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Murcko scaffold

4-(2-Naphthyl)-1,3-thiazole scaffold

32 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
32
With full pages
5
Scaffold SMILES

c1ccc2cc(-c3cscn3)ccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(2-Naphthyl)-1,3-thiazole page
Murcko scaffold c1ccc2cc(-c3cscn3)ccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

N-(4-Naphthalen-2-yl-1,3-thiazol-2-yl)acetamide chemical structure, C15H12N2OS, CAS 7496-78-8
N-(4-Naphthalen-2-yl-1,3-thiazol-2-yl)acetamide
CAS 7496-78-8C15H12N2OS
4-(2-Naphthyl)-1,3-thiazol-2-amine chemical structure, C13H10N2S, CAS 21331-43-1
4-(2-Naphthyl)-1,3-thiazol-2-amine
CAS 21331-43-1C13H10N2S
2-Methyl-4-(2-naphthyl)-1,3-thiazole chemical structure, C14H11NS, CAS 57493-25-1
2-Methyl-4-(2-naphthyl)-1,3-thiazole
CAS 57493-25-1C14H11NS
2-[4-(Naphthalen-2-yl)-1,3-thiazol-2-yl]acetonitrile chemical structure, C15H10N2S, CAS 194809-95-5
2-[4-(Naphthalen-2-yl)-1,3-thiazol-2-yl]acetonitrile
CAS 194809-95-5C15H10N2S
Ethyl (2E)-4-{[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]amino}-4-oxobut-2-enoate chemical structure, C19H16N2O3S, CAS 314289-95-7
Ethyl (2E)-4-{[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]amino}-4-oxobut-2-enoate
CAS 314289-95-7C19H16N2O3S
3-Acetamido-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)propanamide chemical structure, C18H17N3O2S, CAS 851206-44-5
3-Acetamido-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)propanamide
CAS 851206-44-5C18H17N3O2S
4-(Naphthalen-2-yl)thiazole-2-carbaldehyde chemical structure, C14H9NOS, CAS 383140-93-0
4-(Naphthalen-2-yl)thiazole-2-carbaldehyde
CAS 383140-93-0C14H9NOS
N-(4-(Naphthalen-2-yl)thiazol-2-yl)pentanamide chemical structure, C18H18N2OS, CAS 321555-27-5
N-(4-(Naphthalen-2-yl)thiazol-2-yl)pentanamide
CAS 321555-27-5C18H18N2OS
Diethyl 2-({[4-(2-naphthyl)-1,3-thiazol-2-yl]amino}methylene)malonate chemical structure, C21H20N2O4S, CAS 478258-62-7
Diethyl 2-({[4-(2-naphthyl)-1,3-thiazol-2-yl]amino}methylene)malonate
CAS 478258-62-7C21H20N2O4S
4-(6-Methoxy-2-naphthyl)-1,3-thiazol-2-amine chemical structure, C14H12N2OS, CAS 195824-61-4
4-(6-Methoxy-2-naphthyl)-1,3-thiazol-2-amine
CAS 195824-61-4C14H12N2OS
N-(4-Naphthalen-2-yl-1,3-thiazol-2-yl)hexanamide chemical structure, C19H20N2OS, CAS 353764-73-5
N-(4-Naphthalen-2-yl-1,3-thiazol-2-yl)hexanamide
CAS 353764-73-5C19H20N2OS
N-(4-(Naphthalen-2-yl)thiazol-2-yl)isobutyramide chemical structure, C17H16N2OS, CAS 313549-63-2
N-(4-(Naphthalen-2-yl)thiazol-2-yl)isobutyramide
CAS 313549-63-2C17H16N2OS
(4-(Naphthalen-2-yl)thiazol-2-yl)methanamine chemical structure, C14H12N2S, CAS 643723-52-8
(4-(Naphthalen-2-yl)thiazol-2-yl)methanamine
CAS 643723-52-8C14H12N2S
4-(2-Naphthyl)-1,3-thiazole chemical structure, C13H9NS, CAS 96461-06-2
4-(2-Naphthyl)-1,3-thiazole
CAS 96461-06-2C13H9NS
(E)-4-[(4-Naphthalen-2-yl-1,3-thiazol-2-yl)amino]-4-oxobut-2-enoic acid chemical structure, C17H12N2O3S, CAS 329078-08-2
(E)-4-[(4-Naphthalen-2-yl-1,3-thiazol-2-yl)amino]-4-oxobut-2-enoic acid
CAS 329078-08-2C17H12N2O3S
Ethyl (2E)-2-cyano-3-{[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]amino}prop-2-enoate chemical structure, C19H15N3O2S, CAS 478258-32-1
Ethyl (2E)-2-cyano-3-{[4-(naphthalen-2-yl)-1,3-thiazol-2-yl]amino}prop-2-enoate
CAS 478258-32-1C19H15N3O2S
2-Hydrazinyl-4-(6-methoxynaphthalen-2-yl)thiazole chemical structure, C14H13N3OS, CAS 886495-56-3
2-Hydrazinyl-4-(6-methoxynaphthalen-2-yl)thiazole
CAS 886495-56-3C14H13N3OS
2-Hydrazinyl-4-(naphthalen-2-yl)thiazole chemical structure, C13H11N3S, CAS 299439-90-0
2-Hydrazinyl-4-(naphthalen-2-yl)thiazole
CAS 299439-90-0C13H11N3S
N-Methyl-4-(naphthalen-2-yl)-1,3-thiazol-2-amine chemical structure, C14H12N2S, CAS 21331-44-2
N-Methyl-4-(naphthalen-2-yl)-1,3-thiazol-2-amine
CAS 21331-44-2C14H12N2S
1-[4-(Naphthalen-2-yl)-1,3-thiazol-2-yl]guanidine chemical structure, C14H12N4S, CAS 733722-57-1
1-[4-(Naphthalen-2-yl)-1,3-thiazol-2-yl]guanidine
CAS 733722-57-1C14H12N4S
4-(Naphthalen-2-yl)thiazole-2-carboxylic acid chemical structure, C14H9NO2S, CAS 488816-60-0
4-(Naphthalen-2-yl)thiazole-2-carboxylic acid
CAS 488816-60-0C14H9NO2S
Ethyl 4-(2-naphthyl)-1,3-thiazole-2-carboxylate chemical structure, C16H13NO2S, CAS 338760-31-9
Ethyl 4-(2-naphthyl)-1,3-thiazole-2-carboxylate
CAS 338760-31-9C16H13NO2S
2-Methyl-4-(2-naphthalenyl)-5-thiazolecarboxylic acid ethyl ester chemical structure, C17H15NO2S, CAS 330803-43-5
2-Methyl-4-(2-naphthalenyl)-5-thiazolecarboxylic acid ethyl ester
CAS 330803-43-5C17H15NO2S
2-Chloro-4-(naphthalen-2-yl)thiazole chemical structure, C13H8ClNS, CAS 1049126-52-4
2-Chloro-4-(naphthalen-2-yl)thiazole
CAS 1049126-52-4C13H8ClNS