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Murcko scaffold

Ring system with 2 rings and 12 atoms

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
22
With full pages
4
Scaffold SMILES

c1noc(CN2CCNCC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1noc(CN2CCNCC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

1-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]piperazine chemical structure, C8H14N4O, CAS 1042795-94-7
1-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]piperazine
CAS 1042795-94-7C8H14N4O
1-{[3-(Propan-2-yl)-1,2,4-oxadiazol-5-yl]methyl}piperazine chemical structure, C10H18N4O, CAS 1021286-86-1
1-{[3-(Propan-2-yl)-1,2,4-oxadiazol-5-yl]methyl}piperazine
CAS 1021286-86-1C10H18N4O
1-((3-(Propan-2-yl)-1,2,4-oxadiazol-5-yl)methyl)piperazine dihydrochloride chemical structure, C10H20Cl2N4O, CAS 1172924-80-9
1-((3-(Propan-2-yl)-1,2,4-oxadiazol-5-yl)methyl)piperazine dihydrochloride
CAS 1172924-80-9C10H20Cl2N4O
2-(4-((3-Propyl-1,2,4-oxadiazol-5-yl)methyl)piperazin-1-yl)ethan-1-ol chemical structure, C12H22N4O2, CAS 1070445-12-3
2-(4-((3-Propyl-1,2,4-oxadiazol-5-yl)methyl)piperazin-1-yl)ethan-1-ol
CAS 1070445-12-3C12H22N4O2
1-(1-(3-Methyl-1,2,4-oxadiazol-5-yl)ethyl)piperazine chemical structure, C9H16N4O, CAS 1247780-89-7
1-(1-(3-Methyl-1,2,4-oxadiazol-5-yl)ethyl)piperazine
CAS 1247780-89-7C9H16N4O
1-{1-[3-(Propan-2-yl)-1,2,4-oxadiazol-5-yl]ethyl}piperazine chemical structure, C11H20N4O, CAS 1249814-83-2
1-{1-[3-(Propan-2-yl)-1,2,4-oxadiazol-5-yl]ethyl}piperazine
CAS 1249814-83-2C11H20N4O
1-[1-(3-Ethyl-1,2,4-oxadiazol-5-yl)ethyl]piperazine chemical structure, C10H18N4O, CAS 1251101-02-6
1-[1-(3-Ethyl-1,2,4-oxadiazol-5-yl)ethyl]piperazine
CAS 1251101-02-6C10H18N4O
1-{[3-(1-Ethoxyethyl)-1,2,4-oxadiazol-5-yl]methyl}piperazine chemical structure, C11H20N4O2, CAS 1354963-12-4
1-{[3-(1-Ethoxyethyl)-1,2,4-oxadiazol-5-yl]methyl}piperazine
CAS 1354963-12-4C11H20N4O2
2-(4-((3-Ethyl-1,2,4-oxadiazol-5-yl)methyl)piperazin-1-yl)ethan-1-ol chemical structure, C11H20N4O2, CAS 1356778-32-9
2-(4-((3-Ethyl-1,2,4-oxadiazol-5-yl)methyl)piperazin-1-yl)ethan-1-ol
CAS 1356778-32-9C11H20N4O2
1-[[3-(Methoxymethyl)-1,2,4-oxadiazol-5-yl]methyl]piperazine chemical structure, C9H16N4O2, CAS 1239771-52-8
1-[[3-(Methoxymethyl)-1,2,4-oxadiazol-5-yl]methyl]piperazine
CAS 1239771-52-8C9H16N4O2
1-({3-[1-(Ethylsulfanyl)ethyl]-1,2,4-oxadiazol-5-yl}methyl)-4-(prop-2-yn-1-yl)piperazine chemical structure, C14H22N4OS, CAS 1797656-87-1
1-({3-[1-(Ethylsulfanyl)ethyl]-1,2,4-oxadiazol-5-yl}methyl)-4-(prop-2-yn-1-yl)piperazine
CAS 1797656-87-1C14H22N4OS
1-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]piperazine dihydrochloride chemical structure, C8H16Cl2N4O, CAS 1797807-85-2
1-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]piperazine dihydrochloride
CAS 1797807-85-2C8H16Cl2N4O
1-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]piperazine hydrochloride chemical structure, C8H15ClN4O, CAS 1803580-93-9
1-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]piperazine hydrochloride
CAS 1803580-93-9C8H15ClN4O
1-(4-{[3-(Methoxymethyl)-1,2,4-oxadiazol-5-yl]methyl}piperazin-1-yl)prop-2-en-1-one chemical structure, C12H18N4O3, CAS 2109146-18-9
1-(4-{[3-(Methoxymethyl)-1,2,4-oxadiazol-5-yl]methyl}piperazin-1-yl)prop-2-en-1-one
CAS 2109146-18-9C12H18N4O3
1-(4-((3-Isopropyl-1,2,4-oxadiazol-5-yl)methyl)piperazin-1-yl)prop-2-en-1-one chemical structure, C13H20N4O2, CAS 2208882-70-4
1-(4-((3-Isopropyl-1,2,4-oxadiazol-5-yl)methyl)piperazin-1-yl)prop-2-en-1-one
CAS 2208882-70-4C13H20N4O2
1-(4-(1-(3-Methyl-1,2,4-oxadiazol-5-yl)ethyl)piperazin-1-yl)prop-2-en-1-one chemical structure, C12H18N4O2, CAS 2179724-27-5
1-(4-(1-(3-Methyl-1,2,4-oxadiazol-5-yl)ethyl)piperazin-1-yl)prop-2-en-1-one
CAS 2179724-27-5C12H18N4O2
Ethyl 4-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]piperazine-1-carboxylate chemical structure, C11H18N4O3, CAS 2640935-44-8
Ethyl 4-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]piperazine-1-carboxylate
CAS 2640935-44-8C11H18N4O3
2-Chloro-1-(4-((3-(methoxymethyl)-1,2,4-oxadiazol-5-yl)methyl)piperazin-1-yl)propan-1-one chemical structure, C12H19ClN4O3, CAS 2411306-70-0
2-Chloro-1-(4-((3-(methoxymethyl)-1,2,4-oxadiazol-5-yl)methyl)piperazin-1-yl)propan-1-one
CAS 2411306-70-0C12H19ClN4O3
1-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]-4-(2,2,2-trifluoroethyl)piperazine chemical structure, C10H15F3N4O, CAS 2742039-96-7
1-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]-4-(2,2,2-trifluoroethyl)piperazine
CAS 2742039-96-7C10H15F3N4O
1-{[3-(Propan-2-yl)-1,2,4-oxadiazol-5-yl]methyl}-4-(2,2,2-trifluoroethyl)piperazine chemical structure, C12H19F3N4O, CAS 2742021-64-1
1-{[3-(Propan-2-yl)-1,2,4-oxadiazol-5-yl]methyl}-4-(2,2,2-trifluoroethyl)piperazine
CAS 2742021-64-1C12H19F3N4O
2-{4-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]piperazin-1-yl}-N-(propan-2-yl)propanamide chemical structure, C14H25N5O2, CAS 2741897-67-4
2-{4-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]piperazin-1-yl}-N-(propan-2-yl)propanamide
CAS 2741897-67-4C14H25N5O2
1-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]-4-(propane-2-sulfonyl)piperazine chemical structure, C11H20N4O3S, CAS 2742005-64-5
1-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]-4-(propane-2-sulfonyl)piperazine
CAS 2742005-64-5C11H20N4O3S