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Murcko scaffold

4-(Piperidin-4-yl)pyrimidine scaffold

153 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
153
With full pages
5
Scaffold SMILES

c1cc(C2CCNCC2)ncn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Piperidin-4-yl)pyrimidine page
Murcko scaffold c1cc(C2CCNCC2)ncn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 153 chemicals

4-(Piperidin-4-yl)pyrimidine chemical structure, C9H13N3, CAS 954220-47-4
4-(Piperidin-4-yl)pyrimidine
CAS 954220-47-4C9H13N3
4-(6-Chloro-4-pyrimidinyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester chemical structure, C14H20ClN3O2, CAS 954232-45-2
4-(6-Chloro-4-pyrimidinyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
CAS 954232-45-2C14H20ClN3O2
5-Bromo-4-(4-piperidyl)pyrimidine chemical structure, C9H12BrN3, CAS 954220-41-8
5-Bromo-4-(4-piperidyl)pyrimidine
CAS 954220-41-8C9H12BrN3
5-Fluoro-4-(piperidin-4-yl)pyrimidine chemical structure, C9H12FN3, CAS 954220-44-1
5-Fluoro-4-(piperidin-4-yl)pyrimidine
CAS 954220-44-1C9H12FN3
2-Methyl-4-(piperidin-4-yl)pyrimidine chemical structure, C10H15N3, CAS 949100-33-8
2-Methyl-4-(piperidin-4-yl)pyrimidine
CAS 949100-33-8C10H15N3
4-Piperidin-4-yl-pyrimidine dihydrochloride chemical structure, C9H15Cl2N3, CAS 1185304-08-8
4-Piperidin-4-yl-pyrimidine dihydrochloride
CAS 1185304-08-8C9H15Cl2N3
tert-Butyl 4-(2-chloropyrimidin-4-yl)piperidine-1-carboxylate chemical structure, C14H20ClN3O2, CAS 1001754-82-0
tert-Butyl 4-(2-chloropyrimidin-4-yl)piperidine-1-carboxylate
CAS 1001754-82-0C14H20ClN3O2
tert-Butyl 4-(2-chloro-6-methylpyrimidin-4-yl)piperidine-1-carboxylate chemical structure, C15H22ClN3O2, CAS 1312760-62-5
tert-Butyl 4-(2-chloro-6-methylpyrimidin-4-yl)piperidine-1-carboxylate
CAS 1312760-62-5C15H22ClN3O2
tert-Butyl 4-(2-Chloro-5-fluoropyrimidin-4-yl)piperidine-1-carboxylate chemical structure, C14H19ClFN3O2, CAS 1053657-03-6
tert-Butyl 4-(2-Chloro-5-fluoropyrimidin-4-yl)piperidine-1-carboxylate
CAS 1053657-03-6C14H19ClFN3O2
4-(Piperidin-4-yl)pyrimidine hydrochloride chemical structure, C9H14ClN3, CAS 1955505-79-9
4-(Piperidin-4-yl)pyrimidine hydrochloride
CAS 1955505-79-9C9H14ClN3
tert-Butyl 4-[5-bromo-2-(tert-butyl)-4-pyrimidinyl]-1-piperidinecarboxylate chemical structure, C18H28BrN3O2, CAS 1221278-47-2
tert-Butyl 4-[5-bromo-2-(tert-butyl)-4-pyrimidinyl]-1-piperidinecarboxylate
CAS 1221278-47-2C18H28BrN3O2
2-Chloro-4-(piperidin-4-yl)pyrimidine chemical structure, C9H12ClN3, CAS 1001754-79-5
2-Chloro-4-(piperidin-4-yl)pyrimidine
CAS 1001754-79-5C9H12ClN3
4-(Piperidin-4-yl)-2-(trifluoromethyl)pyrimidine chemical structure, C10H12F3N3, CAS 914299-53-9
4-(Piperidin-4-yl)-2-(trifluoromethyl)pyrimidine
CAS 914299-53-9C10H12F3N3
4-Chloro-6-(piperidin-4-yl)pyrimidine chemical structure, C9H12ClN3, CAS 749207-93-0
4-Chloro-6-(piperidin-4-yl)pyrimidine
CAS 749207-93-0C9H12ClN3
4-(Piperidin-4-yl)-2-(propan-2-yl)pyrimidine chemical structure, C12H19N3, CAS 1247142-15-9
4-(Piperidin-4-yl)-2-(propan-2-yl)pyrimidine
CAS 1247142-15-9C12H19N3
Piperidin-4-yl-aminopyrimidine chemical structure, C9H14N4, CAS 1211532-88-5
Piperidin-4-yl-aminopyrimidine
CAS 1211532-88-5C9H14N4
4-(6-Chloro-2-methylpyrimidin-4-yl)-N,N-dimethylpiperidine-1-sulfonamide chemical structure, C12H19ClN4O2S, CAS 1361111-89-8
4-(6-Chloro-2-methylpyrimidin-4-yl)-N,N-dimethylpiperidine-1-sulfonamide
CAS 1361111-89-8C12H19ClN4O2S
tert-Butyl 4-(6-chloro-2-methylpyrimidin-4-yl)piperidine-1-carboxylate chemical structure, C15H22ClN3O2, CAS 1361118-66-2
tert-Butyl 4-(6-chloro-2-methylpyrimidin-4-yl)piperidine-1-carboxylate
CAS 1361118-66-2C15H22ClN3O2
5-Iodo-N,N-dimethyl-4-(1-methylpiperidin-4-yl)pyrimidin-2-amine chemical structure, C12H19IN4, CAS 1361115-00-5
5-Iodo-N,N-dimethyl-4-(1-methylpiperidin-4-yl)pyrimidin-2-amine
CAS 1361115-00-5C12H19IN4
5-Iodo-4-(1-isopropylpiperidin-4-yl)-N,N-dimethylpyrimidin-2-amine chemical structure, C14H23IN4, CAS 1361115-12-9
5-Iodo-4-(1-isopropylpiperidin-4-yl)-N,N-dimethylpyrimidin-2-amine
CAS 1361115-12-9C14H23IN4
1-(4-(2-(Dimethylamino)-5-iodopyrimidin-4-yl)piperidin-1-yl)ethanone chemical structure, C13H19IN4O, CAS 1361113-50-9
1-(4-(2-(Dimethylamino)-5-iodopyrimidin-4-yl)piperidin-1-yl)ethanone
CAS 1361113-50-9C13H19IN4O
5-Iodo-N,N-dimethyl-4-(1-(methylsulfonyl)piperidin-4-yl)pyrimidin-2-amine chemical structure, C12H19IN4O2S, CAS 1361111-99-0
5-Iodo-N,N-dimethyl-4-(1-(methylsulfonyl)piperidin-4-yl)pyrimidin-2-amine
CAS 1361111-99-0C12H19IN4O2S
N,N-Dimethyl-4-(piperidin-4-yl)pyrimidin-2-amine chemical structure, C11H18N4, CAS 1141374-07-3
N,N-Dimethyl-4-(piperidin-4-yl)pyrimidin-2-amine
CAS 1141374-07-3C11H18N4
2-(2-Amino-6-piperidin-4-ylpyrimidin-4-yl)ethanol hydrochloride chemical structure, C11H18N4O, CAS 1824261-51-9
2-(2-Amino-6-piperidin-4-ylpyrimidin-4-yl)ethanol hydrochloride
CAS 1824261-51-9C11H18N4O