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Murcko scaffold

Phenyl-5-thiazolylmethanone scaffold

94 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
94
With full pages
16
Scaffold SMILES

O=C(c1ccccc1)c1cncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Phenyl-5-thiazolylmethanone page
Murcko scaffold O=C(c1ccccc1)c1cncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 94 chemicals

(4-Amino-2-ethoxy-1,3-thiazol-5-yl)(3,4-dihydroxyphenyl)methanone chemical structure, C12H12N2O4S, CAS 89779-23-7
(4-Amino-2-ethoxy-1,3-thiazol-5-yl)(3,4-dihydroxyphenyl)methanone
CAS 89779-23-7C12H12N2O4S
[4-Amino-2-(ethylamino)-5-thiazolyl]phenylmethanone chemical structure, C12H13N3OS, CAS 107401-75-2
[4-Amino-2-(ethylamino)-5-thiazolyl]phenylmethanone
CAS 107401-75-2C12H13N3OS
[4-Amino-2-(methylsulfanyl)-1,3-thiazol-5-yl](phenyl)methanone chemical structure, C11H10N2OS2, CAS 39736-27-1
[4-Amino-2-(methylsulfanyl)-1,3-thiazol-5-yl](phenyl)methanone
CAS 39736-27-1C11H10N2OS2
[4-Amino-2-(methylamino)-1,3-thiazol-5-yl](phenyl)methanone chemical structure, C11H11N3OS, CAS 107401-74-1
[4-Amino-2-(methylamino)-1,3-thiazol-5-yl](phenyl)methanone
CAS 107401-74-1C11H11N3OS
(4-Amino-2-(methylamino)thiazol-5-yl)(p-tolyl)methanone chemical structure, C12H13N3OS, CAS 674805-68-6
(4-Amino-2-(methylamino)thiazol-5-yl)(p-tolyl)methanone
CAS 674805-68-6C12H13N3OS
(4-Bromophenyl)(2-(methylamino)-5-thiazolyl)methanone chemical structure, C11H9BrN2OS, CAS 339008-24-1
(4-Bromophenyl)(2-(methylamino)-5-thiazolyl)methanone
CAS 339008-24-1C11H9BrN2OS
[4-Amino-2-(tert-butylamino)-1,3-thiazol-5-yl](4-chlorophenyl)methanone chemical structure, C14H16ClN3OS, CAS 339020-27-8
[4-Amino-2-(tert-butylamino)-1,3-thiazol-5-yl](4-chlorophenyl)methanone
CAS 339020-27-8C14H16ClN3OS
[4-Amino-2-(tert-butylamino)-1,3-thiazol-5-yl](4-methylphenyl)methanone chemical structure, C15H19N3OS, CAS 339020-30-3
[4-Amino-2-(tert-butylamino)-1,3-thiazol-5-yl](4-methylphenyl)methanone
CAS 339020-30-3C15H19N3OS
(4-Amino-2-(tert-butylamino)-1,3-thiazol-5-yl)(phenyl)methanone chemical structure, C14H17N3OS, CAS 339020-31-4
(4-Amino-2-(tert-butylamino)-1,3-thiazol-5-yl)(phenyl)methanone
CAS 339020-31-4C14H17N3OS
[4-Amino-2-(tert-butylamino)-1,3-thiazol-5-yl](4-bromophenyl)methanone chemical structure, C14H16BrN3OS, CAS 339020-32-5
[4-Amino-2-(tert-butylamino)-1,3-thiazol-5-yl](4-bromophenyl)methanone
CAS 339020-32-5C14H16BrN3OS
(4-Chlorophenyl)[2-(methylamino)-1,3-thiazol-5-yl]methanone chemical structure, C11H9ClN2OS, CAS 299175-15-8
(4-Chlorophenyl)[2-(methylamino)-1,3-thiazol-5-yl]methanone
CAS 299175-15-8C11H9ClN2OS
(4-Fluorophenyl)[2-(methylamino)-1,3-thiazol-5-yl]methanone chemical structure, C11H9FN2OS, CAS 339021-39-5
(4-Fluorophenyl)[2-(methylamino)-1,3-thiazol-5-yl]methanone
CAS 339021-39-5C11H9FN2OS
(2,4-Dichlorophenyl)(2-(methylamino)-1,3-thiazol-5-yl)methanone chemical structure, C11H8Cl2N2OS, CAS 339021-41-9
(2,4-Dichlorophenyl)(2-(methylamino)-1,3-thiazol-5-yl)methanone
CAS 339021-41-9C11H8Cl2N2OS
(3,4-Dichlorophenyl)[2-(methylamino)-1,3-thiazol-5-yl]methanone chemical structure, C11H8Cl2N2OS, CAS 339022-12-7
(3,4-Dichlorophenyl)[2-(methylamino)-1,3-thiazol-5-yl]methanone
CAS 339022-12-7C11H8Cl2N2OS
[2-(Methylamino)-1,3-thiazol-5-yl](phenyl)methanone chemical structure, C11H10N2OS, CAS 339022-14-9
[2-(Methylamino)-1,3-thiazol-5-yl](phenyl)methanone
CAS 339022-14-9C11H10N2OS
[4-Amino-2-(tert-butylamino)-1,3-thiazol-5-yl](2,4-dichlorophenyl)methanone chemical structure, C14H15Cl2N3OS, CAS 339106-66-0
[4-Amino-2-(tert-butylamino)-1,3-thiazol-5-yl](2,4-dichlorophenyl)methanone
CAS 339106-66-0C14H15Cl2N3OS
[4-Amino-2-(tert-butylamino)-1,3-thiazol-5-yl](4-fluorophenyl)methanone chemical structure, C14H16FN3OS, CAS 339106-68-2
[4-Amino-2-(tert-butylamino)-1,3-thiazol-5-yl](4-fluorophenyl)methanone
CAS 339106-68-2C14H16FN3OS
[4-Amino-2-(methylamino)-1,3-thiazol-5-yl]-(4-chlorophenyl)methanone chemical structure, C11H10ClN3OS, CAS 204188-38-5
[4-Amino-2-(methylamino)-1,3-thiazol-5-yl]-(4-chlorophenyl)methanone
CAS 204188-38-5C11H10ClN3OS
[4-Amino-2-(prop-2-en-1-ylamino)-1,3-thiazol-5-yl](phenyl)methanone chemical structure, C13H13N3OS, CAS 13807-12-0
[4-Amino-2-(prop-2-en-1-ylamino)-1,3-thiazol-5-yl](phenyl)methanone
CAS 13807-12-0C13H13N3OS
[2-(Allylamino)-4-amino-1,3-thiazol-5-yl](4-fluorophenyl)methanone chemical structure, C13H12FN3OS, CAS 339019-99-7
[2-(Allylamino)-4-amino-1,3-thiazol-5-yl](4-fluorophenyl)methanone
CAS 339019-99-7C13H12FN3OS
[2-(Allylamino)-4-amino-1,3-thiazol-5-yl](4-chlorophenyl)methanone chemical structure, C13H12ClN3OS, CAS 328282-18-4
[2-(Allylamino)-4-amino-1,3-thiazol-5-yl](4-chlorophenyl)methanone
CAS 328282-18-4C13H12ClN3OS
[2-(Allylamino)-4-amino-1,3-thiazol-5-yl](4-nitrophenyl)methanone chemical structure, C13H12N4O3S, CAS 478247-68-6
[2-(Allylamino)-4-amino-1,3-thiazol-5-yl](4-nitrophenyl)methanone
CAS 478247-68-6C13H12N4O3S
[2-(Allylamino)-4-amino-1,3-thiazol-5-yl][3-(trifluoromethyl)phenyl]methanone chemical structure, C14H12F3N3OS, CAS 339020-05-2
[2-(Allylamino)-4-amino-1,3-thiazol-5-yl][3-(trifluoromethyl)phenyl]methanone
CAS 339020-05-2C14H12F3N3OS
N'-[5-(4-Chlorobenzoyl)-1,3-thiazol-2-yl]-N,N-dimethylmethanimidamide chemical structure, C13H12ClN3OS
N'-[5-(4-Chlorobenzoyl)-1,3-thiazol-2-yl]-N,N-dimethylmethanimidamide
C13H12ClN3OS