CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 10 atoms

5 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
5
With full pages
3
Scaffold SMILES

O=C1C[NH+]2CC(=O)O[BH-]2O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C[NH+]2CC(=O)O[BH-]2O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

trans-2-Bromovinylboronic acid MIDA ester chemical structure, C7H9BBrNO4, CAS 1005452-52-7
trans-2-Bromovinylboronic acid MIDA ester
CAS 1005452-52-7C7H9BBrNO4
4-Methyl-8-(4-methyl-1-oxopentan-2-yl)-2,6-dioxohexahydro-[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide chemical structure, C11H18BNO5, CAS 1380504-24-4
4-Methyl-8-(4-methyl-1-oxopentan-2-yl)-2,6-dioxohexahydro-[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide
CAS 1380504-24-4C11H18BNO5
1-Bromovinyl-1-boronic acid mida ester chemical structure, C7H9BBrNO4, CAS 1449377-16-5
1-Bromovinyl-1-boronic acid mida ester
CAS 1449377-16-5C7H9BBrNO4
(E)-8-(2-Bromovinyl)-4-methyl-2,6-dioxohexahydro-[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide chemical structure, C7H9BBrNO4, CAS 1105069-27-9
(E)-8-(2-Bromovinyl)-4-methyl-2,6-dioxohexahydro-[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide
CAS 1105069-27-9C7H9BBrNO4
1-[3-[tert-Butyl(dimethyl)silyl]oxyprop-1-ynyl]-5-methyl-2,8-dioxa-5-azonia-1-boranuidabicyclo[3.3.0]octane-3,7-dione chemical structure, C14H24BNO5Si, CAS 1373340-75-0
1-[3-[tert-Butyl(dimethyl)silyl]oxyprop-1-ynyl]-5-methyl-2,8-dioxa-5-azonia-1-boranuidabicyclo[3.3.0]octane-3,7-dione
CAS 1373340-75-0C14H24BNO5Si