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Murcko scaffold

Ring system with 2 rings and 21 atoms

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
21
Chemicals
14
With full pages
4
Scaffold SMILES

O=C(CNC(=O)c1ccccc1)NCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)c1ccccc1)NCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

4-Hydroxybenzoylglycylphenylalanine chemical structure, C18H18N2O5, CAS 92279-08-8
4-Hydroxybenzoylglycylphenylalanine
CAS 92279-08-8C18H18N2O5
Hippuryl-phenylalanyl-arginine chemical structure, C24H30N6O5, CAS 73167-83-6
Hippuryl-phenylalanyl-arginine
CAS 73167-83-6C24H30N6O5
Methyl 2-[[2-[[2-[(2-hydroxybenzoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]acetate chemical structure, C21H23N3O6, CAS 78397-59-8
Methyl 2-[[2-[[2-[(2-hydroxybenzoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]acetate
CAS 78397-59-8C21H23N3O6
N-[2-[2-(4-Chlorophenyl)ethylamino]-2-oxoethyl]-2-fluorobenzamide chemical structure, C17H16ClFN2O2, CAS 851723-55-2
N-[2-[2-(4-Chlorophenyl)ethylamino]-2-oxoethyl]-2-fluorobenzamide
CAS 851723-55-2C17H16ClFN2O2
N-{3-Methyl-1-oxo-1-[(2-phenylethyl)amino]butan-2-yl}benzamide chemical structure, C20H24N2O2, CAS 1100118-65-7
N-{3-Methyl-1-oxo-1-[(2-phenylethyl)amino]butan-2-yl}benzamide
CAS 1100118-65-7C20H24N2O2
4-Ethyl-N-{4-(methylsulfanyl)-1-oxo-1-[(2-phenylethyl)amino]butan-2-yl}benzamide chemical structure, C22H28N2O2S, CAS 1008036-33-6
4-Ethyl-N-{4-(methylsulfanyl)-1-oxo-1-[(2-phenylethyl)amino]butan-2-yl}benzamide
CAS 1008036-33-6C22H28N2O2S
Lophyrotomin chemical structure, C48H65N9O17, CAS 85932-85-0
Lophyrotomin
CAS 85932-85-0C48H65N9O17
(S)-2-(2-Benzamidoacetamido)-3-phenylpropanoic acid chemical structure, C18H18N2O4, CAS 744-59-2
(S)-2-(2-Benzamidoacetamido)-3-phenylpropanoic acid
CAS 744-59-2C18H18N2O4
p-Hydroxybenzoyl-L-alanyl-L-phenylalanine chemical structure, C19H20N2O5, CAS 92279-13-5
p-Hydroxybenzoyl-L-alanyl-L-phenylalanine
CAS 92279-13-5C19H20N2O5
L-Phenylalanine, N-benzoyl-L-leucyl- chemical structure, C22H26N2O4, CAS 193280-26-1
L-Phenylalanine, N-benzoyl-L-leucyl-
CAS 193280-26-1C22H26N2O4
N-[2-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-2-oxoethyl]-2-methylbenzamide chemical structure, C20H24N2O4, CAS 1060809-38-2
N-[2-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-2-oxoethyl]-2-methylbenzamide
CAS 1060809-38-2C20H24N2O4
2-Bromo-N-[2-[[2-(4-fluorophenyl)ethyl]amino]-2-oxoethyl]benzamide chemical structure, C17H16BrFN2O2, CAS 1060817-33-5
2-Bromo-N-[2-[[2-(4-fluorophenyl)ethyl]amino]-2-oxoethyl]benzamide
CAS 1060817-33-5C17H16BrFN2O2
Bz-Gly-Phe-Arg-NH2 chemical structure, C24H31N7O4, CAS 88492-30-2
Bz-Gly-Phe-Arg-NH2
CAS 88492-30-2C24H31N7O4
N-Benzoyl-D-alanyl-D-phenylalaninamide chemical structure, C19H21N3O3, CAS 527752-00-7
N-Benzoyl-D-alanyl-D-phenylalaninamide
CAS 527752-00-7C19H21N3O3