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Murcko scaffold

Ring system with 3 rings and 24 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
15
With full pages
8
Scaffold SMILES

O=C(CCn1cncn1)N1CCN(S(=O)(=O)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCn1cncn1)N1CCN(S(=O)(=O)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

1-[4-(4-Methylbenzenesulfonyl)piperazin-1-yl]-3-(1H-1,2,4-triazol-1-yl)propan-1-one chemical structure, C16H21N5O3S, CAS 835893-85-1
1-[4-(4-Methylbenzenesulfonyl)piperazin-1-yl]-3-(1H-1,2,4-triazol-1-yl)propan-1-one
CAS 835893-85-1C16H21N5O3S
3-(3,5-Dimethyl-1,2,4-triazol-1-yl)-1-[4-(2,4,6-trimethylphenyl)sulfonylpiperazin-1-yl]butan-1-one chemical structure, C21H31N5O3S, CAS 890594-44-2
3-(3,5-Dimethyl-1,2,4-triazol-1-yl)-1-[4-(2,4,6-trimethylphenyl)sulfonylpiperazin-1-yl]butan-1-one
CAS 890594-44-2C21H31N5O3S
1-[4-(3,4-Dimethyl-benzenesulfonyl)-piperazin-1-yl]-3-[1,2,4]triazol-1-yl-propan-1-one chemical structure, C17H23N5O3S, CAS 878682-85-0
1-[4-(3,4-Dimethyl-benzenesulfonyl)-piperazin-1-yl]-3-[1,2,4]triazol-1-yl-propan-1-one
CAS 878682-85-0C17H23N5O3S
1-[4-(4-Chloro-benzenesulfonyl)-piperazin-1-yl]-3-[1,2,4]triazol-1-yl-propan-1-one chemical structure, C15H18ClN5O3S, CAS 878682-87-2
1-[4-(4-Chloro-benzenesulfonyl)-piperazin-1-yl]-3-[1,2,4]triazol-1-yl-propan-1-one
CAS 878682-87-2C15H18ClN5O3S
1-[3-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)-2-methylpropanoyl]-4-(phenylsulfonyl)piperazine chemical structure, C18H25N5O3S, CAS 879056-22-1
1-[3-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)-2-methylpropanoyl]-4-(phenylsulfonyl)piperazine
CAS 879056-22-1C18H25N5O3S
2-Methyl-3-(1,2,4-triazol-1-yl)-1-[4-(2,4,6-trimethylphenyl)sulfonylpiperazin-1-yl]propan-1-one chemical structure, C19H27N5O3S, CAS 879056-34-5
2-Methyl-3-(1,2,4-triazol-1-yl)-1-[4-(2,4,6-trimethylphenyl)sulfonylpiperazin-1-yl]propan-1-one
CAS 879056-34-5C19H27N5O3S
1-[(4-Methylphenyl)sulfonyl]-4-[2-methyl-3-(1H-1,2,4-triazol-1-yl)propanoyl]piperazine chemical structure, C17H23N5O3S, CAS 879056-40-3
1-[(4-Methylphenyl)sulfonyl]-4-[2-methyl-3-(1H-1,2,4-triazol-1-yl)propanoyl]piperazine
CAS 879056-40-3C17H23N5O3S
1-(4-((3,4-Dimethylphenyl)sulfonyl)piperazin-1-yl)-2-methyl-3-(1H-1,2,4-triazol-1-yl)propan-1-one chemical structure, C18H25N5O3S, CAS 879056-47-0
1-(4-((3,4-Dimethylphenyl)sulfonyl)piperazin-1-yl)-2-methyl-3-(1H-1,2,4-triazol-1-yl)propan-1-one
CAS 879056-47-0C18H25N5O3S
1-[2-Methyl-3-(1H-1,2,4-triazol-1-yl)propanoyl]-4-(phenylsulfonyl)piperazine chemical structure, C16H21N5O3S, CAS 879056-53-8
1-[2-Methyl-3-(1H-1,2,4-triazol-1-yl)propanoyl]-4-(phenylsulfonyl)piperazine
CAS 879056-53-8C16H21N5O3S
1-(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)-2-methyl-3-(1H-1,2,4-triazol-1-yl)propan-1-one chemical structure, C16H20ClN5O3S, CAS 879056-59-4
1-(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)-2-methyl-3-(1H-1,2,4-triazol-1-yl)propan-1-one
CAS 879056-59-4C16H20ClN5O3S
1-[(3,4-Dimethylphenyl)sulfonyl]-4-[3-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)-2-methylpropanoyl]piperazine chemical structure, C20H29N5O3S, CAS 890603-61-9
1-[(3,4-Dimethylphenyl)sulfonyl]-4-[3-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)-2-methylpropanoyl]piperazine
CAS 890603-61-9C20H29N5O3S
3-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)-2-methyl-1-(4-tosylpiperazin-1-yl)propan-1-one chemical structure, C19H27N5O3S, CAS 890603-57-3
3-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)-2-methyl-1-(4-tosylpiperazin-1-yl)propan-1-one
CAS 890603-57-3C19H27N5O3S
1-[4-(Benzenesulfonyl)piperazin-1-yl]-3-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)butan-1-one chemical structure, C18H25N5O3S, CAS 896087-22-2
1-[4-(Benzenesulfonyl)piperazin-1-yl]-3-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)butan-1-one
CAS 896087-22-2C18H25N5O3S
3-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)-1-[4-(4-methylbenzenesulfonyl)piperazin-1-yl]butan-1-one chemical structure, C19H27N5O3S, CAS 896087-14-2
3-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)-1-[4-(4-methylbenzenesulfonyl)piperazin-1-yl]butan-1-one
CAS 896087-14-2C19H27N5O3S
1-(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)-3-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)butan-1-one chemical structure, C18H24ClN5O3S, CAS 896087-44-8
1-(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)-3-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)butan-1-one
CAS 896087-44-8C18H24ClN5O3S