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Murcko scaffold

N-2-Pyrimidinyl-2-quinazolinamine scaffold

36 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
36
With full pages
8
Scaffold SMILES

c1cnc(Nc2ncc3ccccc3n2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-2-Pyrimidinyl-2-quinazolinamine page
Murcko scaffold c1cnc(Nc2ncc3ccccc3n2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

(4,6-Dimethyl-pyrimidin-2-yl)-(4-methyl-quinazolin-2-yl)-amine chemical structure, C15H15N5, CAS 5734-57-6
(4,6-Dimethyl-pyrimidin-2-yl)-(4-methyl-quinazolin-2-yl)-amine
CAS 5734-57-6C15H15N5
1-[2-(4,8-Dimethyl-quinazolin-2-ylamino)-4-methyl-pyrimidin-5-yl]-ethanone chemical structure, C17H17N5O, CAS 669752-30-1
1-[2-(4,8-Dimethyl-quinazolin-2-ylamino)-4-methyl-pyrimidin-5-yl]-ethanone
CAS 669752-30-1C17H17N5O
4,6-Dimethyl-N-[4-methyl-6-(trifluoromethyl)pyrimidin-2-yl]quinazolin-2-amine chemical structure, C16H14F3N5, CAS 673493-85-1
4,6-Dimethyl-N-[4-methyl-6-(trifluoromethyl)pyrimidin-2-yl]quinazolin-2-amine
CAS 673493-85-1C16H14F3N5
1-[2-(4,7-Dimethyl-quinazolin-2-ylamino)-4-methyl-pyrimidin-5-yl]-ethanone chemical structure, C17H17N5O, CAS 669752-20-9
1-[2-(4,7-Dimethyl-quinazolin-2-ylamino)-4-methyl-pyrimidin-5-yl]-ethanone
CAS 669752-20-9C17H17N5O
N-(4,6-Dimethylpyrimidin-2-yl)-4,7-dimethylquinazolin-2-amine chemical structure, C16H17N5, CAS 352642-62-7
N-(4,6-Dimethylpyrimidin-2-yl)-4,7-dimethylquinazolin-2-amine
CAS 352642-62-7C16H17N5
N-(4,6-Dimethylpyrimidin-2-yl)-6-methoxy-4-methylquinazolin-2-amine chemical structure, C16H17N5O, CAS 332074-06-3
N-(4,6-Dimethylpyrimidin-2-yl)-6-methoxy-4-methylquinazolin-2-amine
CAS 332074-06-3C16H17N5O
N-(4,6-Dimethylpyrimidin-2-yl)-4,6,7-trimethylquinazolin-2-amine chemical structure, C17H19N5, CAS 332074-07-4
N-(4,6-Dimethylpyrimidin-2-yl)-4,6,7-trimethylquinazolin-2-amine
CAS 332074-07-4C17H19N5
N-(4,6-Dimethylpyrimidin-2-yl)-6-ethoxy-4-methylquinazolin-2-amine chemical structure, C17H19N5O, CAS 5738-13-6
N-(4,6-Dimethylpyrimidin-2-yl)-6-ethoxy-4-methylquinazolin-2-amine
CAS 5738-13-6C17H19N5O
5-Acetyl-2-[(6-methoxy-4-methylquinazolin-2-yl)amino]-4,6-dimethylpyrimidine chemical structure, C18H19N5O2, CAS 674353-23-2
5-Acetyl-2-[(6-methoxy-4-methylquinazolin-2-yl)amino]-4,6-dimethylpyrimidine
CAS 674353-23-2C18H19N5O2
1-[2-[(6-Ethyl-4-methylquinazolin-2-yl)amino]-4-methylpyrimidin-5-yl]ethanone chemical structure, C18H19N5O, CAS 669718-62-1
1-[2-[(6-Ethyl-4-methylquinazolin-2-yl)amino]-4-methylpyrimidin-5-yl]ethanone
CAS 669718-62-1C18H19N5O
6-Ethyl-4-methyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine chemical structure, C16H17N5, CAS 669752-75-4
6-Ethyl-4-methyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine
CAS 669752-75-4C16H17N5
4-Methyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine chemical structure, C14H13N5, CAS 708996-31-0
4-Methyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine
CAS 708996-31-0C14H13N5
5-Acetyl-2-[(4,7-dimethylquinazolin-2-yl)amino]-4,6-dimethylpyrimidine chemical structure, C18H19N5O, CAS 669718-66-5
5-Acetyl-2-[(4,7-dimethylquinazolin-2-yl)amino]-4,6-dimethylpyrimidine
CAS 669718-66-5C18H19N5O
5-Acetyl-2-[(6-methoxy-4-methylquinazolin-2-yl)amino]-4-methylpyrimidine chemical structure, C17H17N5O2, CAS 673491-92-4
5-Acetyl-2-[(6-methoxy-4-methylquinazolin-2-yl)amino]-4-methylpyrimidine
CAS 673491-92-4C17H17N5O2
6-Ethoxy-4-methyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine chemical structure, C16H17N5O, CAS 669752-70-9
6-Ethoxy-4-methyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine
CAS 669752-70-9C16H17N5O
1-[4-Methyl-2-[(4,6,7-trimethylquinazolin-2-yl)amino]pyrimidin-5-yl]ethanone chemical structure, C18H19N5O, CAS 669752-25-4
1-[4-Methyl-2-[(4,6,7-trimethylquinazolin-2-yl)amino]pyrimidin-5-yl]ethanone
CAS 669752-25-4C18H19N5O
6-Methoxy-4-methyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine chemical structure, C15H15N5O, CAS 669749-85-3
6-Methoxy-4-methyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine
CAS 669749-85-3C15H15N5O
5-Acetyl-2-[(4,6-dimethylquinazolin-2-yl)amino]-4,6-dimethylpyrimidine chemical structure, C18H19N5O, CAS 669760-75-2
5-Acetyl-2-[(4,6-dimethylquinazolin-2-yl)amino]-4,6-dimethylpyrimidine
CAS 669760-75-2C18H19N5O
Ethyl 2-[(4,7-dimethylquinazolin-2-yl)amino]-4-methylpyrimidine-5-carboxylate chemical structure, C18H19N5O2, CAS 669718-67-6
Ethyl 2-[(4,7-dimethylquinazolin-2-yl)amino]-4-methylpyrimidine-5-carboxylate
CAS 669718-67-6C18H19N5O2
4,6-Dimethyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine chemical structure, C15H15N5, CAS 674812-09-0
4,6-Dimethyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine
CAS 674812-09-0C15H15N5
4,8-Dimethyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine chemical structure, C15H15N5, CAS 669749-80-8
4,8-Dimethyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine
CAS 669749-80-8C15H15N5
6-Methoxy-4-methyl-N-[4-methyl-6-(trifluoromethyl)pyrimidin-2-yl]quinazolin-2-amine chemical structure, C16H14F3N5O, CAS 672339-15-0
6-Methoxy-4-methyl-N-[4-methyl-6-(trifluoromethyl)pyrimidin-2-yl]quinazolin-2-amine
CAS 672339-15-0C16H14F3N5O
5-Acetyl-2-[(4,6-dimethylquinazolin-2-yl)amino]-4-methylpyrimidine chemical structure, C17H17N5O, CAS 674336-70-0
5-Acetyl-2-[(4,6-dimethylquinazolin-2-yl)amino]-4-methylpyrimidine
CAS 674336-70-0C17H17N5O
4,7-Dimethyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine chemical structure, C15H15N5, CAS 669752-65-2
4,7-Dimethyl-N-(4-methylpyrimidin-2-yl)quinazolin-2-amine
CAS 669752-65-2C15H15N5