Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 4 rings and 24 atoms

48 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 24
Chemicals: 48
With full pages: 1

Scaffold SMILES

O=C1C(=Cc2ccccc2)Oc2c(CN3CCOCC3)cccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1C(=Cc2ccccc2)Oc2c(CN3CCOCC3)cccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

(Z)-2-(2,3-Dimethoxybenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C22H23NO6, CAS 859135-13-0

(Z)-2-(2,3-Dimethoxybenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 859135-13-0C₂₂H₂₃NO₆

(Z)-6-Hydroxy-7-(morpholinomethyl)-2-(2,3,4-trimethoxybenzylidene)benzofuran-3(2H)-one chemical structure, C23H25NO7, CAS 859663-78-8

(Z)-6-Hydroxy-7-(morpholinomethyl)-2-(2,3,4-trimethoxybenzylidene)benzofuran-3(2H)-one

CAS 859663-78-8C₂₃H₂₅NO₇

(Z)-6-Hydroxy-7-(morpholinomethyl)-2-(2,4,5-trimethoxybenzylidene)benzofuran-3(2H)-one chemical structure, C23H25NO7, CAS 859666-92-5

(Z)-6-Hydroxy-7-(morpholinomethyl)-2-(2,4,5-trimethoxybenzylidene)benzofuran-3(2H)-one

CAS 859666-92-5C₂₃H₂₅NO₇

(Z)-6-Hydroxy-2-(3-methylbenzylidene)-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C21H21NO4, CAS 896805-59-7

(Z)-6-Hydroxy-2-(3-methylbenzylidene)-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 896805-59-7C₂₁H₂₁NO₄

(Z)-2-(2-Chloro-6-fluorobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C20H17ClFNO4, CAS 896825-71-1

(Z)-2-(2-Chloro-6-fluorobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 896825-71-1C₂₀H₁₇ClFNO₄

(Z)-6-Hydroxy-2-(2-methylbenzylidene)-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C21H21NO4, CAS 896828-82-3

(Z)-6-Hydroxy-2-(2-methylbenzylidene)-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 896828-82-3C₂₁H₂₁NO₄

(Z)-2-(4-Bromobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C20H18BrNO4, CAS 896827-61-5

(Z)-2-(4-Bromobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 896827-61-5C₂₀H₁₈BrNO₄

(Z)-6-Hydroxy-7-(morpholinomethyl)-2-(4-nitrobenzylidene)benzofuran-3(2H)-one chemical structure, C20H18N2O6, CAS 896840-51-0

(Z)-6-Hydroxy-7-(morpholinomethyl)-2-(4-nitrobenzylidene)benzofuran-3(2H)-one

CAS 896840-51-0C₂₀H₁₈N₂O₆

(Z)-2-(4-Ethylbenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C22H23NO4, CAS 896840-90-7

(Z)-2-(4-Ethylbenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 896840-90-7C₂₂H₂₃NO₄

(Z)-6-Hydroxy-7-(morpholinomethyl)-2-(3-nitrobenzylidene)benzofuran-3(2H)-one chemical structure, C20H18N2O6, CAS 899396-67-9

(Z)-6-Hydroxy-7-(morpholinomethyl)-2-(3-nitrobenzylidene)benzofuran-3(2H)-one

CAS 899396-67-9C₂₀H₁₈N₂O₆

(Z)-2-(3-Chlorobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C20H18ClNO4, CAS 899391-81-2

(Z)-2-(3-Chlorobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 899391-81-2C₂₀H₁₈ClNO₄

(Z)-2-(2-Bromobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C20H18BrNO4, CAS 899405-21-1

(Z)-2-(2-Bromobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 899405-21-1C₂₀H₁₈BrNO₄

(Z)-2-(3-Fluorobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C20H18FNO4, CAS 899389-49-2

(Z)-2-(3-Fluorobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 899389-49-2C₂₀H₁₈FNO₄

(Z)-2-(3,4-Dichlorobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C20H17Cl2NO4, CAS 900272-44-8

(Z)-2-(3,4-Dichlorobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 900272-44-8C₂₀H₁₇Cl₂NO₄

(Z)-2-(2,6-Dichlorobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C20H17Cl2NO4, CAS 896066-00-5

(Z)-2-(2,6-Dichlorobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 896066-00-5C₂₀H₁₇Cl₂NO₄

(Z)-2-(3-Bromobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C20H18BrNO4, CAS 899399-13-4

(Z)-2-(3-Bromobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 899399-13-4C₂₀H₁₈BrNO₄

(Z)-2-(5-Bromo-2-methoxybenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C21H20BrNO5, CAS 899389-81-2

(Z)-2-(5-Bromo-2-methoxybenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 899389-81-2C₂₁H₂₀BrNO₅

(2Z)-6-Hydroxy-2-[(4-methylphenyl)methylidene]-7-(morpholin-4-ylmethyl)-1-benzofuran-3-one chemical structure, C21H21NO4, CAS 869078-08-0

(2Z)-6-Hydroxy-2-[(4-methylphenyl)methylidene]-7-(morpholin-4-ylmethyl)-1-benzofuran-3-one

CAS 869078-08-0C₂₁H₂₁NO₄

(2Z)-2-[(4-Fluorophenyl)methylidene]-6-hydroxy-7-(morpholin-4-ylmethyl)-1-benzofuran-3-one chemical structure, C20H18FNO4, CAS 869078-09-1

(2Z)-2-[(4-Fluorophenyl)methylidene]-6-hydroxy-7-(morpholin-4-ylmethyl)-1-benzofuran-3-one

CAS 869078-09-1C₂₀H₁₈FNO₄

(Z)-2-(4-Chlorobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C20H18ClNO4, CAS 869078-10-4

(Z)-2-(4-Chlorobenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 869078-10-4C₂₀H₁₈ClNO₄

(2Z)-2-[(2-Fluorophenyl)methylidene]-6-hydroxy-7-(morpholin-4-ylmethyl)-1-benzofuran-3-one chemical structure, C20H18FNO4, CAS 869078-12-6

(2Z)-2-[(2-Fluorophenyl)methylidene]-6-hydroxy-7-(morpholin-4-ylmethyl)-1-benzofuran-3-one

CAS 869078-12-6C₂₀H₁₈FNO₄

(Z)-6-Hydroxy-2-(2-methoxybenzylidene)-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C21H21NO5, CAS 869078-13-7

(Z)-6-Hydroxy-2-(2-methoxybenzylidene)-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 869078-13-7C₂₁H₂₁NO₅

(Z)-2-(3,4-Dimethoxybenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C22H23NO6, CAS 869078-14-8

(Z)-2-(3,4-Dimethoxybenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 869078-14-8C₂₂H₂₃NO₆

(Z)-2-(2,4-Dimethoxybenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one chemical structure, C22H23NO6, CAS 869078-16-0

(Z)-2-(2,4-Dimethoxybenzylidene)-6-hydroxy-7-(morpholinomethyl)benzofuran-3(2H)-one

CAS 869078-16-0C₂₂H₂₃NO₆