CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 20 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
5
With full pages
4
Scaffold SMILES

O=c1[nH]c2c(c(=O)[nH]1)C1c3ccccc3OCC1CO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c2c(c(=O)[nH]1)C1c3ccccc3OCC1CO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

2,4-Dimethyl-4,6a,7,12b-tetrahydro-1H,6H-chromeno[4',3':4,5]pyrano[2,3-d]pyrimidine-1,3(2H)-dione chemical structure, C16H16N2O4, CAS 321432-21-7
2,4-Dimethyl-4,6a,7,12b-tetrahydro-1H,6H-chromeno[4',3':4,5]pyrano[2,3-d]pyrimidine-1,3(2H)-dione
CAS 321432-21-7C16H16N2O4
6,6-Dimethyl-4,6a,7,12b-tetrahydro-1H,6H-chromeno[4',3':4,5]pyrano[2,3-d]pyrimidine-1,3(2H)-dione chemical structure, C16H16N2O4, CAS 637322-37-3
6,6-Dimethyl-4,6a,7,12b-tetrahydro-1H,6H-chromeno[4',3':4,5]pyrano[2,3-d]pyrimidine-1,3(2H)-dione
CAS 637322-37-3C16H16N2O4
2,4,6,6-Tetramethyl-4,6a,7,12b-tetrahydro-1H,6H-chromeno[4',3':4,5]pyrano[2,3-d]pyrimidine-1,3(2H)-dione chemical structure, C18H20N2O4, CAS 637322-35-1
2,4,6,6-Tetramethyl-4,6a,7,12b-tetrahydro-1H,6H-chromeno[4',3':4,5]pyrano[2,3-d]pyrimidine-1,3(2H)-dione
CAS 637322-35-1C18H20N2O4
14-Methoxy-4,6-dimethyl-8,12-dioxa-4,6-diazatetracyclo[8.8.0.0^{2,7}.0^{13,18}]octadeca-2(7),13(18),14,16-tetraene-3,5-dione chemical structure, C17H18N2O5, CAS 338794-88-0
14-Methoxy-4,6-dimethyl-8,12-dioxa-4,6-diazatetracyclo[8.8.0.0^{2,7}.0^{13,18}]octadeca-2(7),13(18),14,16-tetraene-3,5-dione
CAS 338794-88-0C17H18N2O5
11-Chloro-2,4-dimethyl-4,6a,7,12b-tetrahydro-1H,6H-chromeno[4',3':4,5]pyrano[2,3-d]pyrimidine-1,3(2H)-dione chemical structure, C16H15ClN2O4, CAS 338954-18-0
11-Chloro-2,4-dimethyl-4,6a,7,12b-tetrahydro-1H,6H-chromeno[4',3':4,5]pyrano[2,3-d]pyrimidine-1,3(2H)-dione
CAS 338954-18-0C16H15ClN2O4