N2O2
2,5-Diphenyl-4-(3-sulfanylpropyl)-2,4-dihydro-3H-pyrazol-3-one chemical structure, C18H18N2OS, CAS 7767-87-5
2,5-Diphenyl-4-(3-sulfanylpropyl)-2,4-dihydro-3H-pyrazol-3-one
CAS 7767-87-5C18H18N2OS
2,4-Dihydro-4-(2-hydroxyethyl)-2,5-diphenyl-3H-pyrazol-3-one chemical structure, C17H16N2O2, CAS 10223-34-4
2,4-Dihydro-4-(2-hydroxyethyl)-2,5-diphenyl-3H-pyrazol-3-one
CAS 10223-34-4C17H16N2O2
RefChem:381825 chemical structure, C15H11N3O3, CAS 34320-83-7
RefChem:381825
CAS 34320-83-7C15H11N3O3
5-(4-Aminophenyl)-2-phenyl-4H-pyrazol-3-one chemical structure, C15H13N3O, CAS 478398-27-5
5-(4-Aminophenyl)-2-phenyl-4H-pyrazol-3-one
CAS 478398-27-5C15H13N3O
2-(4-Nitrophenyl)-5-phenyl-4H-pyrazol-3-one chemical structure, C15H11N3O3, CAS 60798-14-3
2-(4-Nitrophenyl)-5-phenyl-4H-pyrazol-3-one
CAS 60798-14-3C15H11N3O3
5-Phenyl-2-(2,4,6-trichlorophenyl)-4H-pyrazol-3-one chemical structure, C15H9Cl3N2O, CAS 58376-72-0
5-Phenyl-2-(2,4,6-trichlorophenyl)-4H-pyrazol-3-one
CAS 58376-72-0C15H9Cl3N2O
2-(2,5-Dichlorophenyl)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C15H10Cl2N2O, CAS 118049-89-1
2-(2,5-Dichlorophenyl)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one
CAS 118049-89-1C15H10Cl2N2O
m-(4-(2-Cyanoethyl)-4,5-dihydro-5-oxo-3-(4-((1-oxohexadecyl)amino)phenyl)-1H-pyrazol-1-yl)benzenesulphonic acid chemical structure, C34H46N4O5S, CAS 94944-74-8
m-(4-(2-Cyanoethyl)-4,5-dihydro-5-oxo-3-(4-((1-oxohexadecyl)amino)phenyl)-1H-pyrazol-1-yl)benzenesulphonic acid
CAS 94944-74-8C34H46N4O5S
m-(4-(2-Cyanoethyl)-4,5-dihydro-5-oxo-3-(4-((1-oxooctadecyl)amino)phenyl)-1H-pyrazol-1-yl)benzenesulphonic acid chemical structure, C36H50N4O5S, CAS 94944-75-9
m-(4-(2-Cyanoethyl)-4,5-dihydro-5-oxo-3-(4-((1-oxooctadecyl)amino)phenyl)-1H-pyrazol-1-yl)benzenesulphonic acid
CAS 94944-75-9C36H50N4O5S
m-(4,5-Dihydro-5-oxo-3-(4-((1-oxohexadecyl)amino)phenyl)-1H-pyrazol-1-yl)benzenesulphonic acid chemical structure, C31H43N3O5S, CAS 97158-36-6
m-(4,5-Dihydro-5-oxo-3-(4-((1-oxohexadecyl)amino)phenyl)-1H-pyrazol-1-yl)benzenesulphonic acid
CAS 97158-36-6C31H43N3O5S
3-(4,5-Dihydro-5-oxo-3-(4-((1-oxooctadecyl)amino)phenyl)-1H-pyrazol-1-yl)benzenesulphonic acid chemical structure, C33H47N3O5S, CAS 97158-37-7
3-(4,5-Dihydro-5-oxo-3-(4-((1-oxooctadecyl)amino)phenyl)-1H-pyrazol-1-yl)benzenesulphonic acid
CAS 97158-37-7C33H47N3O5S
2-(3-Chlorophenyl)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C15H11ClN2O, CAS 108124-77-2
2-(3-Chlorophenyl)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one
CAS 108124-77-2C15H11ClN2O
1-(2,4-Dimethylphenyl)-3-phenyl-1H-pyrazole-5(4H)-one chemical structure, C17H16N2O, CAS 1003751-09-4
1-(2,4-Dimethylphenyl)-3-phenyl-1H-pyrazole-5(4H)-one
CAS 1003751-09-4C17H16N2O
5-(4-Methoxyphenyl)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C16H14N2O2, CAS 454439-84-0
5-(4-Methoxyphenyl)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
CAS 454439-84-0C16H14N2O2
4-Bromo-2,5-diphenyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C15H11BrN2O, CAS 56158-61-3
4-Bromo-2,5-diphenyl-2,4-dihydro-3H-pyrazol-3-one
CAS 56158-61-3C15H11BrN2O
2,4-Dihydro-5-(2-methoxyphenyl)-2-phenyl-3H-pyrazol-3-one chemical structure, C16H14N2O2, CAS 60946-74-9
2,4-Dihydro-5-(2-methoxyphenyl)-2-phenyl-3H-pyrazol-3-one
CAS 60946-74-9C16H14N2O2
5-(2,5-Dimethoxyphenyl)-2-phenyl-4H-pyrazol-3-one chemical structure, C17H16N2O3, CAS 60946-76-1
5-(2,5-Dimethoxyphenyl)-2-phenyl-4H-pyrazol-3-one
CAS 60946-76-1C17H16N2O3
2,4-Dihydro-5-(4-fluorophenyl)-2-phenyl-3H-pyrazol-3-one chemical structure, C15H11FN2O, CAS 575455-54-8
2,4-Dihydro-5-(4-fluorophenyl)-2-phenyl-3H-pyrazol-3-one
CAS 575455-54-8C15H11FN2O
1-Phenyl-3-(4-methylphenyl)-4, 5-dihydropyrazol-5-one chemical structure, C16H14N2O, CAS 59848-47-4
1-Phenyl-3-(4-methylphenyl)-4, 5-dihydropyrazol-5-one
CAS 59848-47-4C16H14N2O
1-(4-Chlorophenyl)-3-phenyl-2-pyrazolin-5-one chemical structure, C15H11ClN2O, CAS 60798-13-2
1-(4-Chlorophenyl)-3-phenyl-2-pyrazolin-5-one
CAS 60798-13-2C15H11ClN2O
2-(4-Bromophenyl)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C15H11BrN2O, CAS 87277-69-8
2-(4-Bromophenyl)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one
CAS 87277-69-8C15H11BrN2O