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Murcko scaffold

Ring system with 3 rings and 14 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
17
With full pages
5
Scaffold SMILES

c1nc(-c2ccc3c(c2)CCN3)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nc(-c2ccc3c(c2)CCN3)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

1-[5-(2-Amino-thiazol-4-yl)-2,3-dihydro-indol-1-yl]-2-methyl-butan-1-one chemical structure, C16H19N3OS, CAS 842112-23-6
1-[5-(2-Amino-thiazol-4-yl)-2,3-dihydro-indol-1-yl]-2-methyl-butan-1-one
CAS 842112-23-6C16H19N3OS
1-[5-(2-Amino-5-methyl-4-thiazolyl)-2,3-dihydroindol-1-yl]-1-butanone chemical structure, C16H19N3OS, CAS 842110-52-5
1-[5-(2-Amino-5-methyl-4-thiazolyl)-2,3-dihydroindol-1-yl]-1-butanone
CAS 842110-52-5C16H19N3OS
N-[4-(1-Methylsulfonyl-2,3-dihydroindol-5-yl)-2-thiazolyl]acetamide chemical structure, C14H15N3O3S2, CAS 606121-96-4
N-[4-(1-Methylsulfonyl-2,3-dihydroindol-5-yl)-2-thiazolyl]acetamide
CAS 606121-96-4C14H15N3O3S2
5-Butyl-4-(1-(methylsulfonyl)indolin-5-yl)thiazol-2-amine chemical structure, C16H21N3O2S2, CAS 842112-24-7
5-Butyl-4-(1-(methylsulfonyl)indolin-5-yl)thiazol-2-amine
CAS 842112-24-7C16H21N3O2S2
N-[4-(1-Isobutyryl-2,3-dihydro-1H-indol-5-yl)-5-methyl-1,3-thiazol-2-yl]acetamide chemical structure, C18H21N3O2S, CAS 606121-90-8
N-[4-(1-Isobutyryl-2,3-dihydro-1H-indol-5-yl)-5-methyl-1,3-thiazol-2-yl]acetamide
CAS 606121-90-8C18H21N3O2S
N-{4-[2-Methyl-1-(methylsulfonyl)-2,3-dihydro-1H-indol-5-yl]-1,3-thiazol-2-yl}acetamide chemical structure, C15H17N3O3S2, CAS 606121-97-5
N-{4-[2-Methyl-1-(methylsulfonyl)-2,3-dihydro-1H-indol-5-yl]-1,3-thiazol-2-yl}acetamide
CAS 606121-97-5C15H17N3O3S2
1-(5-(2-Amino-5-methylthiazol-4-yl)indolin-1-yl)ethan-1-one chemical structure, C14H15N3OS, CAS 841221-99-6
1-(5-(2-Amino-5-methylthiazol-4-yl)indolin-1-yl)ethan-1-one
CAS 841221-99-6C14H15N3OS
3-Methyl-N-{4-[2-methyl-1-(methylsulfonyl)-2,3-dihydro-1H-indol-5-yl]-1,3-thiazol-2-yl}butanamide chemical structure, C18H23N3O3S2, CAS 606121-99-7
3-Methyl-N-{4-[2-methyl-1-(methylsulfonyl)-2,3-dihydro-1H-indol-5-yl]-1,3-thiazol-2-yl}butanamide
CAS 606121-99-7C18H23N3O3S2
1-[5-(2-Amino-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one chemical structure, C13H13N3OS, CAS 874787-47-0
1-[5-(2-Amino-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one
CAS 874787-47-0C13H13N3OS
5-(2-Methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indole chemical structure, C12H12N2S, CAS 144340-48-7
5-(2-Methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indole
CAS 144340-48-7C12H12N2S
2-Chloro-1-(5-(2-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl)ethan-1-one chemical structure, C14H13ClN2OS, CAS 940271-56-7
2-Chloro-1-(5-(2-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl)ethan-1-one
CAS 940271-56-7C14H13ClN2OS
4-(1-(Methylsulfonyl)indolin-5-yl)thiazol-2-amine chemical structure, C12H13N3O2S2, CAS 1017135-43-1
4-(1-(Methylsulfonyl)indolin-5-yl)thiazol-2-amine
CAS 1017135-43-1C12H13N3O2S2
5-Methyl-4-(1-(methylsulfonyl)indolin-5-yl)thiazol-2-amine chemical structure, C13H15N3O2S2, CAS 1017162-62-7
5-Methyl-4-(1-(methylsulfonyl)indolin-5-yl)thiazol-2-amine
CAS 1017162-62-7C13H15N3O2S2
2,3-Dihydro-5-(5-methyl-4-thiazolyl)-1H-indole chemical structure, C12H12N2S, CAS 1018603-63-8
2,3-Dihydro-5-(5-methyl-4-thiazolyl)-1H-indole
CAS 1018603-63-8C12H12N2S
4-(1-Methyl-2,3-dihydro-1H-indol-5-yl)-1,3-thiazol-2-amine chemical structure, C12H13N3S, CAS 2228632-13-9
4-(1-Methyl-2,3-dihydro-1H-indol-5-yl)-1,3-thiazol-2-amine
CAS 2228632-13-9C12H13N3S
1-(5-(2-Amino-5-methylthiazol-4-yl)indolin-1-yl)-2-methylpropan-1-one chemical structure, C16H19N3OS, CAS 2804802-22-8
1-(5-(2-Amino-5-methylthiazol-4-yl)indolin-1-yl)-2-methylpropan-1-one
CAS 2804802-22-8C16H19N3OS
1-(5-(2-Amino-5-ethylthiazol-4-yl)indolin-1-yl)ethan-1-one chemical structure, C15H17N3OS, CAS 2804196-88-9
1-(5-(2-Amino-5-ethylthiazol-4-yl)indolin-1-yl)ethan-1-one
CAS 2804196-88-9C15H17N3OS