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Murcko scaffold

Ring system with 2 rings and 13 atoms

27 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
27
With full pages
3
Scaffold SMILES

C(=Cc1ccccc1)C1=NCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1ccccc1)C1=NCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

Oxazolium, 2-[2-[4-(dimethylamino)phenyl]ethenyl]-4,5-dihydro-4-(hydroxymethyl)-3,4-dimethyl-, iodide (1:1) chemical structure, C16H23IN2O2, CAS 27822-88-4
Oxazolium, 2-[2-[4-(dimethylamino)phenyl]ethenyl]-4,5-dihydro-4-(hydroxymethyl)-3,4-dimethyl-, iodide (1:1)
CAS 27822-88-4C16H23IN2O2
4,4-Dimethyl-2-(2-phenylethenyl)-2-oxazoline chemical structure, C13H15NO, CAS 121578-58-3
4,4-Dimethyl-2-(2-phenylethenyl)-2-oxazoline
CAS 121578-58-3C13H15NO
4,4-Dimethyl-2-[(E)-2-(3-nitrophenyl)ethenyl]-5H-1,3-oxazole chemical structure, C13H14N2O3, CAS 100098-55-3
4,4-Dimethyl-2-[(E)-2-(3-nitrophenyl)ethenyl]-5H-1,3-oxazole
CAS 100098-55-3C13H14N2O3
4,4-Dimethyl-2-[(E)-2-(4-nitrophenyl)ethenyl]-5H-1,3-oxazole chemical structure, C13H14N2O3, CAS 1164487-92-6
4,4-Dimethyl-2-[(E)-2-(4-nitrophenyl)ethenyl]-5H-1,3-oxazole
CAS 1164487-92-6C13H14N2O3
(2-[(E)-2-Phenylvinyl]-4,5-dihydro-1,3-oxazole-4,4-diyl)dimethanol chemical structure, C13H15NO3, CAS 55435-56-8
(2-[(E)-2-Phenylvinyl]-4,5-dihydro-1,3-oxazole-4,4-diyl)dimethanol
CAS 55435-56-8C13H15NO3
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-phenylethenyl)- chemical structure, C13H15NO, CAS 1615-22-1
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-phenylethenyl)-
CAS 1615-22-1C13H15NO
Oxazole, 4,5-dihydro-2-(2-(4-chlorophenyl)ethenyl)-4,4-dimethyl- chemical structure, C13H14ClNO, CAS 1751-77-5
Oxazole, 4,5-dihydro-2-(2-(4-chlorophenyl)ethenyl)-4,4-dimethyl-
CAS 1751-77-5C13H14ClNO
Oxazole, 4,5-dihydro-2-(2-(3-chlorophenyl)ethenyl)-4,4-dimethyl- chemical structure, C13H14ClNO, CAS 53644-87-4
Oxazole, 4,5-dihydro-2-(2-(3-chlorophenyl)ethenyl)-4,4-dimethyl-
CAS 53644-87-4C13H14ClNO
Oxazole, 4,5-dihydro-2-(2-(3,5-dimethoxyphenyl)-1-methylethenyl)-4,4-dimethyl- chemical structure, C16H21NO3, CAS 53644-88-5
Oxazole, 4,5-dihydro-2-(2-(3,5-dimethoxyphenyl)-1-methylethenyl)-4,4-dimethyl-
CAS 53644-88-5C16H21NO3
Oxazole, 4,5-dihydro-2-(2-(2-chlorophenyl)ethenyl)-4,4-dimethyl- chemical structure, C13H14ClNO, CAS 53644-89-6
Oxazole, 4,5-dihydro-2-(2-(2-chlorophenyl)ethenyl)-4,4-dimethyl-
CAS 53644-89-6C13H14ClNO
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-(3,4,5-trimethoxyphenyl)ethenyl)- chemical structure, C16H21NO4, CAS 53644-91-0
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-(3,4,5-trimethoxyphenyl)ethenyl)-
CAS 53644-91-0C16H21NO4
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-(4-methoxyphenyl)-1-methylethenyl)- chemical structure, C15H19NO2, CAS 53644-92-1
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-(4-methoxyphenyl)-1-methylethenyl)-
CAS 53644-92-1C15H19NO2
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-(3-methoxyphenyl)-1-methylethenyl)- chemical structure, C15H19NO2, CAS 53644-95-4
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-(3-methoxyphenyl)-1-methylethenyl)-
CAS 53644-95-4C15H19NO2
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(1-methoxy-2-phenylethenyl)- chemical structure, C14H17NO2, CAS 53644-97-6
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(1-methoxy-2-phenylethenyl)-
CAS 53644-97-6C14H17NO2
Oxazole, 4,5-dihydro-2-(1-((3,5-dimethoxyphenyl)methylene)-9-decenyl)-4,4-dimethyl- chemical structure, C24H35NO3, CAS 53746-84-2
Oxazole, 4,5-dihydro-2-(1-((3,5-dimethoxyphenyl)methylene)-9-decenyl)-4,4-dimethyl-
CAS 53746-84-2C24H35NO3
Oxazole, 4,5-dihydro-2-(2-(4-chloro-3-nitrophenyl)ethenyl)-4,4-dimethyl-, monohydrochloride, (E)- chemical structure, C13H14Cl2N2O3, CAS 100098-73-5
Oxazole, 4,5-dihydro-2-(2-(4-chloro-3-nitrophenyl)ethenyl)-4,4-dimethyl-, monohydrochloride, (E)-
CAS 100098-73-5C13H14Cl2N2O3
Oxazole, 4,5-dihydro-2-(2-(3,4-dichlorophenyl)ethenyl)-4,4-dimethyl-, hydrochloride, (E)- chemical structure, C13H14Cl3NO, CAS 100098-74-6
Oxazole, 4,5-dihydro-2-(2-(3,4-dichlorophenyl)ethenyl)-4,4-dimethyl-, hydrochloride, (E)-
CAS 100098-74-6C13H14Cl3NO
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-(3,5-dinitrophenyl)ethenyl)-, monohydrochloride, (E)- chemical structure, C13H14ClN3O5, CAS 100098-75-7
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-(3,5-dinitrophenyl)ethenyl)-, monohydrochloride, (E)-
CAS 100098-75-7C13H14ClN3O5
Oxazole, 4,5-dihydro-2-(2-(3-bromophenyl)ethenyl)-4,4-dimethyl-, hydrochloride, (E)- chemical structure, C13H15BrClNO, CAS 100098-76-8
Oxazole, 4,5-dihydro-2-(2-(3-bromophenyl)ethenyl)-4,4-dimethyl-, hydrochloride, (E)-
CAS 100098-76-8C13H15BrClNO
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-(3-nitrophenyl)ethenyl)-, monohydrochloride, (E)- chemical structure, C13H15ClN2O3, CAS 100098-77-9
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-(3-nitrophenyl)ethenyl)-, monohydrochloride, (E)-
CAS 100098-77-9C13H15ClN2O3
Oxazole, 4,5-dihydro-2-(2-(3,4-dimethoxyphenyl)ethenyl)-4,4-dimethyl-, hydrochloride, (E)- chemical structure, C15H20ClNO3, CAS 100098-81-5
Oxazole, 4,5-dihydro-2-(2-(3,4-dimethoxyphenyl)ethenyl)-4,4-dimethyl-, hydrochloride, (E)-
CAS 100098-81-5C15H20ClNO3
(4S)-4-tert-Butyl-2-[(E)-2-(2-methoxyphenyl)ethenyl]-4,5-dihydro-1,3-oxazole chemical structure, C16H21NO2, CAS 137542-80-4
(4S)-4-tert-Butyl-2-[(E)-2-(2-methoxyphenyl)ethenyl]-4,5-dihydro-1,3-oxazole
CAS 137542-80-4C16H21NO2
5,5-Dimethyl-2-(2-phenylethenyl)-4,5-dihydro-1,3-oxazole chemical structure, C13H15NO, CAS 124210-99-7
5,5-Dimethyl-2-(2-phenylethenyl)-4,5-dihydro-1,3-oxazole
CAS 124210-99-7C13H15NO
(4S)-2-(2-Phenylethenyl)-4-(propan-2-yl)-4,5-dihydro-1,3-oxazole chemical structure, C14H17NO, CAS 379690-29-6
(4S)-2-(2-Phenylethenyl)-4-(propan-2-yl)-4,5-dihydro-1,3-oxazole
CAS 379690-29-6C14H17NO