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Murcko scaffold

Ring system with 2 rings and 14 atoms

41 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
41
With full pages
5
Scaffold SMILES

O=c1[nH][nH]cc1N=Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH][nH]cc1N=Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 41 of 41 chemicals

4,5-Dioxo-3-methyl-2-pyrazoline-1-carboxamide 4-((o-ethoxyphenyl)hydrazone) chemical structure, C13H15N5O3, CAS 22948-48-7
4,5-Dioxo-3-methyl-2-pyrazoline-1-carboxamide 4-((o-ethoxyphenyl)hydrazone)
CAS 22948-48-7C13H15N5O3
4,5-Dioxo-3-methyl-2-pyrazoline-1-carboxamide 4-(2,5-xylylhydrazone) chemical structure, C13H15N5O2, CAS 22948-54-5
4,5-Dioxo-3-methyl-2-pyrazoline-1-carboxamide 4-(2,5-xylylhydrazone)
CAS 22948-54-5C13H15N5O2
4,5-Dioxo-3-methyl-2-pyrazoline-1-carboxamide 4-(3,5-xylylhydrazone) chemical structure, C13H15N5O2, CAS 34388-24-4
4,5-Dioxo-3-methyl-2-pyrazoline-1-carboxamide 4-(3,5-xylylhydrazone)
CAS 34388-24-4C13H15N5O2
3-Amino-5-hydroxy-4-phenylazopyrazole chemical structure, C9H9N5O, CAS 6627-93-6
3-Amino-5-hydroxy-4-phenylazopyrazole
CAS 6627-93-6C9H9N5O
4-Phenylhydrazono-3-methyl-2-pyrazolin-5-one chemical structure, C10H10N4O, CAS 13572-24-2
4-Phenylhydrazono-3-methyl-2-pyrazolin-5-one
CAS 13572-24-2C10H10N4O
(4Z)-2,5-Dimethyl-4-(phenylhydrazinylidene)pyrazol-3-one chemical structure, C11H12N4O, CAS 13572-25-3
(4Z)-2,5-Dimethyl-4-(phenylhydrazinylidene)pyrazol-3-one
CAS 13572-25-3C11H12N4O
4-[(4-Methoxyphenyl)diazenyl]-2,5-dimethyl-1H-pyrazol-3-one chemical structure, C12H14N4O2, CAS 65078-41-3
4-[(4-Methoxyphenyl)diazenyl]-2,5-dimethyl-1H-pyrazol-3-one
CAS 65078-41-3C12H14N4O2
(4E)-3-Methyl-4-[2-(4-methylphenyl)hydrazinylidene]-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothioamide chemical structure, C12H13N5OS, CAS 26178-94-9
(4E)-3-Methyl-4-[2-(4-methylphenyl)hydrazinylidene]-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothioamide
CAS 26178-94-9C12H13N5OS
(4Z)-4-[2-(2,5-Dichlorophenyl)hydrazinylidene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothioamide chemical structure, C11H9Cl2N5OS, CAS 26179-06-6
(4Z)-4-[2-(2,5-Dichlorophenyl)hydrazinylidene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothioamide
CAS 26179-06-6C11H9Cl2N5OS
(4Z)-4-[2-(2,5-Dimethoxyphenyl)hydrazinylidene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothioamide chemical structure, C13H15N5O3S, CAS 26179-08-8
(4Z)-4-[2-(2,5-Dimethoxyphenyl)hydrazinylidene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothioamide
CAS 26179-08-8C13H15N5O3S
(4Z)-4-[2-(2,5-Dimethylphenyl)hydrazinylidene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothioamide chemical structure, C13H15N5OS, CAS 26178-97-2
(4Z)-4-[2-(2,5-Dimethylphenyl)hydrazinylidene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothioamide
CAS 26178-97-2C13H15N5OS
4-[2-(3-Methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazino]benzenesulfonamide chemical structure, C10H11N5O3S, CAS 57857-01-9
4-[2-(3-Methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazino]benzenesulfonamide
CAS 57857-01-9C10H11N5O3S
3-Methyl-1H-pyrazole-4,5-dione 4-{N-[3-(trifluoromethyl)phenyl]hydrazone} chemical structure, C11H9F3N4O, CAS 121831-74-1
3-Methyl-1H-pyrazole-4,5-dione 4-{N-[3-(trifluoromethyl)phenyl]hydrazone}
CAS 121831-74-1C11H9F3N4O
1H-Pyrazole-4,5-dione 4-[N-(4-chlorophenyl)hydrazone] chemical structure, C9H7ClN4O, CAS 338416-61-8
1H-Pyrazole-4,5-dione 4-[N-(4-chlorophenyl)hydrazone]
CAS 338416-61-8C9H7ClN4O
1H-Pyrazole-4,5-dione 4-[N-(3-chlorophenyl)hydrazone] chemical structure, C9H7ClN4O, CAS 338416-83-4
1H-Pyrazole-4,5-dione 4-[N-(3-chlorophenyl)hydrazone]
CAS 338416-83-4C9H7ClN4O
1H-Pyrazole-4,5-dione 4-[N-(2-chlorophenyl)hydrazone] chemical structure, C9H7ClN4O, CAS 338416-85-6
1H-Pyrazole-4,5-dione 4-[N-(2-chlorophenyl)hydrazone]
CAS 338416-85-6C9H7ClN4O
1H-Pyrazole-4,5-dione 4-{N-[2-(trifluoromethyl)phenyl]hydrazone} chemical structure, C10H7F3N4O, CAS 338416-87-8
1H-Pyrazole-4,5-dione 4-{N-[2-(trifluoromethyl)phenyl]hydrazone}
CAS 338416-87-8C10H7F3N4O
1H-Pyrazole-4,5-dione 4-[N-(3-methoxyphenyl)hydrazone] chemical structure, C10H10N4O2, CAS 338416-89-0
1H-Pyrazole-4,5-dione 4-[N-(3-methoxyphenyl)hydrazone]
CAS 338416-89-0C10H10N4O2
(4Z)-4-[(2-Methoxy-5-nitrophenyl)hydrazinylidene]-3-methyl-5-oxopyrazole-1-carbothioamide chemical structure, C12H12N6O4S, CAS 327041-82-7
(4Z)-4-[(2-Methoxy-5-nitrophenyl)hydrazinylidene]-3-methyl-5-oxopyrazole-1-carbothioamide
CAS 327041-82-7C12H12N6O4S
(4Z)-3-Methyl-4-[2-(2-nitrophenyl)hydrazinylidene]-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothioamide chemical structure, C11H10N6O3S, CAS 26178-99-4
(4Z)-3-Methyl-4-[2-(2-nitrophenyl)hydrazinylidene]-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothioamide
CAS 26178-99-4C11H10N6O3S
4,5-Dihydro-3-(trifluoromethyl)pyrazole-4,5-dione 4-[3-(trifluoromethyl)phenyl]hydrazone chemical structure, C11H6F6N4O, CAS 30613-53-7
4,5-Dihydro-3-(trifluoromethyl)pyrazole-4,5-dione 4-[3-(trifluoromethyl)phenyl]hydrazone
CAS 30613-53-7C11H6F6N4O
4-[(2,6-Dimethylphenyl)diazenyl]-5-methyl-3-oxo-1H-pyrazole-2-carbothioamide chemical structure, C13H15N5OS, CAS 26178-98-3
4-[(2,6-Dimethylphenyl)diazenyl]-5-methyl-3-oxo-1H-pyrazole-2-carbothioamide
CAS 26178-98-3C13H15N5OS
3-Methyl-4-(4-nitrophenyl)azo-5-oxo-4H-pyrazole-1-carbothioamide chemical structure, C11H10N6O3S, CAS 26179-01-1
3-Methyl-4-(4-nitrophenyl)azo-5-oxo-4H-pyrazole-1-carbothioamide
CAS 26179-01-1C11H10N6O3S
4-[(E)-2-(4-Chlorophenyl)diazenyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-ol chemical structure, C11H8ClF3N4O, CAS 318959-09-0
4-[(E)-2-(4-Chlorophenyl)diazenyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-ol
CAS 318959-09-0C11H8ClF3N4O