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Murcko scaffold

Ring system with 2 rings and 10 atoms

52 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
52
With full pages
4
Scaffold SMILES

c1nc(C2CCCC2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nc(C2CCCC2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 52 chemicals

2-(4-Cyclopentyl-1,3-thiazol-2-yl)acetic acid chemical structure, C10H13NO2S, CAS 898382-24-6
2-(4-Cyclopentyl-1,3-thiazol-2-yl)acetic acid
CAS 898382-24-6C10H13NO2S
Methyl 3-(2-guanidinothiazol-4-yl)cyclopentane carboxylate chemical structure, C11H16N4O2S, CAS 84545-71-1
Methyl 3-(2-guanidinothiazol-4-yl)cyclopentane carboxylate
CAS 84545-71-1C11H16N4O2S
tert-Butyl (1-(2-aminothiazol-4-yl)cyclopentyl)carbamate chemical structure, C13H21N3O2S, CAS 921613-26-5
tert-Butyl (1-(2-aminothiazol-4-yl)cyclopentyl)carbamate
CAS 921613-26-5C13H21N3O2S
2-Bromo-4-cyclopentyl-1,3-thiazole chemical structure, C8H10BrNS, CAS 1159814-15-9
2-Bromo-4-cyclopentyl-1,3-thiazole
CAS 1159814-15-9C8H10BrNS
4-Cyclopentylthiazol-2-amine chemical structure, C8H12N2S, CAS 936-34-5
4-Cyclopentylthiazol-2-amine
CAS 936-34-5C8H12N2S
4-Cyclopentyl-1,3-thiazol-5-amine chemical structure, C8H12N2S, CAS 1249801-80-6
4-Cyclopentyl-1,3-thiazol-5-amine
CAS 1249801-80-6C8H12N2S
Ethyl 2-(4-cyclopentyl-1,3-thiazol-2-yl)acetate chemical structure, C12H17NO2S, CAS 1250083-19-2
Ethyl 2-(4-cyclopentyl-1,3-thiazol-2-yl)acetate
CAS 1250083-19-2C12H17NO2S
5-Bromo-4-(cyclopentyl)thiazole chemical structure, C8H10BrNS, CAS 1243838-92-7
5-Bromo-4-(cyclopentyl)thiazole
CAS 1243838-92-7C8H10BrNS
2,5-Dibromo-4-(cyclopentyl)thiazole chemical structure, C8H9Br2NS, CAS 1314355-79-7
2,5-Dibromo-4-(cyclopentyl)thiazole
CAS 1314355-79-7C8H9Br2NS
1-(2-Methyl-1,3-thiazol-4-yl)cyclopentane-1-carboxylic acid chemical structure, C10H13NO2S, CAS 1483713-17-2
1-(2-Methyl-1,3-thiazol-4-yl)cyclopentane-1-carboxylic acid
CAS 1483713-17-2C10H13NO2S
1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclopentane-1-carboxylic acid chemical structure, C12H17NO2S, CAS 1505441-86-0
1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclopentane-1-carboxylic acid
CAS 1505441-86-0C12H17NO2S
Methyl 2-amino-4-cyclopentyl-1,3-thiazole-5-carboxylate chemical structure, C10H14N2O2S, CAS 1461705-01-0
Methyl 2-amino-4-cyclopentyl-1,3-thiazole-5-carboxylate
CAS 1461705-01-0C10H14N2O2S
4-Cyclopentyl-1,3-thiazole-5-carboxylic acid chemical structure, C9H11NO2S, CAS 1461706-86-4
4-Cyclopentyl-1,3-thiazole-5-carboxylic acid
CAS 1461706-86-4C9H11NO2S
tert-Butyl N-(4-cyclopentyl-1,3-thiazol-5-yl)carbamate chemical structure, C13H20N2O2S, CAS 1461706-90-0
tert-Butyl N-(4-cyclopentyl-1,3-thiazol-5-yl)carbamate
CAS 1461706-90-0C13H20N2O2S
4-Cyclopentyl-1,3-thiazol-5-amine dihydrochloride chemical structure, C8H14Cl2N2S, CAS 1461708-28-0
4-Cyclopentyl-1,3-thiazol-5-amine dihydrochloride
CAS 1461708-28-0C8H14Cl2N2S
N-(Cyanomethyl)-4-cyclopentyl-N-(propan-2-yl)-1,3-thiazole-5-carboxamide chemical structure, C14H19N3OS, CAS 1797383-45-9
N-(Cyanomethyl)-4-cyclopentyl-N-(propan-2-yl)-1,3-thiazole-5-carboxamide
CAS 1797383-45-9C14H19N3OS
N-(1-Cyano-2-methoxy-1-methylethyl)-4-cyclopentyl-1,3-thiazole-5-carboxamide chemical structure, C14H19N3O2S, CAS 1797366-41-6
N-(1-Cyano-2-methoxy-1-methylethyl)-4-cyclopentyl-1,3-thiazole-5-carboxamide
CAS 1797366-41-6C14H19N3O2S
4-Cyclopentyl-N-(prop-2-ene-1-sulfonyl)-1,3-thiazole-5-carboxamide chemical structure, C12H16N2O3S2, CAS 1797983-24-4
4-Cyclopentyl-N-(prop-2-ene-1-sulfonyl)-1,3-thiazole-5-carboxamide
CAS 1797983-24-4C12H16N2O3S2
1-(1,3-Thiazol-4-yl)cyclopentan-1-amine chemical structure, C8H12N2S, CAS 1521465-28-0
1-(1,3-Thiazol-4-yl)cyclopentan-1-amine
CAS 1521465-28-0C8H12N2S
1-(2-Methyl-1,3-thiazol-4-yl)cyclopentan-1-amine chemical structure, C9H14N2S, CAS 1520545-18-9
1-(2-Methyl-1,3-thiazol-4-yl)cyclopentan-1-amine
CAS 1520545-18-9C9H14N2S
1-[1-(1,3-Thiazol-4-yl)cyclopentyl]methanamine chemical structure, C9H14N2S, CAS 1526700-97-9
1-[1-(1,3-Thiazol-4-yl)cyclopentyl]methanamine
CAS 1526700-97-9C9H14N2S
1-[1-(2-Methyl-1,3-thiazol-4-yl)cyclopentyl]methanamine chemical structure, C10H16N2S, CAS 1522976-02-8
1-[1-(2-Methyl-1,3-thiazol-4-yl)cyclopentyl]methanamine
CAS 1522976-02-8C10H16N2S
1-(1,3-Thiazol-4-yl)cyclopentane-1-carboxylic acid chemical structure, C9H11NO2S, CAS 1512265-78-9
1-(1,3-Thiazol-4-yl)cyclopentane-1-carboxylic acid
CAS 1512265-78-9C9H11NO2S
1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclopentan-1-amine chemical structure, C11H18N2S, CAS 1533836-88-2
1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclopentan-1-amine
CAS 1533836-88-2C11H18N2S