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Murcko scaffold

1-Piperidineacetamide, N-2-thiazolyl- scaffold

27 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
27
With full pages
5
Scaffold SMILES

O=C(CN1CCCCC1)Nc1nccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Piperidineacetamide, N-2-thiazolyl- page
Murcko scaffold O=C(CN1CCCCC1)Nc1nccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

1-Piperidineacetamide, N-(5-chloro-2-thiazolyl)-, monohydrochloride chemical structure, C10H15Cl2N3OS, CAS 35041-91-9
1-Piperidineacetamide, N-(5-chloro-2-thiazolyl)-, monohydrochloride
CAS 35041-91-9C10H15Cl2N3OS
Ethyl 2-[(2-piperidinoacetyl)amino]-1,3-thiazole-4-carboxylate chemical structure, C13H19N3O3S, CAS 223790-92-9
Ethyl 2-[(2-piperidinoacetyl)amino]-1,3-thiazole-4-carboxylate
CAS 223790-92-9C13H19N3O3S
1-Piperidineacetamide, N-2-thiazolyl- chemical structure, C10H15N3OS, CAS 66157-54-8
1-Piperidineacetamide, N-2-thiazolyl-
CAS 66157-54-8C10H15N3OS
2-(4-Methylpiperidin-1-yl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C11H17N3OS, CAS 831250-25-0
2-(4-Methylpiperidin-1-yl)-N-(1,3-thiazol-2-yl)acetamide
CAS 831250-25-0C11H17N3OS
1-[2-Oxo-2-(1,3-thiazol-2-ylamino)ethyl]piperidine-4-carboxamide chemical structure, C11H16N4O2S, CAS 878442-70-7
1-[2-Oxo-2-(1,3-thiazol-2-ylamino)ethyl]piperidine-4-carboxamide
CAS 878442-70-7C11H16N4O2S
1-(Thiazol-2-ylcarbamoylmethyl)-piperidine-3-carboxylic acid ethyl ester chemical structure, C13H19N3O3S, CAS 880073-75-6
1-(Thiazol-2-ylcarbamoylmethyl)-piperidine-3-carboxylic acid ethyl ester
CAS 880073-75-6C13H19N3O3S
2-[[2-(1-Piperidinyl)acetyl]amino]-4-carbethoxymethylthiazol e chemical structure, C14H21N3O3S, CAS 223755-42-8
2-[[2-(1-Piperidinyl)acetyl]amino]-4-carbethoxymethylthiazol e
CAS 223755-42-8C14H21N3O3S
2-(Piperidin-1-yl)-N-(1,3-thiazol-2-yl)propanamide chemical structure, C11H17N3OS, CAS 916031-08-8
2-(Piperidin-1-yl)-N-(1,3-thiazol-2-yl)propanamide
CAS 916031-08-8C11H17N3OS
N-(4,5-Dimethyl-1,3-thiazol-2-yl)-2-(4-methylpiperidin-1-yl)acetamide chemical structure, C13H21N3OS, CAS 916036-86-7
N-(4,5-Dimethyl-1,3-thiazol-2-yl)-2-(4-methylpiperidin-1-yl)acetamide
CAS 916036-86-7C13H21N3OS
2-(4-Methylpiperidin-1-yl)-N-(1,3-thiazol-2-yl)propanamide chemical structure, C12H19N3OS, CAS 924975-38-2
2-(4-Methylpiperidin-1-yl)-N-(1,3-thiazol-2-yl)propanamide
CAS 924975-38-2C12H19N3OS
1-[1-Oxo-1-(1,3-thiazol-2-ylamino)propan-2-yl]piperidine-4-carboxamide chemical structure, C12H18N4O2S, CAS 936819-64-6
1-[1-Oxo-1-(1,3-thiazol-2-ylamino)propan-2-yl]piperidine-4-carboxamide
CAS 936819-64-6C12H18N4O2S
2-(4-Aminopiperidin-1-yl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C10H16N4OS, CAS 1082545-32-1
2-(4-Aminopiperidin-1-yl)-N-(1,3-thiazol-2-yl)acetamide
CAS 1082545-32-1C10H16N4OS
2-(4-Hydroxypiperidin-1-yl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C10H15N3O2S, CAS 679395-10-9
2-(4-Hydroxypiperidin-1-yl)-N-(1,3-thiazol-2-yl)acetamide
CAS 679395-10-9C10H15N3O2S
2-(4-Hydroxypiperidin-1-yl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C11H17N3O2S, CAS 679395-11-0
2-(4-Hydroxypiperidin-1-yl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide
CAS 679395-11-0C11H17N3O2S
2-(4-Methylpiperidin-1-yl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C12H19N3OS, CAS 946953-63-5
2-(4-Methylpiperidin-1-yl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide
CAS 946953-63-5C12H19N3OS
2-(4-Aminopiperidin-1-yl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C11H18N4OS, CAS 1154550-03-4
2-(4-Aminopiperidin-1-yl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide
CAS 1154550-03-4C11H18N4OS
2-(3-Hydroxypiperidin-1-yl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C11H17N3O2S, CAS 1455353-87-3
2-(3-Hydroxypiperidin-1-yl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide
CAS 1455353-87-3C11H17N3O2S
2-[3-(Hydroxymethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)acetamide chemical structure, C11H17N3O2S, CAS 1461630-90-9
2-[3-(Hydroxymethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)acetamide
CAS 1461630-90-9C11H17N3O2S
2-(3-Hydroxypiperidin-1-yl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C10H15N3O2S, CAS 1247610-79-2
2-(3-Hydroxypiperidin-1-yl)-N-(1,3-thiazol-2-yl)acetamide
CAS 1247610-79-2C10H15N3O2S
2-[4-(Hydroxymethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)acetamide chemical structure, C11H17N3O2S, CAS 1460289-94-4
2-[4-(Hydroxymethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)acetamide
CAS 1460289-94-4C11H17N3O2S
2-(3-Aminopiperidin-1-yl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C10H16N4OS, CAS 1248360-18-0
2-(3-Aminopiperidin-1-yl)-N-(1,3-thiazol-2-yl)acetamide
CAS 1248360-18-0C10H16N4OS
2-(3-Aminopiperidin-1-yl)-N-(4-methylthiazol-2-yl)acetamide chemical structure, C11H18N4OS, CAS 1306229-32-2
2-(3-Aminopiperidin-1-yl)-N-(4-methylthiazol-2-yl)acetamide
CAS 1306229-32-2C11H18N4OS
2-[4-(Aminomethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)acetamide chemical structure, C11H18N4OS, CAS 1285251-17-3
2-[4-(Aminomethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)acetamide
CAS 1285251-17-3C11H18N4OS
2-[3-(Aminomethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)acetamide chemical structure, C11H18N4OS, CAS 1283346-32-6
2-[3-(Aminomethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)acetamide
CAS 1283346-32-6C11H18N4OS