Murcko scaffold
N-Benzylpyridine-2-carboxamide scaffold
138 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 138
- With full pages
- 4
Scaffold SMILES
O=C(NCc1ccccc1)c1ccccn1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 138 chemicals
N-(1-Phenylethyl)-2-pyridinecarboxamide
CAS 2909-32-2C14H14N2O
N-Benzylpyridine-2-carboxamide
CAS 18904-38-6C13H12N2O
![2-Pyridinecarboxamide, N-[(1R)-1-phenylethyl]- chemical structure, C14H14N2O, CAS 668461-31-2](/s/HSECEQYULBGNJA-LLVKDONJSA-N.svg)
2-Pyridinecarboxamide, N-[(1R)-1-phenylethyl]-
CAS 668461-31-2C14H14N2O
![N-[(4-Methoxyphenyl)methyl]pyridine-2-carboxamide chemical structure, C14H14N2O2, CAS 77250-70-5](/s/DXONIXQBQWIJMK-UHFFFAOYSA-N.svg)
N-[(4-Methoxyphenyl)methyl]pyridine-2-carboxamide
CAS 77250-70-5C14H14N2O2
![N-[(4-Methylphenyl)methyl]pyridine-2-carboxamide chemical structure, C14H14N2O, CAS 795283-79-3](/s/IPQGJKYDPVNOEO-UHFFFAOYSA-N.svg)
N-[(4-Methylphenyl)methyl]pyridine-2-carboxamide
CAS 795283-79-3C14H14N2O
N-(2-Methoxybenzyl)picolinamide
CAS 867350-21-8C14H14N2O2
![N-[(4-Fluorophenyl)methyl]pyridine-2-carboxamide chemical structure, C13H11FN2O, CAS 803694-10-2](/s/NZNPYKWNAVHQQQ-UHFFFAOYSA-N.svg)
N-[(4-Fluorophenyl)methyl]pyridine-2-carboxamide
CAS 803694-10-2C13H11FN2O
N-Benzyl-3,6-dichloropyridine-2-carboxamide
CAS 852916-60-0C13H10Cl2N2O
![N-[(4-Chlorophenyl)methyl]pyridine-2-carboxamide chemical structure, C13H11ClN2O, CAS 77250-71-6](/s/CJNIVNCTCNIRSY-UHFFFAOYSA-N.svg)
N-[(4-Chlorophenyl)methyl]pyridine-2-carboxamide
CAS 77250-71-6C13H11ClN2O
![3,6-Dichloro-N-[(4-chlorophenyl)methyl]pyridine-2-carboxamide chemical structure, C13H9Cl3N2O, CAS 852850-81-8](/s/OITAFIZCJMHXRJ-UHFFFAOYSA-N.svg)
3,6-Dichloro-N-[(4-chlorophenyl)methyl]pyridine-2-carboxamide
CAS 852850-81-8C13H9Cl3N2O
N-(1-(2,4-Dichlorophenyl)ethyl)picolinamide
CAS 2014367-95-2C14H12Cl2N2O
3-Hydroxy-N-(phenylmethyl)-2-Pyridinecarboxamide
CAS 1022-50-0C13H12N2O2
3-Hydroxy-N-(p-tolylmethyl)pyridine-2-carboxamide
CAS 1086-63-1C14H14N2O2
![2-Pyridinecarboxamide,N-[(4-chlorophenyl)methyl]-3-hydroxy- chemical structure, C13H11ClN2O2, CAS 1025-67-8](/s/GMFVAAGYFUIKAV-UHFFFAOYSA-N.svg)
2-Pyridinecarboxamide,N-[(4-chlorophenyl)methyl]-3-hydroxy-
CAS 1025-67-8C13H11ClN2O2
![2-Pyridinecarboxamide,N-[(3,4-dichlorophenyl)methyl]-3-hydroxy- chemical structure, C13H10Cl2N2O2, CAS 1088-51-3](/s/FCXXZGQDDLXVAQ-UHFFFAOYSA-N.svg)
2-Pyridinecarboxamide,N-[(3,4-dichlorophenyl)methyl]-3-hydroxy-
CAS 1088-51-3C13H10Cl2N2O2
![3-Hydroxy-N-[(4-nitrophenyl)methyl]pyridine-2-carboxamide chemical structure, C13H11N3O4, CAS 1032-85-5](/s/SQNCKXYKQQPHPO-UHFFFAOYSA-N.svg)
3-Hydroxy-N-[(4-nitrophenyl)methyl]pyridine-2-carboxamide
CAS 1032-85-5C13H11N3O4
![3-Hydroxy-N-[(3-nitrophenyl)methyl]pyridine-2-carboxamide chemical structure, C13H11N3O4, CAS 3373-02-2](/s/SOFBUERKXAVDMZ-UHFFFAOYSA-N.svg)
3-Hydroxy-N-[(3-nitrophenyl)methyl]pyridine-2-carboxamide
CAS 3373-02-2C13H11N3O4
4-Chloro-N-(4-methoxybenzyl)picolinamide
CAS 923762-04-3C14H13ClN2O2
4-Chloro-N-(4-fluorobenzyl)picolinamide
CAS 851441-84-4C13H10ClFN2O
Picolinic acid 2-chlorobenzylamide
CAS 923229-50-9C13H11ClN2O
![3,6-Dichloro-N-[(2-methoxyphenyl)methyl]pyridine-2-carboxamide chemical structure, C14H12Cl2N2O2, CAS 873891-45-3](/s/YJWWWBZJKFVOMD-UHFFFAOYSA-N.svg)
3,6-Dichloro-N-[(2-methoxyphenyl)methyl]pyridine-2-carboxamide
CAS 873891-45-3C14H12Cl2N2O2
![Methyl 4-{[(3,6-dichloropyridin-2-yl)formamido]methyl}benzoate chemical structure, C15H12Cl2N2O3, CAS 872096-38-3](/s/UZXZXLMJAIUGSI-UHFFFAOYSA-N.svg)
Methyl 4-{[(3,6-dichloropyridin-2-yl)formamido]methyl}benzoate
CAS 872096-38-3C15H12Cl2N2O3
![3,6-Dichloro-N-({2-[(dimethylamino)methyl]phenyl}methyl)pyridine-2-carboxamide chemical structure, C16H17Cl2N3O, CAS 872456-02-5](/s/SBKIDAYFVIPVMI-UHFFFAOYSA-N.svg)
3,6-Dichloro-N-({2-[(dimethylamino)methyl]phenyl}methyl)pyridine-2-carboxamide
CAS 872456-02-5C16H17Cl2N3O
![3,6-Dichloro-N-[(3,4-dimethoxyphenyl)methyl]pyridine-2-carboxamide chemical structure, C15H14Cl2N2O3, CAS 873809-97-3](/s/ZIXBWPAQEAZWBS-UHFFFAOYSA-N.svg)
3,6-Dichloro-N-[(3,4-dimethoxyphenyl)methyl]pyridine-2-carboxamide
CAS 873809-97-3C15H14Cl2N2O3
- N-[(2-Methylphenyl)methyl]pyridine-2-carboxamide867350-26-3C14H14N2O
- 4-Chloro-N-(2-chlorobenzyl)picolinamide923775-59-1C13H10Cl2N2O
- Methyl 4-{[(pyridin-2-yl)formamido]methyl}benzoate879190-14-4C15H14N2O3
- 2-(Benzylcarbamoyl)pyridine-3-carboxylic acid100872-65-9C14H12N2O3
- 4-Amino-5-cyano-N-[(2,4-dimethylphenyl)methyl]-6-ethoxy-2-pyridinecarboxamide904310-73-2C18H20N4O2
- 2-Pyridinecarboxamide, 4-amino-5-cyano-6-ethoxy-N-[[4-(methylsulfonyl)phenyl]methyl]-904311-34-8C17H18N4O4S
- 4-Amino-5-cyano-6-ethoxy-N-[(2-sulfamoylphenyl)methyl]pyridine-2-carboxamide904311-05-3C16H17N5O4S
- 4-Amino-5-chloro-6-ethoxy-N-(4-(methylsulfonyl)benzyl)picolinamide904311-45-1C16H18ClN3O4S
- 3,4,5,6-Tetrachloro-N-methyl-N-[1-(3-nitrophenyl)ethyl]pyridine-2-carboxamide926747-78-6C15H11Cl4N3O3
- 3,6-Dichloro-N-[1-(2-methoxyphenyl)ethyl]pyridine-2-carboxamide930664-03-2C15H14Cl2N2O2
- 3,6-Dichloro-N-[(3-chlorophenyl)methyl]-N-methylpyridine-2-carboxamide930986-39-3C14H11Cl3N2O
- 3,6-Dichloro-N-[1-(4-fluorophenyl)ethyl]pyridine-2-carboxamide931004-46-5C14H11Cl2FN2O
- Ethyl 2-(4-chlorophenyl)-2-[1-(3,6-dichloropyridin-2-yl)-N-ethylformamido]acetate1103631-46-4C18H17Cl3N2O3
- 1 suppliersN-Benzyl-4-chloropyridine-2-carboxamide116275-39-9C13H11ClN2O
- N-{[4-(Trifluoromethyl)phenyl]methyl}pyridine-2-carboxamide1015360-82-3C14H11F3N2O
- N-Benzyl-6-chloropyridine-2-carboxamide149527-04-8C13H11ClN2O
- 1 suppliersN-Benzyl-5-bromopicolinamide951885-05-5C13H11BrN2O
- 5-Bromo-N-(4-methoxybenzyl)pyridine-2-carboxamide951885-02-2C14H13BrN2O2
- 3,6-Dichloro-N-[(4-methylphenyl)methyl]pyridine-2-carboxamide1021122-41-7C14H12Cl2N2O
- 3,4,5,6-Tetrachloro-N-methyl-N-{[4-(methylcarbamoyl)phenyl]methyl}pyridine-2-carboxamide1223027-28-8C16H13Cl4N3O2
- N-({2-[(Dimethylamino)methyl]phenyl}methyl)pyridine-2-carboxamide1210871-97-8C16H19N3O
- N-[(3-Carbamoylphenyl)methyl]-3,6-dichloropyridine-2-carboxamide1307460-72-5C14H11Cl2N3O2
- 3,4,5,6-Tetrachloro-N-[(2,5-dimethoxyphenyl)methyl]pyridine-2-carboxamide1241304-82-4C15H12Cl4N2O3
- N-[(3-Methylphenyl)methyl]pyridine-2-carboxamide867350-27-4C14H14N2O
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)Nc1ccccc1421 chemicals
O=C(C=Cc1ccccc1)c1ccccc1389 chemicals
O=C(NCc1ccccc1)c1ccccc1260 chemicals
O=C(Cc1ccccc1)Nc1ccccc1219 chemicals
O=S(=O)(NCc1ccccc1)c1ccccc1164 chemicals
c1ccc(CNCc2ccccc2)cc1142 chemicals
S=C(Nc1ccccc1)Nc1ccccc1109 chemicals
O=C(CCc1ccccc1)c1ccccc187 chemicals
C(=NNc1ccccc1)c1ccccc173 chemicals
O=C(Nc1ccccc1)Oc1ccccc173 chemicals
O=C(OCc1ccccc1)N1CCCCC161 chemicals
O=C(OCc1ccccc1)c1ccccc157 chemicals