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Murcko scaffold

Ring system with 3 rings and 15 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
10
With full pages
5
Scaffold SMILES

O=C1C=CC2CCC3CC(=O)OC3C2=C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CC2CCC3CC(=O)OC3C2=C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

3,5a,9-Trimethyl-3a,5,5a,9b-tetrahydronaphtho[1,2-b]furan-2,8(3H,4H)-dione chemical structure, C15H18O3, CAS 3650-48-4
3,5a,9-Trimethyl-3a,5,5a,9b-tetrahydronaphtho[1,2-b]furan-2,8(3H,4H)-dione
CAS 3650-48-4C15H18O3
Artemisin chemical structure, C15H18O4, CAS 481-05-0
Artemisin
CAS 481-05-0C15H18O4
(-)-Santonin chemical structure, C15H18O3, CAS 481-06-1
(-)-Santonin
CAS 481-06-1C15H18O3
(3R,3aS,5aS,9bS)-3a,5,5a,9b-Tetrahydro-3,5a,9-trimethylnaphtho(1,2-b)furan-2,8(3H,4H)-dione chemical structure, C15H18O3, CAS 481-07-2
(3R,3aS,5aS,9bS)-3a,5,5a,9b-Tetrahydro-3,5a,9-trimethylnaphtho(1,2-b)furan-2,8(3H,4H)-dione
CAS 481-07-2C15H18O3
2-Bromosantonin chemical structure, C15H17BrO3, CAS 5676-49-3
2-Bromosantonin
CAS 5676-49-3C15H17BrO3
alpha-Chlorosantonin chemical structure, C15H17ClO3, CAS 28136-94-9
alpha-Chlorosantonin
CAS 28136-94-9C15H17ClO3
Cedrin chemical structure, C15H18O6, CAS 6040-62-6
Cedrin
CAS 6040-62-6C15H18O6
6,11-Alpha(H)-santonin chemical structure, C15H18O3, CAS 1618-78-6
6,11-Alpha(H)-santonin
CAS 1618-78-6C15H18O3
(3R)-3abeta,5,5a,9bbeta-Tetrahydro-3alpha,5aalpha,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione chemical structure, C15H18O3, CAS 1618-77-5
(3R)-3abeta,5,5a,9bbeta-Tetrahydro-3alpha,5aalpha,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione
CAS 1618-77-5C15H18O3
(+)-Decipienin A chemical structure, C20H24O5, CAS 51848-01-2
(+)-Decipienin A
CAS 51848-01-2C20H24O5