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Murcko scaffold

6-Phenyl-5H-pyrrolo[2,3-b]pyrazine scaffold

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
27
With full pages
4
Scaffold SMILES

c1ccc(-c2cc3nccnc3[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Phenyl-5H-pyrrolo[2,3-b]pyrazine page
Murcko scaffold c1ccc(-c2cc3nccnc3[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

6-Phenyl-5H-pyrrolo[2,3-b]pyrazine chemical structure, C12H9N3, CAS 78605-10-4
6-Phenyl-5H-pyrrolo[2,3-b]pyrazine
CAS 78605-10-4C12H9N3
RefChem:883882 chemical structure, C16H17N3O, CAS 496864-16-5
RefChem:883882
CAS 496864-16-5C16H17N3O
7-Butyl-6-(4-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C17H19N3O, CAS 496864-15-4
7-Butyl-6-(4-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 496864-15-4C17H19N3O
3-Methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazine chemical structure, C13H11N3, CAS 78605-13-7
3-Methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazine
CAS 78605-13-7C13H11N3
6-(2-Methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C13H11N3O, CAS 496863-95-7
6-(2-Methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 496863-95-7C13H11N3O
6-(4-Methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C13H11N3O, CAS 139962-77-9
6-(4-Methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 139962-77-9C13H11N3O
6-(4-Fluorophenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C12H8FN3, CAS 348637-66-1
6-(4-Fluorophenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 348637-66-1C12H8FN3
6-(4-Chlorophenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C12H8ClN3, CAS 139962-78-0
6-(4-Chlorophenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 139962-78-0C12H8ClN3
6-(4-Bromophenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C12H8BrN3, CAS 348637-26-3
6-(4-Bromophenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 348637-26-3C12H8BrN3
6-[4-(Trifluoromethyl)phenyl]-5H-pyrrolo[2,3-b]pyrazine chemical structure, C13H8F3N3, CAS 496864-01-8
6-[4-(Trifluoromethyl)phenyl]-5H-pyrrolo[2,3-b]pyrazine
CAS 496864-01-8C13H8F3N3
6-(4-Methylphenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C13H11N3, CAS 496864-03-0
6-(4-Methylphenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 496864-03-0C13H11N3
6-(3,4-Dimethoxyphenyl)-7-methyl-5H-pyrrolo[2,3-b]pyrazine chemical structure, C15H15N3O2, CAS 655239-15-9
6-(3,4-Dimethoxyphenyl)-7-methyl-5H-pyrrolo[2,3-b]pyrazine
CAS 655239-15-9C15H15N3O2
Aloisine B chemical structure, C15H14ClN3, CAS 496864-14-3
Aloisine B
CAS 496864-14-3C15H14ClN3
7-Butyl-6-(4-chlorophenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C16H16ClN3, CAS 496864-17-6
7-Butyl-6-(4-chlorophenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 496864-17-6C16H16ClN3
6-(3-Bromophenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C12H8BrN3, CAS 348637-24-1
6-(3-Bromophenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 348637-24-1C12H8BrN3
6-(4-(Trifluoromethoxy)phenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C13H8F3N3O, CAS 479551-49-0
6-(4-(Trifluoromethoxy)phenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 479551-49-0C13H8F3N3O
6-(3,4-Dimethoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C14H13N3O2, CAS 348637-50-3
6-(3,4-Dimethoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 348637-50-3C14H13N3O2
6-(2-(Trifluoromethyl)phenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C13H8F3N3, CAS 798544-35-1
6-(2-(Trifluoromethyl)phenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 798544-35-1C13H8F3N3
6-(2-Chlorophenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C12H8ClN3, CAS 124005-73-8
6-(2-Chlorophenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 124005-73-8C12H8ClN3
5-Methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid chemical structure, C14H11N3O2, CAS 521985-06-8
5-Methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid
CAS 521985-06-8C14H11N3O2
2-(4-(7-Ethyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenyl)propan-2-ol chemical structure, C17H19N3O, CAS 1011732-96-9
2-(4-(7-Ethyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenyl)propan-2-ol
CAS 1011732-96-9C17H19N3O
6-(o-Tolyl)-4H-pyrrolo[2,3-b]pyrazine chemical structure, C13H11N3, CAS 798544-38-4
6-(o-Tolyl)-4H-pyrrolo[2,3-b]pyrazine
CAS 798544-38-4C13H11N3
6-(2-Fluorophenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C12H8FN3, CAS 798544-37-3
6-(2-Fluorophenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 798544-37-3C12H8FN3
2-Bromo-6-(2-chloro-phenyl)-5H-pyrrolo[2,3-b]pyrazine chemical structure, C12H7BrClN3, CAS 1443750-41-1
2-Bromo-6-(2-chloro-phenyl)-5H-pyrrolo[2,3-b]pyrazine
CAS 1443750-41-1C12H7BrClN3