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Murcko scaffold

Ring system with 2 rings and 12 atoms

26 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
26
With full pages
3
Scaffold SMILES

O=C(c1ccc[nH]1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccc[nH]1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

2-Chloro-1-(5-(pyrrolidine-1-carbonyl)-1H-pyrrol-3-yl)ethan-1-one chemical structure, C11H13ClN2O2, CAS 873790-25-1
2-Chloro-1-(5-(pyrrolidine-1-carbonyl)-1H-pyrrol-3-yl)ethan-1-one
CAS 873790-25-1C11H13ClN2O2
5-(Pyrrolidine-1-carbonyl)-1H-pyrrole-3-carboxylic acid chemical structure, C10H12N2O3, CAS 923113-44-4
5-(Pyrrolidine-1-carbonyl)-1H-pyrrole-3-carboxylic acid
CAS 923113-44-4C10H12N2O3
4-Bromo-2-(pyrrolidine-1-carbonyl)-1H-pyrrole chemical structure, C9H11BrN2O, CAS 1031501-36-6
4-Bromo-2-(pyrrolidine-1-carbonyl)-1H-pyrrole
CAS 1031501-36-6C9H11BrN2O
5-(Pyrrolidine-1-carbonyl)-1H-pyrrole-3-sulfonamide chemical structure, C9H13N3O3S, CAS 1497805-13-6
5-(Pyrrolidine-1-carbonyl)-1H-pyrrole-3-sulfonamide
CAS 1497805-13-6C9H13N3O3S
5-(Pyrrolidine-1-carbonyl)-1H-pyrrole-3-sulfonyl chloride chemical structure, C9H11ClN2O3S, CAS 950094-39-0
5-(Pyrrolidine-1-carbonyl)-1H-pyrrole-3-sulfonyl chloride
CAS 950094-39-0C9H11ClN2O3S
5-(Pyrrolidine-1-carbonyl)-1H-pyrrol-3-amine chemical structure, C9H13N3O, CAS 1156706-14-7
5-(Pyrrolidine-1-carbonyl)-1H-pyrrol-3-amine
CAS 1156706-14-7C9H13N3O
(4-Iodo-1-boc-pyrrol-2-yl)(pyrrolidin-1-yl)methanone chemical structure, C14H19IN2O3, CAS 845868-14-6
(4-Iodo-1-boc-pyrrol-2-yl)(pyrrolidin-1-yl)methanone
CAS 845868-14-6C14H19IN2O3
(4-Iodo-1H-pyrrol-2-yl)(pyrrolidin-1-yl)methanone chemical structure, C9H11IN2O, CAS 845868-13-5
(4-Iodo-1H-pyrrol-2-yl)(pyrrolidin-1-yl)methanone
CAS 845868-13-5C9H11IN2O
(4-Ethynyl-1-boc-pyrrol-2-yl)(pyrrolidin-1-yl)methanone chemical structure, C16H20N2O3, CAS 845868-17-9
(4-Ethynyl-1-boc-pyrrol-2-yl)(pyrrolidin-1-yl)methanone
CAS 845868-17-9C16H20N2O3
(4-Bromo-1H-pyrrol-2-yl)(3-methylpyrrolidin-1-yl)methanone chemical structure, C10H13BrN2O, CAS 1248074-61-4
(4-Bromo-1H-pyrrol-2-yl)(3-methylpyrrolidin-1-yl)methanone
CAS 1248074-61-4C10H13BrN2O
(3-Aminopyrrolidin-1-yl)(1H-pyrrol-2-yl)methanone chemical structure, C9H13N3O, CAS 1250435-03-0
(3-Aminopyrrolidin-1-yl)(1H-pyrrol-2-yl)methanone
CAS 1250435-03-0C9H13N3O
1-(1-Methyl-1H-pyrrole-2-carbonyl)pyrrolidine-3-carboxylic acid chemical structure, C11H14N2O3, CAS 1339764-35-0
1-(1-Methyl-1H-pyrrole-2-carbonyl)pyrrolidine-3-carboxylic acid
CAS 1339764-35-0C11H14N2O3
1-(1H-Pyrrole-2-carbonyl)pyrrolidine-3-carboxylic acid chemical structure, C10H12N2O3, CAS 1343751-95-0
1-(1H-Pyrrole-2-carbonyl)pyrrolidine-3-carboxylic acid
CAS 1343751-95-0C10H12N2O3
1-(4-Chloro-1H-pyrrole-2-carbonyl)-3-methylpyrrolidine-3-carboxylic acid chemical structure, C11H13ClN2O3, CAS 1409856-65-0
1-(4-Chloro-1H-pyrrole-2-carbonyl)-3-methylpyrrolidine-3-carboxylic acid
CAS 1409856-65-0C11H13ClN2O3
5-(Pyrrolidine-1-carbonyl)-1H-pyrrol-3-amine hydrochloride chemical structure, C9H14ClN3O, CAS 1461705-55-4
5-(Pyrrolidine-1-carbonyl)-1H-pyrrol-3-amine hydrochloride
CAS 1461705-55-4C9H14ClN3O
(4-Bromo-1H-pyrrol-2-yl)(3,3-dimethylpyrrolidin-1-yl)methanone chemical structure, C11H15BrN2O, CAS 1535368-25-2
(4-Bromo-1H-pyrrol-2-yl)(3,3-dimethylpyrrolidin-1-yl)methanone
CAS 1535368-25-2C11H15BrN2O
[4-Bromo-1-(propan-2-yl)-1H-pyrrol-2-yl](2-ethyl-5-methylpyrrolidin-1-yl)methanone chemical structure, C15H23BrN2O, CAS 1558105-23-9
[4-Bromo-1-(propan-2-yl)-1H-pyrrol-2-yl](2-ethyl-5-methylpyrrolidin-1-yl)methanone
CAS 1558105-23-9C15H23BrN2O
(4-Ethynyl-1H-pyrrol-2-yl)(pyrrolidin-1-yl)methanone chemical structure, C11H12N2O, CAS 845868-16-8
(4-Ethynyl-1H-pyrrol-2-yl)(pyrrolidin-1-yl)methanone
CAS 845868-16-8C11H12N2O
(4-Bromo-1H-pyrrol-2-yl)(3-methoxypyrrolidin-1-yl)methanone chemical structure, C10H13BrN2O2, CAS 1933640-62-0
(4-Bromo-1H-pyrrol-2-yl)(3-methoxypyrrolidin-1-yl)methanone
CAS 1933640-62-0C10H13BrN2O2
(3,3-Difluoropyrrolidin-1-yl)(1H-pyrrol-2-yl)methanone chemical structure, C9H10F2N2O, CAS 2034299-12-0
(3,3-Difluoropyrrolidin-1-yl)(1H-pyrrol-2-yl)methanone
CAS 2034299-12-0C9H10F2N2O
(4-Bromo-1H-pyrrol-2-yl)(3,3-difluoropyrrolidin-1-yl)methanone chemical structure, C9H9BrF2N2O, CAS 1936175-53-9
(4-Bromo-1H-pyrrol-2-yl)(3,3-difluoropyrrolidin-1-yl)methanone
CAS 1936175-53-9C9H9BrF2N2O
2-Chloro-N-[5-(pyrrolidine-1-carbonyl)-1H-pyrrol-3-yl]acetamide chemical structure, C11H14ClN3O2, CAS 2249408-21-5
2-Chloro-N-[5-(pyrrolidine-1-carbonyl)-1H-pyrrol-3-yl]acetamide
CAS 2249408-21-5C11H14ClN3O2
5-(Pyrrolidine-1-carbonyl)-1H-pyrrole-3-sulfonyl fluoride chemical structure, C9H11FN2O3S, CAS 2138291-64-0
5-(Pyrrolidine-1-carbonyl)-1H-pyrrole-3-sulfonyl fluoride
CAS 2138291-64-0C9H11FN2O3S
Sodium 5-(pyrrolidine-1-carbonyl)-1H-pyrrole-3-sulfinate chemical structure, C9H11N2NaO3S, CAS 2138156-46-2
Sodium 5-(pyrrolidine-1-carbonyl)-1H-pyrrole-3-sulfinate
CAS 2138156-46-2C9H11N2NaO3S