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Murcko scaffold

Ring system with 3 rings and 17 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
17
With full pages
4
Scaffold SMILES

c1ccc(-n2ccc(-c3ccncc3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-n2ccc(-c3ccncc3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

1-Phenyl-3-(pyridin-4-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C15H11N3O, CAS 371917-81-6
1-Phenyl-3-(pyridin-4-yl)-1H-pyrazole-4-carbaldehyde
CAS 371917-81-6C15H11N3O
2-Cyano-N-methyl-3-[1-phenyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]prop-2-enamide chemical structure, C19H15N5O, CAS 7061-39-4
2-Cyano-N-methyl-3-[1-phenyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]prop-2-enamide
CAS 7061-39-4C19H15N5O
1-Phenyl-3-(pyridin-4-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C15H11N3O2, CAS 957354-76-6
1-Phenyl-3-(pyridin-4-yl)-1H-pyrazole-4-carboxylic acid
CAS 957354-76-6C15H11N3O2
3-Pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-4-carboxylic acid chemical structure, C16H10F3N3O2, CAS 400076-49-5
3-Pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-4-carboxylic acid
CAS 400076-49-5C16H10F3N3O2
N-Methyl-3-(4-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide chemical structure, C17H13F3N4O, CAS 400076-54-2
N-Methyl-3-(4-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide
CAS 400076-54-2C17H13F3N4O
Methyl 1-phenyl-3-(4-pyridinyl)-1H-pyrazole-4-carboxylate chemical structure, C16H13N3O2, CAS 400074-76-2
Methyl 1-phenyl-3-(4-pyridinyl)-1H-pyrazole-4-carboxylate
CAS 400074-76-2C16H13N3O2
2-Cyano-N-(3-methoxypropyl)-3-[1-phenyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]prop-2-enamide chemical structure, C22H21N5O2, CAS 1020457-70-8
2-Cyano-N-(3-methoxypropyl)-3-[1-phenyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]prop-2-enamide
CAS 1020457-70-8C22H21N5O2
(1-(4-Fluorophenyl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl)methanol chemical structure, C15H12FN3O, CAS 948293-42-3
(1-(4-Fluorophenyl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl)methanol
CAS 948293-42-3C15H12FN3O
1-Phenyl-3-(pyridin-4-yl)-1H-pyrazol-5-amine chemical structure, C14H12N4, CAS 6043-00-1
1-Phenyl-3-(pyridin-4-yl)-1H-pyrazol-5-amine
CAS 6043-00-1C14H12N4
1-Phenyl-3-(pyridin-4-yl)-1H-pyrazole-4-carboxylic acid hydrate chemical structure, C15H13N3O3, CAS 1209311-70-5
1-Phenyl-3-(pyridin-4-yl)-1H-pyrazole-4-carboxylic acid hydrate
CAS 1209311-70-5C15H13N3O3
[1-Phenyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]methanamine chemical structure, C15H14N4, CAS 1221723-97-2
[1-Phenyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]methanamine
CAS 1221723-97-2C15H14N4
5-Azido-1-phenyl-3-(pyridin-4-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C15H10N6O, CAS 848355-74-8
5-Azido-1-phenyl-3-(pyridin-4-yl)-1H-pyrazole-4-carbaldehyde
CAS 848355-74-8C15H10N6O
3-(Pyridin-4-yl)-1-o-tolyl-1H-pyrazole-5-carboxylic acid chemical structure, C16H13N3O2, CAS 1202029-86-4
3-(Pyridin-4-yl)-1-o-tolyl-1H-pyrazole-5-carboxylic acid
CAS 1202029-86-4C16H13N3O2
1-Phenyl-3-(pyridin-4-yl)-1H-pyrazol-4-amine chemical structure, C14H12N4, CAS 1556941-89-9
1-Phenyl-3-(pyridin-4-yl)-1H-pyrazol-4-amine
CAS 1556941-89-9C14H12N4
(3-(Pyridin-4-yl)-1-p-tolyl-1H-pyrazol-4-yl)methanol chemical structure, C16H15N3O, CAS 1020237-70-0
(3-(Pyridin-4-yl)-1-p-tolyl-1H-pyrazol-4-yl)methanol
CAS 1020237-70-0C16H15N3O
1-(4-Fluorophenyl)-3-(4-pyridinyl)-1H-pyrazol-5-amine chemical structure, C14H11FN4, CAS 1810856-42-8
1-(4-Fluorophenyl)-3-(4-pyridinyl)-1H-pyrazol-5-amine
CAS 1810856-42-8C14H11FN4
4-[4-Bromo-3-(4-pyridinyl)-1H-pyrazol-1-yl]phenol chemical structure, C14H10BrN3O, CAS 2230958-18-4
4-[4-Bromo-3-(4-pyridinyl)-1H-pyrazol-1-yl]phenol
CAS 2230958-18-4C14H10BrN3O