Murcko scaffold
Ring system with 2 rings and 20 atoms
14 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 20
- Chemicals
- 14
- With full pages
- 1
Scaffold SMILES
O=C(Cc1ccccc1)NS(=O)(=O)Oc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 14 of 14 chemicals
Avasimibe
CAS 166518-60-1C29H43NO4S
Acat-IN-7
CAS 199984-38-8C32H49N3O5S
Acat-IN-5
CAS 199983-93-2C32H49N3O5S
Acat-IN-2
CAS 199984-55-9C29H44N2O4S
Acat-IN-6
CAS 454203-45-3C31H47N3O5S
Acat-IN-9
CAS 199984-40-2C33H51N3O5S
ACAT-IN-4 (hydrochloride)
CAS 199984-46-8C32H51ClN2O5S
Acat-IN-4
CAS 454203-56-6C32H50N2O5S
Avasimibe sodium
CAS 166518-61-2C29H42NNaO4S
Acat-IN-8
CAS 199984-35-5C32H49N3O5S
ACAT-IN-10 dihydrochloride
CAS 199983-77-2C35H58Cl2N4O5S
Acat-IN-10
CAS 454203-40-8C35H56N4O5S
Acat-IN-3
CAS 454203-25-9C25H36N2O6S
Avasimibe-13C6
CAS 324016-61-7C29H43NO4S
Related scaffolds
Same ring framework with different atoms or bond orders
S=C(NN=Cc1ccccc1)Nc1ccccc1105 chemicals
S=C(NCCc1ccccc1)Nc1ccccc160 chemicals
c1ccc(CCNCCc2ccccc2)cc158 chemicals
O=C(COc1ccccc1)NCc1ccccc146 chemicals
O=C(NCCOc1ccccc1)c1ccccc146 chemicals
O=C(C=Cc1ccccc1)NCc1ccccc143 chemicals
c1ccc(OCCCOc2ccccc2)cc141 chemicals
O=C(CC(=O)Nc1ccccc1)Nc1ccccc137 chemicals
O=C(CNS(=O)(=O)c1ccccc1)Nc1ccccc136 chemicals
O=C(CSCc1ccccc1)Nc1ccccc133 chemicals
O=C(Cc1ccccc1)NCCc1ccccc132 chemicals
O=C(CNCc1ccccc1)Nc1ccccc131 chemicals