CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 15 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
13
With full pages
3
Scaffold SMILES

c1ccc(-c2ccnc3c2CCC3)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccnc3c2CCC3)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

2-Amino-4-(4-methoxyphenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile chemical structure, C16H15N3O, CAS 74873-45-3
2-Amino-4-(4-methoxyphenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile
CAS 74873-45-3C16H15N3O
2-Amino-4-(4-fluorophenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile chemical structure, C15H12FN3, CAS 327098-36-2
2-Amino-4-(4-fluorophenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile
CAS 327098-36-2C15H12FN3
2-Amino-4-(2-chlorophenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile chemical structure, C15H12ClN3, CAS 163978-34-5
2-Amino-4-(2-chlorophenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile
CAS 163978-34-5C15H12ClN3
2-(2-Oxopropylsulfanyl)-4-phenyl-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile chemical structure, C18H16N2OS, CAS 445384-97-4
2-(2-Oxopropylsulfanyl)-4-phenyl-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile
CAS 445384-97-4C18H16N2OS
4-(4-Hydroxyphenyl)-2-(methylthio)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile chemical structure, C16H14N2OS, CAS 694463-05-3
4-(4-Hydroxyphenyl)-2-(methylthio)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile
CAS 694463-05-3C16H14N2OS
4-(4-Chlorophenyl)-2-(3,3-dimethyl-2-oxobutyl)sulfanyl-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile chemical structure, C21H21ClN2OS, CAS 340813-57-2
4-(4-Chlorophenyl)-2-(3,3-dimethyl-2-oxobutyl)sulfanyl-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile
CAS 340813-57-2C21H21ClN2OS
2-Chloro-4-(2,4-difluoro-phenyl)-6,7-dihydro-5H-[1]pyrindine chemical structure, C14H10ClF2N, CAS 132813-01-5
2-Chloro-4-(2,4-difluoro-phenyl)-6,7-dihydro-5H-[1]pyrindine
CAS 132813-01-5C14H10ClF2N
4-(2-Chloro-3,4-dimethoxyphenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine chemical structure, C16H16ClNO2, CAS 1225209-70-0
4-(2-Chloro-3,4-dimethoxyphenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine
CAS 1225209-70-0C16H16ClNO2
tert-Butyl-[2-[tert-butyl(dimethyl)silyl]oxy-3-chloro-4-(6,7-dihydro-5H-cyclopenta[b]pyridin-4-yl)phenoxy]-dimethylsilane chemical structure, C26H40ClNO2Si2, CAS 1225209-72-2
tert-Butyl-[2-[tert-butyl(dimethyl)silyl]oxy-3-chloro-4-(6,7-dihydro-5H-cyclopenta[b]pyridin-4-yl)phenoxy]-dimethylsilane
CAS 1225209-72-2C26H40ClNO2Si2
2-Chloro-4-(4-fluorophenyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol chemical structure, C14H11ClFNO, CAS 143214-13-5
2-Chloro-4-(4-fluorophenyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol
CAS 143214-13-5C14H11ClFNO
Ethyl 2-({3-cyano-4-[4-(propan-2-yl)phenyl]-5H,6H,7H-cyclopenta[b]pyridin-2-yl}sulfanyl)acetate chemical structure, C22H24N2O2S, CAS 1001648-54-9
Ethyl 2-({3-cyano-4-[4-(propan-2-yl)phenyl]-5H,6H,7H-cyclopenta[b]pyridin-2-yl}sulfanyl)acetate
CAS 1001648-54-9C22H24N2O2S
2-Chloro-4-(3,4-dichlorophenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile chemical structure, C15H9Cl3N2, CAS 1779124-69-4
2-Chloro-4-(3,4-dichlorophenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile
CAS 1779124-69-4C15H9Cl3N2
2-Chloro-4-(3-fluorophenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile chemical structure, C15H10ClFN2, CAS 1708079-56-4
2-Chloro-4-(3-fluorophenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile
CAS 1708079-56-4C15H10ClFN2