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Murcko scaffold

Ring system with 3 rings and 26 atoms

25 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 26
Chemicals: 25
With full pages: 3

Scaffold SMILES

O=C(Nc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

1-(4-Chlorophenyl)-3-[4-[(4-fluorophenyl)sulfamoyl]phenyl]urea chemical structure, C19H15ClFN3O3S, CAS 327067-80-1

1-(4-Chlorophenyl)-3-[4-[(4-fluorophenyl)sulfamoyl]phenyl]urea

CAS 327067-80-1C₁₉H₁₅ClFN₃O₃S

4-[(Anilinocarbonyl)amino]-N-(4-fluorophenyl)benzenesulfonamide chemical structure, C19H16FN3O3S, CAS 349470-56-0

4-[(Anilinocarbonyl)amino]-N-(4-fluorophenyl)benzenesulfonamide

CAS 349470-56-0C₁₉H₁₆FN₃O₃S

1-[4-[(4-Iodophenyl)sulfamoyl]phenyl]-3-phenylurea chemical structure, C19H16IN3O3S, CAS 433258-80-1

1-[4-[(4-Iodophenyl)sulfamoyl]phenyl]-3-phenylurea

CAS 433258-80-1C₁₉H₁₆IN₃O₃S

1-(4-Chlorophenyl)-3-[4-[(4-ethoxyphenyl)sulfamoyl]phenyl]urea chemical structure, C21H20ClN3O4S, CAS 458553-83-8

1-(4-Chlorophenyl)-3-[4-[(4-ethoxyphenyl)sulfamoyl]phenyl]urea

CAS 458553-83-8C₂₁H₂₀ClN₃O₄S

4-[(Anilinocarbonyl)amino]-N-(4-ethoxyphenyl)benzenesulfonamide chemical structure, C21H21N3O4S, CAS 433323-65-0

4-[(Anilinocarbonyl)amino]-N-(4-ethoxyphenyl)benzenesulfonamide

CAS 433323-65-0C₂₁H₂₁N₃O₄S

1-[4-[Ethyl(phenyl)sulfamoyl]phenyl]-3-phenylurea chemical structure, C21H21N3O3S, CAS 650575-68-1

1-[4-[Ethyl(phenyl)sulfamoyl]phenyl]-3-phenylurea

CAS 650575-68-1C₂₁H₂₁N₃O₃S

1-(4-Chlorophenyl)-3-[4-[ethyl(phenyl)sulfamoyl]phenyl]urea chemical structure, C21H20ClN3O3S, CAS 650575-59-0

1-(4-Chlorophenyl)-3-[4-[ethyl(phenyl)sulfamoyl]phenyl]urea

CAS 650575-59-0C₂₁H₂₀ClN₃O₃S

1-(4-Chlorophenyl)-3-[4-[(3,4-dimethylphenyl)sulfamoyl]phenyl]urea chemical structure, C21H20ClN3O3S, CAS 650622-05-2

1-(4-Chlorophenyl)-3-[4-[(3,4-dimethylphenyl)sulfamoyl]phenyl]urea

CAS 650622-05-2C₂₁H₂₀ClN₃O₃S

1-(4-Chlorophenyl)-3-[4-[(4-methoxyphenyl)sulfamoyl]phenyl]urea chemical structure, C20H18ClN3O4S, CAS 433974-63-1

1-(4-Chlorophenyl)-3-[4-[(4-methoxyphenyl)sulfamoyl]phenyl]urea

CAS 433974-63-1C₂₀H₁₈ClN₃O₄S

1-(3-Chlorophenyl)-3-[4-[(4-ethoxyphenyl)sulfamoyl]phenyl]urea chemical structure, C21H20ClN3O4S, CAS 791791-46-3

1-(3-Chlorophenyl)-3-[4-[(4-ethoxyphenyl)sulfamoyl]phenyl]urea

CAS 791791-46-3C₂₁H₂₀ClN₃O₄S

1-(3-Chlorophenyl)-3-[4-[ethyl(phenyl)sulfamoyl]phenyl]urea chemical structure, C21H20ClN3O3S, CAS 712318-50-8

1-(3-Chlorophenyl)-3-[4-[ethyl(phenyl)sulfamoyl]phenyl]urea

CAS 712318-50-8C₂₁H₂₀ClN₃O₃S

1-(3-Chlorophenyl)-3-[4-(phenylsulfamoyl)phenyl]urea chemical structure, C19H16ClN3O3S, CAS 712318-51-9

1-(3-Chlorophenyl)-3-[4-(phenylsulfamoyl)phenyl]urea

CAS 712318-51-9C₁₉H₁₆ClN₃O₃S

1-[4-[Methyl(phenyl)sulfamoyl]phenyl]-3-phenylurea chemical structure, C20H19N3O3S, CAS 714278-79-2

1-[4-[Methyl(phenyl)sulfamoyl]phenyl]-3-phenylurea

CAS 714278-79-2C₂₀H₁₉N₃O₃S

N-[4-(Aminosulfonyl)phenyl]-4-[(anilinocarbonyl)amino]benzenesulfonamide chemical structure, C19H18N4O5S2, CAS 433258-66-3

N-[4-(Aminosulfonyl)phenyl]-4-[(anilinocarbonyl)amino]benzenesulfonamide

CAS 433258-66-3C₁₉H₁₈N₄O₅S₂

1-(4-Acetylphenyl)-3-[4-[(4-methoxyphenyl)sulfamoyl]phenyl]urea chemical structure, C22H21N3O5S, CAS 708238-48-6

1-(4-Acetylphenyl)-3-[4-[(4-methoxyphenyl)sulfamoyl]phenyl]urea

CAS 708238-48-6C₂₂H₂₁N₃O₅S

1-(4-Chlorophenyl)-3-[4-(phenylsulfamoyl)phenyl]urea chemical structure, C19H16ClN3O3S, CAS 651296-00-3

1-(4-Chlorophenyl)-3-[4-(phenylsulfamoyl)phenyl]urea

CAS 651296-00-3C₁₉H₁₆ClN₃O₃S

1-(3-Chlorophenyl)-3-[4-[(2,6-dimethylphenyl)sulfamoyl]phenyl]urea chemical structure, C21H20ClN3O3S, CAS 827013-91-2

1-(3-Chlorophenyl)-3-[4-[(2,6-dimethylphenyl)sulfamoyl]phenyl]urea

CAS 827013-91-2C₂₁H₂₀ClN₃O₃S

1-(4-Chlorophenyl)-3-[4-[(2,3-dichlorophenyl)sulfamoyl]phenyl]urea chemical structure, C19H14Cl3N3O3S, CAS 833431-17-7

1-(4-Chlorophenyl)-3-[4-[(2,3-dichlorophenyl)sulfamoyl]phenyl]urea

CAS 833431-17-7C₁₉H₁₄Cl₃N₃O₃S

1-(4-Chlorophenyl)-3-[4-[(4-sulfamoylphenyl)sulfamoyl]phenyl]urea chemical structure, C19H17ClN4O5S2, CAS 433314-20-6

1-(4-Chlorophenyl)-3-[4-[(4-sulfamoylphenyl)sulfamoyl]phenyl]urea

CAS 433314-20-6C₁₉H₁₇ClN₄O₅S₂

1-[4-[(3,4-Dichlorophenyl)sulfamoyl]phenyl]-3-(4-nitrophenyl)urea chemical structure, C19H14Cl2N4O5S, CAS 706772-75-0

1-[4-[(3,4-Dichlorophenyl)sulfamoyl]phenyl]-3-(4-nitrophenyl)urea

CAS 706772-75-0C₁₉H₁₄Cl₂N₄O₅S

1-(4-Acetylphenyl)-3-[4-[(3,5-dichlorophenyl)sulfamoyl]phenyl]urea chemical structure, C21H17Cl2N3O4S, CAS 824423-93-0

1-(4-Acetylphenyl)-3-[4-[(3,5-dichlorophenyl)sulfamoyl]phenyl]urea

CAS 824423-93-0C₂₁H₁₇Cl₂N₃O₄S

1-(4-Nitrophenyl)-3-[4-[(2,4,6-trimethylphenyl)sulfamoyl]phenyl]urea chemical structure, C22H22N4O5S, CAS 708232-88-6

1-(4-Nitrophenyl)-3-[4-[(2,4,6-trimethylphenyl)sulfamoyl]phenyl]urea

CAS 708232-88-6C₂₂H₂₂N₄O₅S

1-(3-Acetylphenyl)-3-[4-[(2,4,6-trimethylphenyl)sulfamoyl]phenyl]urea chemical structure, C24H25N3O4S, CAS 824941-74-4

1-(3-Acetylphenyl)-3-[4-[(2,4,6-trimethylphenyl)sulfamoyl]phenyl]urea

CAS 824941-74-4C₂₄H₂₅N₃O₄S

1-(4-Chlorophenyl)-3-[4-[(2,5-dimethoxyphenyl)sulfamoyl]phenyl]urea chemical structure, C21H20ClN3O5S, CAS 835888-40-9

1-(4-Chlorophenyl)-3-[4-[(2,5-dimethoxyphenyl)sulfamoyl]phenyl]urea

CAS 835888-40-9C₂₁H₂₀ClN₃O₅S

1-[4-[(5-Chloro-2-methylphenyl)sulfamoyl]phenyl]-3-(4-chlorophenyl)urea
838814-90-7C₂₀H₁₇Cl₂N₃O₃S