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Murcko scaffold

Ring system with 2 rings and 12 atoms

11 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
11
With full pages
3
Scaffold SMILES

O=c1ncccn1C1COCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ncccn1C1COCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

Bch 4556 chemical structure, C8H11N3O4, CAS 141196-85-2
Bch 4556
CAS 141196-85-2C8H11N3O4
4-Amino-1-[2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one chemical structure, C8H11N3O4, CAS 908827-81-6
4-Amino-1-[2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one
CAS 908827-81-6C8H11N3O4
4-Amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one chemical structure, C8H11N3O4, CAS 141196-84-1
4-Amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one
CAS 141196-84-1C8H11N3O4
Troxacitabine chemical structure, C8H11N3O4, CAS 145918-75-8
Troxacitabine
CAS 145918-75-8C8H11N3O4
4-Amino-5-fluoro-1-[(2R,4R)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one chemical structure, C8H10FN3O4, CAS 145417-33-0
4-Amino-5-fluoro-1-[(2R,4R)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one
CAS 145417-33-0C8H10FN3O4
4-Amino-1-[(2S,4R)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one chemical structure, C8H11N3O4, CAS 145416-37-1
4-Amino-1-[(2S,4R)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one
CAS 145416-37-1C8H11N3O4
alpha-L-(+)-(2S,4R)-1-(2-(Hydroxymethyl)-1,3-dioxolan-4-yl)-5-fluorocytosine chemical structure, C8H10FN3O4, CAS 147060-42-2
alpha-L-(+)-(2S,4R)-1-(2-(Hydroxymethyl)-1,3-dioxolan-4-yl)-5-fluorocytosine
CAS 147060-42-2C8H10FN3O4
5-Fhmed-cytosine chemical structure, C8H10FN3O4, CAS 145397-26-8
5-Fhmed-cytosine
CAS 145397-26-8C8H10FN3O4
Troxacitabine monophosphate chemical structure, C8H12N3O7P, CAS 182482-78-6
Troxacitabine monophosphate
CAS 182482-78-6C8H12N3O7P
Troxacitabine triphosphate chemical structure, C8H14N3O13P3, CAS 171039-00-2
Troxacitabine triphosphate
CAS 171039-00-2C8H14N3O13P3
L-OddCDP chemical structure, C8H13N3O10P2, CAS 182482-79-7
L-OddCDP
CAS 182482-79-7C8H13N3O10P2