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Murcko scaffold

2-Thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one scaffold

40 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
40
With full pages
9
Scaffold SMILES

O=c1[nH]c(=S)[nH]c2ncccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one page
Murcko scaffold O=c1[nH]c(=S)[nH]c2ncccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

3-Allyl-2-mercaptopyrido[2,3-d]pyrimidin-4(3H)-one chemical structure, C10H9N3OS, CAS 92663-26-8
3-Allyl-2-mercaptopyrido[2,3-d]pyrimidin-4(3H)-one
CAS 92663-26-8C10H9N3OS
3-(3-Isopropoxypropyl)-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one chemical structure, C13H17N3O2S, CAS 688793-28-4
3-(3-Isopropoxypropyl)-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one
CAS 688793-28-4C13H17N3O2S
2-Mercapto-3-(3-methoxypropyl)pyrido[2,3-d]pyrimidin-4(3H)-one chemical structure, C11H13N3O2S, CAS 688793-21-7
2-Mercapto-3-(3-methoxypropyl)pyrido[2,3-d]pyrimidin-4(3H)-one
CAS 688793-21-7C11H13N3O2S
3-(3-Ethoxypropyl)-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one chemical structure, C12H15N3O2S, CAS 688793-26-2
3-(3-Ethoxypropyl)-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one
CAS 688793-26-2C12H15N3O2S
3-Pentyl-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one chemical structure, C12H15N3OS, CAS 688793-12-6
3-Pentyl-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one
CAS 688793-12-6C12H15N3OS
3-(2-Methoxyethyl)-2-sulfanyl-3H,4H-pyrido[2,3-d]pyrimidin-4-one chemical structure, C10H11N3O2S, CAS 688793-17-1
3-(2-Methoxyethyl)-2-sulfanyl-3H,4H-pyrido[2,3-d]pyrimidin-4-one
CAS 688793-17-1C10H11N3O2S
3-Butyl-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one chemical structure, C11H13N3OS, CAS 128921-99-3
3-Butyl-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one
CAS 128921-99-3C11H13N3OS
2-(4-Oxo-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-3-yl)-N-prop-2-enylacetamide chemical structure, C12H12N4O2S, CAS 688793-64-8
2-(4-Oxo-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-3-yl)-N-prop-2-enylacetamide
CAS 688793-64-8C12H12N4O2S
N-(3-Methylbutyl)-2-(4-oxo-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-3-yl)acetamide chemical structure, C14H18N4O2S, CAS 688793-66-0
N-(3-Methylbutyl)-2-(4-oxo-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-3-yl)acetamide
CAS 688793-66-0C14H18N4O2S
2-(4-Oxo-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-3-yl)acetic acid chemical structure, C9H7N3O3S, CAS 128922-04-3
2-(4-Oxo-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-3-yl)acetic acid
CAS 128922-04-3C9H7N3O3S
3-[2-[Butyl(methyl)amino]ethyl]-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-4-one chemical structure, C14H20N4OS, CAS 688793-34-2
3-[2-[Butyl(methyl)amino]ethyl]-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-4-one
CAS 688793-34-2C14H20N4OS
N-[2-(4-Oxo-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-3-yl)ethyl]acetamide chemical structure, C11H12N4O2S, CAS 688793-24-0
N-[2-(4-Oxo-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-3-yl)ethyl]acetamide
CAS 688793-24-0C11H12N4O2S
3-(2-(Diethylamino)ethyl)-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one chemical structure, C13H18N4OS, CAS 896707-60-1
3-(2-(Diethylamino)ethyl)-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one
CAS 896707-60-1C13H18N4OS
3-[2-(Dimethylamino)ethyl]-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one chemical structure, C11H14N4OS, CAS 688793-20-6
3-[2-(Dimethylamino)ethyl]-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one
CAS 688793-20-6C11H14N4OS
3-(2-Ethylhexyl)-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-4-one chemical structure, C15H21N3OS, CAS 443671-60-1
3-(2-Ethylhexyl)-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-4-one
CAS 443671-60-1C15H21N3OS
N-(2-Ethylhexyl)-2-(4-oxo-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-3-yl)acetamide chemical structure, C17H24N4O2S, CAS 688793-68-2
N-(2-Ethylhexyl)-2-(4-oxo-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-3-yl)acetamide
CAS 688793-68-2C17H24N4O2S
2-Mercapto-5,7-dimethyl-pyrido[2,3-d]pyrimidin-4-ol chemical structure, C9H9N3OS, CAS 49600-56-8
2-Mercapto-5,7-dimethyl-pyrido[2,3-d]pyrimidin-4-ol
CAS 49600-56-8C9H9N3OS
Methyl 7-isopropyl-2-mercapto-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidine-5-carboxylate chemical structure, C12H13N3O3S, CAS 885461-05-2
Methyl 7-isopropyl-2-mercapto-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidine-5-carboxylate
CAS 885461-05-2C12H13N3O3S
Methyl 7-methyl-4-oxo-2-sulfanyl-3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate chemical structure, C10H9N3O3S, CAS 885524-05-0
Methyl 7-methyl-4-oxo-2-sulfanyl-3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate
CAS 885524-05-0C10H9N3O3S
2-Thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one chemical structure, C7H5N3OS, CAS 37891-04-6
2-Thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one
CAS 37891-04-6C7H5N3OS
2-Mercapto-1-methylpyrido[2,3-d]pyrimidin-4(1H)-one chemical structure, C8H7N3OS, CAS 89374-52-7
2-Mercapto-1-methylpyrido[2,3-d]pyrimidin-4(1H)-one
CAS 89374-52-7C8H7N3OS
1-Ethyl-2,3-dihydro-2-thioxopyrido[2,3-d]pyrimidin-4(1H)-one chemical structure, C9H9N3OS, CAS 89374-53-8
1-Ethyl-2,3-dihydro-2-thioxopyrido[2,3-d]pyrimidin-4(1H)-one
CAS 89374-53-8C9H9N3OS
3-Ethyl-2-sulfanyl-3H,4H-pyrido(2,3-d)pyrimidin-4-one chemical structure, C9H9N3OS, CAS 923164-38-9
3-Ethyl-2-sulfanyl-3H,4H-pyrido(2,3-d)pyrimidin-4-one
CAS 923164-38-9C9H9N3OS
3-Isobutyl-2-mercaptopyrido[2,3-d]pyrimidin-4(3H)-one chemical structure, C11H13N3OS, CAS 929975-07-5
3-Isobutyl-2-mercaptopyrido[2,3-d]pyrimidin-4(3H)-one
CAS 929975-07-5C11H13N3OS