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Murcko scaffold

4,5,6,7-Tetrahydropyrazolo(1,5-a)pyrazine scaffold

512 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
512
With full pages
62
Scaffold SMILES

c1cc2n(n1)CCNC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4,5,6,7-Tetrahydropyrazolo(1,5-a)pyrazine page
Murcko scaffold c1cc2n(n1)CCNC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 512 chemicals

5-Methyl-4H,6H,7H-pyrazolo[1,5-a]pyrazine chemical structure, C7H11N3, CAS 2845127-88-8
5-Methyl-4H,6H,7H-pyrazolo[1,5-a]pyrazine
CAS 2845127-88-8C7H11N3
4,5,6,7-Tetrahydropyrazolo(1,5-a)pyrazine chemical structure, C6H9N3, CAS 792163-25-8
4,5,6,7-Tetrahydropyrazolo(1,5-a)pyrazine
CAS 792163-25-8C6H9N3
(4,5,6,7-Tetrahydropyrazolo[1,5-A]pyrazin-2-yl)methanol chemical structure, C7H11N3O, CAS 623565-69-5
(4,5,6,7-Tetrahydropyrazolo[1,5-A]pyrazin-2-yl)methanol
CAS 623565-69-5C7H11N3O
2-Methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine chemical structure, C7H11N3, CAS 1209273-29-9
2-Methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine
CAS 1209273-29-9C7H11N3
4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrazine-2-carbonitrile chemical structure, C7H8N4, CAS 1208491-86-4
4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrazine-2-carbonitrile
CAS 1208491-86-4C7H8N4
Ethyl 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate chemical structure, C9H13N3O2, CAS 1029720-98-6
Ethyl 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate
CAS 1029720-98-6C9H13N3O2
4,5,6,7-Tetrahydro-2-(trifluoromethyl)-pyrazolo(1,5-a)pyrazine chemical structure, C7H8F3N3, CAS 1196154-97-8
4,5,6,7-Tetrahydro-2-(trifluoromethyl)-pyrazolo(1,5-a)pyrazine
CAS 1196154-97-8C7H8F3N3
Ethyl 4,5,6,7-tetrahydropyrazolo[1,5-A]pyrazine-3-carboxylate chemical structure, C9H13N3O2, CAS 1060814-45-0
Ethyl 4,5,6,7-tetrahydropyrazolo[1,5-A]pyrazine-3-carboxylate
CAS 1060814-45-0C9H13N3O2
4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid chemical structure, C7H9N3O2, CAS 1309128-62-8
4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid
CAS 1309128-62-8C7H9N3O2
5-Ethyl-2-nitro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine chemical structure, C8H12N4O2, CAS 1346676-00-3
5-Ethyl-2-nitro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine
CAS 1346676-00-3C8H12N4O2
5-Methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-2-amine chemical structure, C7H12N4, CAS 1227210-33-4
5-Methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-2-amine
CAS 1227210-33-4C7H12N4
5-Ethyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-amine chemical structure, C8H14N4, CAS 1346676-02-5
5-Ethyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-amine
CAS 1346676-02-5C8H14N4
1-(2-Amino-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl)ethanone chemical structure, C8H12N4O, CAS 1333508-99-8
1-(2-Amino-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl)ethanone
CAS 1333508-99-8C8H12N4O
5-Methyl-2-nitro-4,5,6,7-tetrahydropyrazolo[1,5-A]pyrazine chemical structure, C7H10N4O2, CAS 1227210-32-3
5-Methyl-2-nitro-4,5,6,7-tetrahydropyrazolo[1,5-A]pyrazine
CAS 1227210-32-3C7H10N4O2
2-Nitro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine chemical structure, C6H8N4O2, CAS 1333508-96-5
2-Nitro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine
CAS 1333508-96-5C6H8N4O2
5-Boc-4,5,6,7-tetrahydro-pyrazolo[1,5-A]pyrazine chemical structure, C11H17N3O2, CAS 165894-06-4
5-Boc-4,5,6,7-tetrahydro-pyrazolo[1,5-A]pyrazine
CAS 165894-06-4C11H17N3O2
tert-Butyl 2-amino-6,7-dihydropyrazolo[1,5-A]pyrazine-5(4H)-carboxylate chemical structure, C11H18N4O2, CAS 1209487-56-8
tert-Butyl 2-amino-6,7-dihydropyrazolo[1,5-A]pyrazine-5(4H)-carboxylate
CAS 1209487-56-8C11H18N4O2
tert-Butyl 2-methyl-6,7-dihydropyrazolo[1,5-A]pyrazine-5(4H)-carboxylate chemical structure, C12H19N3O2, CAS 2295988-25-7
tert-Butyl 2-methyl-6,7-dihydropyrazolo[1,5-A]pyrazine-5(4H)-carboxylate
CAS 2295988-25-7C12H19N3O2
2-(tert-Butyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine chemical structure, C10H17N3, CAS 1250444-05-3
2-(tert-Butyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine
CAS 1250444-05-3C10H17N3
4,5,6,7-Tetrahydro-4-methylpyrazolo[1,5-a]pyrazine chemical structure, C7H11N3, CAS 1174645-29-4
4,5,6,7-Tetrahydro-4-methylpyrazolo[1,5-a]pyrazine
CAS 1174645-29-4C7H11N3
5-(tert-Butyl) 2-methyl 6,7-dihydropyrazolo[1,5-a]pyrazine-2,5(4H)-dicarboxylate chemical structure, C13H19N3O4, CAS 1209492-72-7
5-(tert-Butyl) 2-methyl 6,7-dihydropyrazolo[1,5-a]pyrazine-2,5(4H)-dicarboxylate
CAS 1209492-72-7C13H19N3O4
5-[(tert-Butoxy)carbonyl]-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine-2-carboxylic acid chemical structure, C12H17N3O4, CAS 1209492-73-8
5-[(tert-Butoxy)carbonyl]-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine-2-carboxylic acid
CAS 1209492-73-8C12H17N3O4
Ethyl 4,5,6,7-tetrahydro-5-methylpyrazolo[1,5-a]pyrazine-2-carboxylate chemical structure, C10H15N3O2, CAS 1065066-07-0
Ethyl 4,5,6,7-tetrahydro-5-methylpyrazolo[1,5-a]pyrazine-2-carboxylate
CAS 1065066-07-0C10H15N3O2
5-Methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid chemical structure, C8H11N3O2, CAS 1065331-08-9
5-Methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid
CAS 1065331-08-9C8H11N3O2