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Murcko scaffold

5,6,7,8-Tetrahydro-1,6-naphthyridin-4-ol scaffold

26 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
26
With full pages
5
Scaffold SMILES

O=c1cc[nH]c2c1CNCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6,7,8-Tetrahydro-1,6-naphthyridin-4-ol page
Murcko scaffold O=c1cc[nH]c2c1CNCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

Diethyl 4-Hydroxy-7,8-dihydro-1,6-naphthyridine-3,6(5H)-dicarboxylate chemical structure, C14H18N2O5, CAS 102200-71-5
Diethyl 4-Hydroxy-7,8-dihydro-1,6-naphthyridine-3,6(5H)-dicarboxylate
CAS 102200-71-5C14H18N2O5
6-(Ethoxycarbonyl)-4-oxo-1,4,5,6,7,8-hexahydro-1,6-naphthyridine-3-carboxylic acid chemical structure, C12H14N2O5, CAS 1201845-44-4
6-(Ethoxycarbonyl)-4-oxo-1,4,5,6,7,8-hexahydro-1,6-naphthyridine-3-carboxylic acid
CAS 1201845-44-4C12H14N2O5
Ethyl 4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylate chemical structure, C11H14N2O3, CAS 102200-78-2
Ethyl 4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylate
CAS 102200-78-2C11H14N2O3
Ethyl 4-oxo-4,5,7,8-tetrahydro-1,6-naphthyridine-6(1H)-carboxylate chemical structure, C11H14N2O3, CAS 1201845-46-6
Ethyl 4-oxo-4,5,7,8-tetrahydro-1,6-naphthyridine-6(1H)-carboxylate
CAS 1201845-46-6C11H14N2O3
4-Hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylic acid chemical structure, C9H10N2O3, CAS 1784382-81-5
4-Hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylic acid
CAS 1784382-81-5C9H10N2O3
Methyl 4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylate chemical structure, C10H12N2O3, CAS 1694535-88-0
Methyl 4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylate
CAS 1694535-88-0C10H12N2O3
6-tert-Butyl 3-ethyl 4-hydroxy-7,8-dihydro-1,6-naphthyridine-3,6(5H)-dicarboxylate chemical structure, C16H22N2O5, CAS 1823496-86-1
6-tert-Butyl 3-ethyl 4-hydroxy-7,8-dihydro-1,6-naphthyridine-3,6(5H)-dicarboxylate
CAS 1823496-86-1C16H22N2O5
tert-Butyl 4-hydroxy-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate chemical structure, C13H18N2O3, CAS 1823566-38-6
tert-Butyl 4-hydroxy-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate
CAS 1823566-38-6C13H18N2O3
5,6,7,8-Tetrahydro-1,6-naphthyridin-4-ol chemical structure, C8H10N2O, CAS 2138045-40-4
5,6,7,8-Tetrahydro-1,6-naphthyridin-4-ol
CAS 2138045-40-4C8H10N2O
5,6,7,8-Tetrahydro-1,6-naphthyridin-4-ol dihydrochloride chemical structure, C8H12Cl2N2O, CAS 2138045-41-5
5,6,7,8-Tetrahydro-1,6-naphthyridin-4-ol dihydrochloride
CAS 2138045-41-5C8H12Cl2N2O
tert-Butyl 3-bromo-4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate chemical structure, C13H17BrN2O3, CAS 2138035-81-9
tert-Butyl 3-bromo-4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate
CAS 2138035-81-9C13H17BrN2O3
3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridin-4-ol hydrochloride chemical structure, C8H10BrClN2O, CAS 2138549-03-6
3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridin-4-ol hydrochloride
CAS 2138549-03-6C8H10BrClN2O
3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridin-4-ol chemical structure, C8H9BrN2O, CAS 2138114-45-9
3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridin-4-ol
CAS 2138114-45-9C8H9BrN2O
Methyl 4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylate dihydrochloride chemical structure, C10H14Cl2N2O3, CAS 2193065-21-1
Methyl 4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylate dihydrochloride
CAS 2193065-21-1C10H14Cl2N2O3
4-Hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylic acid hydrochloride chemical structure, C9H11ClN2O3, CAS 2219369-14-7
4-Hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylic acid hydrochloride
CAS 2219369-14-7C9H11ClN2O3
tert-Butyl 4-hydroxy-3-iodo-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate chemical structure, C13H17IN2O3, CAS 2219370-58-6
tert-Butyl 4-hydroxy-3-iodo-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate
CAS 2219370-58-6C13H17IN2O3
3-Iodo-1,4,5,6,7,8-hexahydro-1,6-naphthyridin-4-one hydrochloride chemical structure, C8H10ClIN2O, CAS 2219374-22-6
3-Iodo-1,4,5,6,7,8-hexahydro-1,6-naphthyridin-4-one hydrochloride
CAS 2219374-22-6C8H10ClIN2O
3-Iodo-1,4,5,6,7,8-hexahydro-1,6-naphthyridin-4-one chemical structure, C8H9IN2O, CAS 2219374-21-5
3-Iodo-1,4,5,6,7,8-hexahydro-1,6-naphthyridin-4-one
CAS 2219374-21-5C8H9IN2O
6-[(tert-Butoxy)carbonyl]-4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylic acid chemical structure, C14H18N2O5, CAS 2219376-82-4
6-[(tert-Butoxy)carbonyl]-4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylic acid
CAS 2219376-82-4C14H18N2O5
4-Hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylic acid dihydrochloride chemical structure, C9H12Cl2N2O3, CAS 2225135-92-0
4-Hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylic acid dihydrochloride
CAS 2225135-92-0C9H12Cl2N2O3
5,6,7,8-Tetrahydro[1,6]naphthyridin-4-ol hydrochloride chemical structure, C8H11ClN2O, CAS 2203717-10-4
5,6,7,8-Tetrahydro[1,6]naphthyridin-4-ol hydrochloride
CAS 2203717-10-4C8H11ClN2O
6-tert-Butyl 3-methyl 4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3,6-dicarboxylate chemical structure, C15H20N2O5, CAS 2413884-35-0
6-tert-Butyl 3-methyl 4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3,6-dicarboxylate
CAS 2413884-35-0C15H20N2O5
tert-Butyl 4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylate chemical structure, C13H18N2O3, CAS 2639425-59-3
tert-Butyl 4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylate
CAS 2639425-59-3C13H18N2O3
6-Acetyl-4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylic acid chemical structure, C11H12N2O4, CAS 2680767-57-9
6-Acetyl-4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylic acid
CAS 2680767-57-9C11H12N2O4