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Murcko scaffold

Ring system with 2 rings and 17 atoms

149 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
149
With full pages
14
Scaffold SMILES

O=C(C=Cc1ccccc1)Oc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)Oc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 149 chemicals

2-Propenoic acid, 3-(4-cyanophenyl)-, 4-butylphenyl ester chemical structure, C20H19NO2, CAS 61924-45-6
2-Propenoic acid, 3-(4-cyanophenyl)-, 4-butylphenyl ester
CAS 61924-45-6C20H19NO2
2-Propenoic acid, 3-(4-cyanophenyl)-, 4-pentylphenyl ester chemical structure, C21H21NO2, CAS 61924-46-7
2-Propenoic acid, 3-(4-cyanophenyl)-, 4-pentylphenyl ester
CAS 61924-46-7C21H21NO2
3,5-Dihydroxyphenyl 3-(4-methoxyphenyl)acrylate chemical structure, C16H14O5, CAS 25528-10-3
3,5-Dihydroxyphenyl 3-(4-methoxyphenyl)acrylate
CAS 25528-10-3C16H14O5
2-Propenoic acid, 3-phenyl-, 4-methoxyphenyl ester chemical structure, C16H14O3, CAS 22867-46-5
2-Propenoic acid, 3-phenyl-, 4-methoxyphenyl ester
CAS 22867-46-5C16H14O3
2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, phenyl ester chemical structure, C15H12O4, CAS 521262-81-7
2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, phenyl ester
CAS 521262-81-7C15H12O4
2-Propenoic acid, 3-phenyl-, 4-methylphenyl ester chemical structure, C16H14O2, CAS 10519-07-0
2-Propenoic acid, 3-phenyl-, 4-methylphenyl ester
CAS 10519-07-0C16H14O2
4-Bromo-2-methylphenyl (2E)-3-phenylprop-2-enoate chemical structure, C16H13BrO2, CAS 433257-01-3
4-Bromo-2-methylphenyl (2E)-3-phenylprop-2-enoate
CAS 433257-01-3C16H13BrO2
RefChem:388636 chemical structure, C20H22O4, CAS 5637-15-0
RefChem:388636
CAS 5637-15-0C20H22O4
Guaiacol cinnamate chemical structure, C16H14O3, CAS 531-40-8
Guaiacol cinnamate
CAS 531-40-8C16H14O3
(E)-4-Ethylphenyl 3-(4-methoxyphenyl)acrylate chemical structure, C18H18O3, CAS 141180-97-4
(E)-4-Ethylphenyl 3-(4-methoxyphenyl)acrylate
CAS 141180-97-4C18H18O3
2-Chlorophenyl (2E)-3-(4-methoxyphenyl)prop-2-enoate chemical structure, C16H13ClO3, CAS 1351447-49-8
2-Chlorophenyl (2E)-3-(4-methoxyphenyl)prop-2-enoate
CAS 1351447-49-8C16H13ClO3
2-Propenoic acid, 3-phenyl-, 4-formylphenyl ester chemical structure, C16H12O3, CAS 85238-61-5
2-Propenoic acid, 3-phenyl-, 4-formylphenyl ester
CAS 85238-61-5C16H12O3
4-(Methylethyl)phenyl (2E)-3-(2,5-dimethoxyphenyl)prop-2-enoate chemical structure, C20H22O4, CAS 304673-60-7
4-(Methylethyl)phenyl (2E)-3-(2,5-dimethoxyphenyl)prop-2-enoate
CAS 304673-60-7C20H22O4
4-Bromophenyl 3-(4-ethoxyphenyl)acrylate chemical structure, C17H15BrO3, CAS 314754-65-9
4-Bromophenyl 3-(4-ethoxyphenyl)acrylate
CAS 314754-65-9C17H15BrO3
2-Propenoic acid, 3-phenyl-, 4-chlorophenyl ester chemical structure, C15H11ClO2, CAS 73789-34-1
2-Propenoic acid, 3-phenyl-, 4-chlorophenyl ester
CAS 73789-34-1C15H11ClO2
2,6-Dimethylphenyl (2E)-3-(2-methoxyphenyl)prop-2-enoate chemical structure, C18H18O3, CAS 691365-52-3
2,6-Dimethylphenyl (2E)-3-(2-methoxyphenyl)prop-2-enoate
CAS 691365-52-3C18H18O3
2-Propenoic acid, 3-(4-methoxyphenyl)-, 4-methoxyphenyl ester, (E)- chemical structure, C17H16O4, CAS 141220-41-9
2-Propenoic acid, 3-(4-methoxyphenyl)-, 4-methoxyphenyl ester, (E)-
CAS 141220-41-9C17H16O4
Phenyl cinnamate chemical structure, C15H12O2, CAS 2757-04-2
Phenyl cinnamate
CAS 2757-04-2C15H12O2
4-Nitrophenyl (2E)-3-phenylprop-2-enoate chemical structure, C15H11NO4, CAS 71721-74-9
4-Nitrophenyl (2E)-3-phenylprop-2-enoate
CAS 71721-74-9C15H11NO4
2-Propenoic acid, 3-phenyl-, 4-acetylphenyl ester chemical structure, C17H14O3, CAS 84796-16-7
2-Propenoic acid, 3-phenyl-, 4-acetylphenyl ester
CAS 84796-16-7C17H14O3
2-Propenoic acid, 3-(4-methoxyphenyl)-, 4-methylphenyl ester chemical structure, C17H16O3, CAS 132367-47-6
2-Propenoic acid, 3-(4-methoxyphenyl)-, 4-methylphenyl ester
CAS 132367-47-6C17H16O3
4-Methylphenyl (2E)-3-(4-methoxyphenyl)prop-2-enoate chemical structure, C17H16O3, CAS 100924-91-2
4-Methylphenyl (2E)-3-(4-methoxyphenyl)prop-2-enoate
CAS 100924-91-2C17H16O3
2-Propenoic acid, 3-(4-methoxyphenyl)-, 4-chlorophenyl ester, (E)- chemical structure, C16H13ClO3, CAS 123282-71-3
2-Propenoic acid, 3-(4-methoxyphenyl)-, 4-chlorophenyl ester, (E)-
CAS 123282-71-3C16H13ClO3
3-Methylphenyl (2E)-3-(4-methoxyphenyl)prop-2-enoate chemical structure, C17H16O3, CAS 431926-35-1
3-Methylphenyl (2E)-3-(4-methoxyphenyl)prop-2-enoate
CAS 431926-35-1C17H16O3