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Murcko scaffold

5H-Pyrrolo[2,3-d]pyrimidin-6(7H)-one scaffold

49 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 10
Chemicals: 49
With full pages: 9

Scaffold SMILES

O=C1Cc2cncnc2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 5H-Pyrrolo[2,3-d]pyrimidin-6(7H)-one page

Murcko scaffold O=C1Cc2cncnc2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 49 chemicals

2-Chloro-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one chemical structure, C6H4ClN3O, CAS 335654-08-5

2-Chloro-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one

CAS 335654-08-5C₆H₄ClN₃O

6H-Pyrrolo(2,3-d)pyrimidin-6-one, 5,7-dihydro-7-methyl-2-((1-methylethyl)amino)-, monohydrochloride chemical structure, C10H15ClN4O, CAS 122113-10-4

6H-Pyrrolo(2,3-d)pyrimidin-6-one, 5,7-dihydro-7-methyl-2-((1-methylethyl)amino)-, monohydrochloride

CAS 122113-10-4C₁₀H₁₅ClN₄O

6H-Pyrrolo(2,3-d)pyrimidin-6-one, 5,7-dihydro-2-(dimethylamino)-7-methyl-, (Z)-2-butenedioate (1:1) chemical structure, C13H16N4O5, CAS 122113-42-2

6H-Pyrrolo(2,3-d)pyrimidin-6-one, 5,7-dihydro-2-(dimethylamino)-7-methyl-, (Z)-2-butenedioate (1:1)

CAS 122113-42-2C₁₃H₁₆N₄O₅

2-Ethenyl-5,7-dihydropyrrolo[2,3-d]pyrimidin-6-one chemical structure, C8H7N3O, CAS 335654-09-6

2-Ethenyl-5,7-dihydropyrrolo[2,3-d]pyrimidin-6-one

CAS 335654-09-6C₈H₇N₃O

4-Chloro-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one chemical structure, C6H4ClN3O, CAS 346599-63-1

4-Chloro-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one

CAS 346599-63-1C₆H₄ClN₃O

5H-Pyrrolo[2,3-d]pyrimidin-6(7H)-one chemical structure, C6H5N3O, CAS 5817-96-9

5H-Pyrrolo[2,3-d]pyrimidin-6(7H)-one

CAS 5817-96-9C₆H₅N₃O

2-Methyl-1H-pyrrolo[2,3-d]pyrimidin-6(5H)-one chemical structure, C7H7N3O, CAS 118801-71-1

2-Methyl-1H-pyrrolo[2,3-d]pyrimidin-6(5H)-one

CAS 118801-71-1C₇H₇N₃O

7-Methyl-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one chemical structure, C7H7N3O, CAS 1638759-51-9

7-Methyl-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one

CAS 1638759-51-9C₇H₇N₃O

2-Amino-5,5-diethyl-7-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one chemical structure, C11H16N4O, CAS 1184916-15-1

2-Amino-5,5-diethyl-7-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one

CAS 1184916-15-1C₁₁H₁₆N₄O

2-Amino-5,5,7-trimethyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one chemical structure, C9H12N4O, CAS 1184915-92-1

2-Amino-5,5,7-trimethyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one

CAS 1184915-92-1C₉H₁₂N₄O

2-Amino-7-(2-hydroxyethyl)-5,5-dimethyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one chemical structure, C10H14N4O2, CAS 1184917-09-6

2-Amino-7-(2-hydroxyethyl)-5,5-dimethyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one

CAS 1184917-09-6C₁₀H₁₄N₄O₂

2-(Methylsulfanyl)-5H,6H,7H-pyrrolo(2,3-d)pyrimidin-6-one chemical structure, C7H7N3OS, CAS 1251003-59-4

2-(Methylsulfanyl)-5H,6H,7H-pyrrolo(2,3-d)pyrimidin-6-one

CAS 1251003-59-4C₇H₇N₃OS

Methyl 6,7-dihydro-6-oxo-5H-pyrrolo[2,3-D]pyrimidine-4-carboxylate chemical structure, C8H7N3O3, CAS 1095822-24-4

Methyl 6,7-dihydro-6-oxo-5H-pyrrolo[2,3-D]pyrimidine-4-carboxylate

CAS 1095822-24-4C₈H₇N₃O₃

6-Oxo-6,7-dihydro-5H-pyrrolo[2,3-D]pyrimidine-4-carboxylic acid chemical structure, C7H5N3O3, CAS 1095824-74-0

6-Oxo-6,7-dihydro-5H-pyrrolo[2,3-D]pyrimidine-4-carboxylic acid

CAS 1095824-74-0C₇H₅N₃O₃

5,5-Dimethyl-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one chemical structure, C8H9N3O, CAS 1638761-01-9

5,5-Dimethyl-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one

CAS 1638761-01-9C₈H₉N₃O

2-Chloro-7-(pentan-3-yl)-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one chemical structure, C11H14ClN3O, CAS 959795-60-9

2-Chloro-7-(pentan-3-yl)-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one

CAS 959795-60-9C₁₁H₁₄ClN₃O

2-Chloro-7-methyl-5H,6H,7H-pyrrolo(2,3-d)pyrimidin-6-one chemical structure, C7H6ClN3O, CAS 1547032-37-0

2-Chloro-7-methyl-5H,6H,7H-pyrrolo(2,3-d)pyrimidin-6-one

CAS 1547032-37-0C₇H₆ClN₃O

4-Chloro-5-ethyl-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one chemical structure, C8H8ClN3O, CAS 1226804-04-1

4-Chloro-5-ethyl-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one

CAS 1226804-04-1C₈H₈ClN₃O

4-Chloro-5-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one chemical structure, C7H6ClN3O, CAS 1226804-06-3

4-Chloro-5-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one

CAS 1226804-06-3C₇H₆ClN₃O

4-Chloro-2-methoxy-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one chemical structure, C7H6ClN3O2, CAS 1093799-53-1

4-Chloro-2-methoxy-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one

CAS 1093799-53-1C₇H₆ClN₃O₂

4-Methyl-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one chemical structure, C7H7N3O, CAS 1780051-28-6

4-Methyl-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one

CAS 1780051-28-6C₇H₇N₃O

2-CHLORO-5H-PYRROLO[2,3-D]PYRIMIDIN-6(7H)-ONE hydrochloride chemical structure, C6H5Cl2N3O, CAS 1404373-76-7

2-CHLORO-5H-PYRROLO[2,3-D]PYRIMIDIN-6(7H)-ONE hydrochloride

CAS 1404373-76-7C₆H₅Cl₂N₃O

4-Chloro-7-methyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one chemical structure, C7H6ClN3O, CAS 1234616-35-3

4-Chloro-7-methyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one

CAS 1234616-35-3C₇H₆ClN₃O

2-Chloro-5,5-dimethyl-7-(pentan-3-yl)-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one chemical structure, C13H18ClN3O, CAS 959799-06-5

2-Chloro-5,5-dimethyl-7-(pentan-3-yl)-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one

CAS 959799-06-5C₁₃H₁₈ClN₃O