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Murcko scaffold

Phenyl-5-thiazolylmethanone scaffold

94 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
94
With full pages
16
Scaffold SMILES

O=C(c1ccccc1)c1cncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Phenyl-5-thiazolylmethanone page
Murcko scaffold O=C(c1ccccc1)c1cncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 94 of 94 chemicals

Methyl 5-benzoyl-2-methyl-1,3-thiazole-4-carboxylate chemical structure, C13H11NO3S, CAS 920113-32-2
Methyl 5-benzoyl-2-methyl-1,3-thiazole-4-carboxylate
CAS 920113-32-2C13H11NO3S
(4-Bromophenyl)(thiazol-5-yl)methanone chemical structure, C10H6BrNOS, CAS 91516-30-2
(4-Bromophenyl)(thiazol-5-yl)methanone
CAS 91516-30-2C10H6BrNOS
Methyl 5-(4-ethylbenzoyl)-2-methyl-1,3-thiazole-4-carboxylate chemical structure, C15H15NO3S, CAS 1105193-72-3
Methyl 5-(4-ethylbenzoyl)-2-methyl-1,3-thiazole-4-carboxylate
CAS 1105193-72-3C15H15NO3S
5-Benzoyl-2-methyl-1,3-thiazole-4-carboxylic acid chemical structure, C12H9NO3S, CAS 32002-71-4
5-Benzoyl-2-methyl-1,3-thiazole-4-carboxylic acid
CAS 32002-71-4C12H9NO3S
5-(4-Fluorobenzoyl)-2-methyl-1,3-thiazole-4-carboxylic acid chemical structure, C12H8FNO3S, CAS 941868-40-2
5-(4-Fluorobenzoyl)-2-methyl-1,3-thiazole-4-carboxylic acid
CAS 941868-40-2C12H8FNO3S
Methyl 2-amino-5-(4-chlorobenzoyl)-1,3-thiazole-4-carboxylate chemical structure, C12H9ClN2O3S, CAS 941868-44-6
Methyl 2-amino-5-(4-chlorobenzoyl)-1,3-thiazole-4-carboxylate
CAS 941868-44-6C12H9ClN2O3S
Methyl 2-amino-5-(4-fluorobenzoyl)-1,3-thiazole-4-carboxylate chemical structure, C12H9FN2O3S, CAS 941868-46-8
Methyl 2-amino-5-(4-fluorobenzoyl)-1,3-thiazole-4-carboxylate
CAS 941868-46-8C12H9FN2O3S
Methyl 2-amino-5-(4-methoxybenzoyl)-1,3-thiazole-4-carboxylate chemical structure, C13H12N2O4S, CAS 941868-48-0
Methyl 2-amino-5-(4-methoxybenzoyl)-1,3-thiazole-4-carboxylate
CAS 941868-48-0C13H12N2O4S
(2-Methyl-5-thiazolyl)phenylmethanone chemical structure, C11H9NOS, CAS 20155-88-8
(2-Methyl-5-thiazolyl)phenylmethanone
CAS 20155-88-8C11H9NOS
5-[(2-Chlorophenyl)carbonyl]-1,3-thiazol-2-amine chemical structure, C10H7ClN2OS, CAS 848462-68-0
5-[(2-Chlorophenyl)carbonyl]-1,3-thiazol-2-amine
CAS 848462-68-0C10H7ClN2OS
(2-Amino-thiazol-5-yl)-(2-methoxy-phenyl)-methanone chemical structure, C11H10N2O2S, CAS 862574-62-7
(2-Amino-thiazol-5-yl)-(2-methoxy-phenyl)-methanone
CAS 862574-62-7C11H10N2O2S
(2-Aminophenyl)-5-thiazolylmethanone chemical structure, C10H8N2OS, CAS 942190-13-8
(2-Aminophenyl)-5-thiazolylmethanone
CAS 942190-13-8C10H8N2OS
(2-Nitrophenyl)-(2-trimethylsilanylthiazol-5-yl)methanone chemical structure, C13H14N2O3SSi, CAS 942190-12-7
(2-Nitrophenyl)-(2-trimethylsilanylthiazol-5-yl)methanone
CAS 942190-12-7C13H14N2O3SSi
(2-Amino-5-chlorophenyl)-5-thiazolylmethanone chemical structure, C10H7ClN2OS, CAS 1050202-99-7
(2-Amino-5-chlorophenyl)-5-thiazolylmethanone
CAS 1050202-99-7C10H7ClN2OS
(5-Chloro-2-nitrophenyl)-5-thiazolylMethanone chemical structure, C10H5ClN2O3S, CAS 1050203-01-4
(5-Chloro-2-nitrophenyl)-5-thiazolylMethanone
CAS 1050203-01-4C10H5ClN2O3S
(2,4-Dibromothiazol-5-yl)(phenyl)methanone chemical structure, C10H5Br2NOS, CAS 960069-35-6
(2,4-Dibromothiazol-5-yl)(phenyl)methanone
CAS 960069-35-6C10H5Br2NOS
N'-[5-(4-Bromobenzoyl)-1,3-thiazol-2-yl]-N,N-dimethylmethanimidamide chemical structure, C13H12BrN3OS, CAS 528818-71-5
N'-[5-(4-Bromobenzoyl)-1,3-thiazol-2-yl]-N,N-dimethylmethanimidamide
CAS 528818-71-5C13H12BrN3OS
N,N-Dimethyl-Na(2)-[5-(4-methylbenzoyl)-2-thiazolyl]methanimidamide chemical structure, C14H15N3OS, CAS 569350-53-4
N,N-Dimethyl-Na(2)-[5-(4-methylbenzoyl)-2-thiazolyl]methanimidamide
CAS 569350-53-4C14H15N3OS
(2-Aminothiazol-5-yl)(p-tolyl)methanone chemical structure, C11H10N2OS, CAS 27053-22-1
(2-Aminothiazol-5-yl)(p-tolyl)methanone
CAS 27053-22-1C11H10N2OS
2-Chloro-5-(4-methoxybenzoyl)-4-trifluoromethyl-1,3-thiazole chemical structure, C12H7ClF3NO2S, CAS 1820648-20-1
2-Chloro-5-(4-methoxybenzoyl)-4-trifluoromethyl-1,3-thiazole
CAS 1820648-20-1C12H7ClF3NO2S
2-Chloro-5-(3-methylbenzoyl)-4-trifluoromethyl-1,3-thiazole chemical structure, C12H7ClF3NOS, CAS 1820673-97-9
2-Chloro-5-(3-methylbenzoyl)-4-trifluoromethyl-1,3-thiazole
CAS 1820673-97-9C12H7ClF3NOS
2-Chloro-5-(3-methoxybenzoyl)-4-trifluoromethyl-1,3-thiazole chemical structure, C12H7ClF3NO2S, CAS 1820640-37-6
2-Chloro-5-(3-methoxybenzoyl)-4-trifluoromethyl-1,3-thiazole
CAS 1820640-37-6C12H7ClF3NO2S
2-Chloro-5-(3-fluorobenzoyl)-4-trifluoromethyl-1,3-thiazole chemical structure, C11H4ClF4NOS, CAS 1820712-17-1
2-Chloro-5-(3-fluorobenzoyl)-4-trifluoromethyl-1,3-thiazole
CAS 1820712-17-1C11H4ClF4NOS
2-Chloro-5-(3-chlorobenzoyl)-4-trifluoromethyl-1,3-thiazole chemical structure, C11H4Cl2F3NOS, CAS 1820618-57-2
2-Chloro-5-(3-chlorobenzoyl)-4-trifluoromethyl-1,3-thiazole
CAS 1820618-57-2C11H4Cl2F3NOS