Murcko scaffold
Dihydrouracil scaffold
221 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 8
- Chemicals
- 221
- With full pages
- 37
Scaffold SMILES
O=C1CCNC(=O)N1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 221 chemicals
(±)-Dihydroorotic acid
CAS 155-54-4C5H6N2O4
Dihydrouracil
CAS 504-07-4C4H6N2O2
5-Iodo-5,6-dihydrouracil
CAS 60763-80-6C4H5IN2O2
2,4(1H,3H)-Pyrimidinedione, 5-fluorodihydro-6-hydroxy-
CAS 37103-91-6C4H5FN2O3
5,6-Dihydro-5-(trifluoromethyl)uracil
CAS 2145-56-4C5H5F3N2O2
Thymine glycol
CAS 2943-56-8C5H8N2O4
Acetic acid, chloro-, hexahydro-2,6-dioxo-5-methyl-5-nitro-4-pyrimidinyl ester
CAS 82531-54-2C7H8ClN3O6
2,6-Dihydroxy-5-methyl-5-nitro-4,5-dihydropyrimidin-4-yl dichloroacetate
CAS 82531-55-3C7H7Cl2N3O6
Dihydro-1-nitroso-2,4(1H,3H)-pyrimidinedione
CAS 16813-36-8C4H5N3O3
Dihydrothymine
CAS 696-04-8C5H8N2O2
Dihydro-6-methyl-2,4(1H,3H)-pyrimidinedione
CAS 2434-49-3C5H8N2O2
5-Bromo-5,6-dihydrouracil
CAS 1193-76-6C4H5BrN2O2
5-Bromo-5-methyldihydropyrimidine-2,4(1H,3H)-dione
CAS 1681-77-2C5H7BrN2O2
5,6-Dihydro-5-fluorouracil
CAS 696-06-0C4H5FN2O2
5-Fluorodihydroorotate
CAS 53305-80-9C5H5FN2O4
Thymine bromohydrin
CAS 57908-04-0C5H7BrN2O3
1-Nitroso-5,6-dihydrothymine
CAS 62641-67-2C5H7N3O3
cis-5,6-Dihydro-6-hydroperoxy-5-hydroxythymine
CAS 33599-50-7C5H8N2O5
Dihydroorotic acid hydrazide
CAS 68453-79-2C5H8N4O3
2,4(1H,3H)-Pyrimidinedione, dihydro-5,6-dihydroxy-5-methyl-, trans-
CAS 1431-06-7C5H8N2O4
2,4(1H,3H)-Pyrimidinedione, dihydro-5,6-dihydroxy-5-methyl-, (5R-trans)-
CAS 57968-50-0C5H8N2O4
cis-5,6-Dihydroxythymine
CAS 1124-84-1C5H8N2O4
2,4(1H,3H)-Pyrimidnedione, dihydro-5,6-dihydroxy-5-methyl-, (5S-cis)-
CAS 57968-49-7C5H8N2O4
6-Hydroxy-5,6-dihydrothymine
CAS 13514-92-6C5H8N2O3
- 2,4(1H,3H)-Pyrimidinedione, 5-fluorodihydro-1,3-dimethyl-83472-56-4C6H9FN2O2
- Tac 27865906-75-4C11H17FN2O5
- Hydroxynitrodihydrothymine59698-25-8C5H7N3O5
- 2,4(1H,3H)-Pyrimidinedione, 5,6-dihydro-1-hydroxy-30204-58-1C4H6N2O3
- 3-Hydroxydihydropyrimidine-2,4(1H,3H)-dione5461-53-0C4H6N2O3
- (5-Amino-1-methyl-2,6-dioxo-1,3-diazinan-4-yl)urea5417-15-2C6H11N5O3
- 5-Chloro-6-ethoxy-5-methyldihydro-2,4(1H,3H)-pyrimidinedione50610-44-1C7H11ClN2O3
- 5-Methyl-1-propan-2-yl-1,3-diazinane-2,4-dione6306-74-7C8H14N2O2
- Hydrouracil, 1-methyl-696-11-7C5H8N2O2
- 5-Bromo-5,6-dihydro-1-methyluracil6306-81-6C5H7BrN2O2
- 5-Bromo-6-methyldihydropyrimidine-2,4(1H,3H)-dione7153-59-5C5H7BrN2O2
- 6,6-Dimethyldihydropyrimidine-2,4(1H,3H)-dione6300-94-3C6H10N2O2
- 5,5-Diethyldihydropyrimidine-2,4(1H,3H)-dione6299-60-1C8H14N2O2
- 1,5-Dimethyldihydropyrimidine-2,4(1H,3H)-dione6299-61-2C6H10N2O2
- 5,5-Diethyl-6,6-dimethoxy-1,3-diazinane-2,4-dione500348-93-6C10H18N2O4
- 1-(2-Methylpropyl)dihydropyrimidine-2,4(1H,3H)-dione6640-08-0C8H14N2O2
- 5-Ethyl-5-propyldihydropyrimidine-2,4(1H,3H)-dione6340-67-6C9H16N2O2
- 1-Butyldihydropyrimidine-2,4(1H,3H)-dione705-05-5C8H14N2O2
- 5-Bromo-1-butyldihydropyrimidine-2,4(1H,3H)-dione709-18-2C8H13BrN2O2
- 5-Bromo-1-(2,2-diethoxyethyl)-6-hydroxy-1,3-diazinane-2,4-dione7254-27-5C10H17BrN2O5
- 1-(Propan-2-yl)-1,3-diazinane-2,4-dione700-39-0C7H12N2O2
- 5-Chloro-6-methoxy-5,6-dihydrothymine98140-01-3C6H9ClN2O3
- 5,5-Difluoro-6-hydroxydihydropyrimidine-2,4(1H,3H)-dione55052-50-1C4H4F2N2O3
- 2,4(1H,3H)-Pyrimidinedione, dihydro-6-(acetyloxy)-5-methyl-5-nitro-82531-52-0C7H9N3O6
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1cccc[nH]1](/scaffold/UBQKCCHYAOITMY-UHFFFAOYSA-N/structure.svg)
