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Murcko scaffold

Ring system with 2 rings and 12 atoms

28 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
28
With full pages
3
Scaffold SMILES

O=c1cc(B2OCCO2)cc[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(B2OCCO2)cc[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

2-Hydroxypyridine-4-boronic acid, pinacol ester chemical structure, C11H16BNO3, CAS 1256358-90-3
2-Hydroxypyridine-4-boronic acid, pinacol ester
CAS 1256358-90-3C11H16BNO3
1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one chemical structure, C12H18BNO3, CAS 1160790-84-0
1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS 1160790-84-0C12H18BNO3
1-(Methyl-d3)-pyridin-2-one-4-boronic acid pinacol ester chemical structure, C12H18BNO3, CAS 2241876-08-2
1-(Methyl-d3)-pyridin-2-one-4-boronic acid pinacol ester
CAS 2241876-08-2C12H18BNO3
1-(2-Hydroxy-2-methylpropyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one chemical structure, C15H24BNO4, CAS 1400689-95-3
1-(2-Hydroxy-2-methylpropyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS 1400689-95-3C15H24BNO4
1-(2-Hydroxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one chemical structure, C13H20BNO4, CAS 1083169-02-1
1-(2-Hydroxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS 1083169-02-1C13H20BNO4
Ethyl 2-(3-chloro-2-oxo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trimethylsilyl)pyridin-1(2H)-yl)acetate chemical structure, C18H29BClNO5Si, CAS 1417647-28-9
Ethyl 2-(3-chloro-2-oxo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trimethylsilyl)pyridin-1(2H)-yl)acetate
CAS 1417647-28-9C18H29BClNO5Si
1-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one chemical structure, C14H22BNO3, CAS 2601613-43-6
1-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS 2601613-43-6C14H22BNO3
6-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one chemical structure, C12H18BNO3, CAS 2223046-45-3
6-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS 2223046-45-3C12H18BNO3
1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-pyridinone chemical structure, C13H20BNO3, CAS 1596367-33-7
1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-pyridinone
CAS 1596367-33-7C13H20BNO3
5-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one chemical structure, C11H15BClNO3, CAS 1412905-52-2
5-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS 1412905-52-2C11H15BClNO3
2-Oxo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-dihydropyridine-3-carbaldehyde chemical structure, C12H16BNO4, CAS 1356833-33-4
2-Oxo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-dihydropyridine-3-carbaldehyde
CAS 1356833-33-4C12H16BNO4
tert-Butyl 2-[2-oxo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-dihydropyridin-1-yl]acetate chemical structure, C17H26BNO5, CAS 1445962-56-0
tert-Butyl 2-[2-oxo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-dihydropyridin-1-yl]acetate
CAS 1445962-56-0C17H26BNO5
3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one chemical structure, C12H18BNO3, CAS 2641339-84-4
3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS 2641339-84-4C12H18BNO3
2-Hydroxy-6-trifluoromethylpyridine-4-boronic acid pinacol ester chemical structure, C12H15BF3NO3, CAS 2223051-19-0
2-Hydroxy-6-trifluoromethylpyridine-4-boronic acid pinacol ester
CAS 2223051-19-0C12H15BF3NO3
2-Hydroxy-5-bromopyridine-4-boronic acid pinacol ester chemical structure, C11H15BBrNO3, CAS 2223044-75-3
2-Hydroxy-5-bromopyridine-4-boronic acid pinacol ester
CAS 2223044-75-3C11H15BBrNO3
5-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one chemical structure, C11H15BFNO3, CAS 2223048-48-2
5-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS 2223048-48-2C11H15BFNO3
1,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one chemical structure, C13H20BNO3, CAS 2088451-25-4
1,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS 2088451-25-4C13H20BNO3
1-(2-Methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one chemical structure, C14H22BNO4, CAS 1598407-01-2
1-(2-Methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS 1598407-01-2C14H22BNO4
tert-Butyl [5-methoxy-2-oxo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-1(2H)-yl]acetate chemical structure, C18H28BNO6, CAS 2064122-95-6
tert-Butyl [5-methoxy-2-oxo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-1(2H)-yl]acetate
CAS 2064122-95-6C18H28BNO6
tert-Butyl 2-[5-methoxy-2-oxo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-1(2H)-yl]pentanoate chemical structure, C21H34BNO6, CAS 2064122-85-4
tert-Butyl 2-[5-methoxy-2-oxo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-1(2H)-yl]pentanoate
CAS 2064122-85-4C21H34BNO6
3-Chloro-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-one chemical structure, C12H17BClNO3, CAS 2172654-59-8
3-Chloro-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-one
CAS 2172654-59-8C12H17BClNO3
1-(2.2-Difluoroethyl)-4-(4.4.5.5-tetramethyl-1.3.2-dioxaborolan-2-yl)pyridin-2(1H)-one chemical structure, C13H18BF2NO3, CAS 2509138-06-9
1-(2.2-Difluoroethyl)-4-(4.4.5.5-tetramethyl-1.3.2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS 2509138-06-9C13H18BF2NO3
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-one chemical structure, C13H17BF3NO3, CAS 2509138-07-0
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-one
CAS 2509138-07-0C13H17BF3NO3
3-Fluoro-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one chemical structure, C12H17BFNO3, CAS 2866420-32-6
3-Fluoro-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS 2866420-32-6C12H17BFNO3