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Murcko scaffold

Ring system with 3 rings and 16 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
8
With full pages
5
Scaffold SMILES

O=C(Nc1cc2c(s1)CCC2)c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cc2c(s1)CCC2)c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-(2-Furoylamino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid chemical structure, C13H11NO4S, CAS 315709-88-7
2-(2-Furoylamino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid
CAS 315709-88-7C13H11NO4S
2-[[2-Furanyl(oxo)methyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid methyl ester chemical structure, C14H13NO4S, CAS 302803-01-6
2-[[2-Furanyl(oxo)methyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid methyl ester
CAS 302803-01-6C14H13NO4S
Ethyl 2-(2-furylcarbonylamino)-4,5,6-trihydrocyclopenta[2,1-b]thiophene-3-carb oxylate chemical structure, C15H15NO4S, CAS 300828-80-2
Ethyl 2-(2-furylcarbonylamino)-4,5,6-trihydrocyclopenta[2,1-b]thiophene-3-carb oxylate
CAS 300828-80-2C15H15NO4S
N-(3-Cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-5-nitrofuran-2-carboxamide chemical structure, C13H9N3O4S, CAS 461427-13-4
N-(3-Cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-5-nitrofuran-2-carboxamide
CAS 461427-13-4C13H9N3O4S
Dimethyl 2-(furan-2-carbonylamino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3,4-dicarboxylate chemical structure, C16H15NO6S, CAS 302577-38-4
Dimethyl 2-(furan-2-carbonylamino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3,4-dicarboxylate
CAS 302577-38-4C16H15NO6S
Methyl 2-(5-nitrofuran-2-carboxamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate chemical structure, C14H12N2O6S, CAS 477579-02-5
Methyl 2-(5-nitrofuran-2-carboxamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
CAS 477579-02-5C14H12N2O6S
N-[3-(Methylcarbamoyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide chemical structure, C14H14N2O3S, CAS 893094-77-4
N-[3-(Methylcarbamoyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide
CAS 893094-77-4C14H14N2O3S
N-(3-(Methylcarbamoyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-5-nitrofuran-2-carboxamide chemical structure, C14H13N3O5S, CAS 893095-06-2
N-(3-(Methylcarbamoyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-5-nitrofuran-2-carboxamide
CAS 893095-06-2C14H13N3O5S