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Murcko scaffold

4-(Phenylamino)quinolin-2(1H)-one scaffold

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
17
With full pages
4
Scaffold SMILES

O=c1cc(Nc2ccccc2)c2ccccc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Phenylamino)quinolin-2(1H)-one page
Murcko scaffold O=c1cc(Nc2ccccc2)c2ccccc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

2(1H)-Quinolinone, 7-chloro-4-((3-((ethylamino)methyl)-4-hydroxyphenyl)amino)- chemical structure, C18H18ClN3O2, CAS 102790-37-4
2(1H)-Quinolinone, 7-chloro-4-((3-((ethylamino)methyl)-4-hydroxyphenyl)amino)-
CAS 102790-37-4C18H18ClN3O2
4-(Phenylamino)quinolin-2(1H)-one chemical structure, C15H12N2O, CAS 6628-93-9
4-(Phenylamino)quinolin-2(1H)-one
CAS 6628-93-9C15H12N2O
4-Anilino-1-methyl-3-nitroquinolin-2(1H)-one chemical structure, C16H13N3O3, CAS 141945-56-4
4-Anilino-1-methyl-3-nitroquinolin-2(1H)-one
CAS 141945-56-4C16H13N3O3
4-((4-Methoxyphenyl)amino)-1-methyl-3-nitroquinolin-2(1H)-one chemical structure, C17H15N3O4, CAS 313276-30-1
4-((4-Methoxyphenyl)amino)-1-methyl-3-nitroquinolin-2(1H)-one
CAS 313276-30-1C17H15N3O4
4-(3-Methoxyanilino)-1-methyl-3-nitroquinolin-2-one chemical structure, C17H15N3O4, CAS 337338-53-1
4-(3-Methoxyanilino)-1-methyl-3-nitroquinolin-2-one
CAS 337338-53-1C17H15N3O4
4-(3,4-Dimethylanilino)-1-methyl-3-nitroquinolin-2-one chemical structure, C18H17N3O3, CAS 373611-73-5
4-(3,4-Dimethylanilino)-1-methyl-3-nitroquinolin-2-one
CAS 373611-73-5C18H17N3O3
3-Quinolinecarboxylic acid, 1,2-dihydro-1-methyl-4-((4-methylphenyl)amino)-2-oxo-, ethyl ester chemical structure, C20H20N2O3, CAS 75483-10-2
3-Quinolinecarboxylic acid, 1,2-dihydro-1-methyl-4-((4-methylphenyl)amino)-2-oxo-, ethyl ester
CAS 75483-10-2C20H20N2O3
3-Quinolinecarboxylic acid, 1,2-dihydro-4-((4-methoxyphenyl)amino)-1-methyl-2-oxo-, ethyl ester chemical structure, C20H20N2O4, CAS 75483-11-3
3-Quinolinecarboxylic acid, 1,2-dihydro-4-((4-methoxyphenyl)amino)-1-methyl-2-oxo-, ethyl ester
CAS 75483-11-3C20H20N2O4
3-Quinolinecarboxylic acid, 1,2-dihydro-4-((4-chlorophenyl)amino)-1-methyl-2-oxo-, ethyl ester chemical structure, C19H17ClN2O3, CAS 75483-12-4
3-Quinolinecarboxylic acid, 1,2-dihydro-4-((4-chlorophenyl)amino)-1-methyl-2-oxo-, ethyl ester
CAS 75483-12-4C19H17ClN2O3
3-Quinolinecarboxylic acid, 1,2-dihydro-1-methyl-2-oxo-4-((3-(trifluoromethyl)phenyl)amino)-, ethyl ester chemical structure, C20H17F3N2O3, CAS 75483-13-5
3-Quinolinecarboxylic acid, 1,2-dihydro-1-methyl-2-oxo-4-((3-(trifluoromethyl)phenyl)amino)-, ethyl ester
CAS 75483-13-5C20H17F3N2O3
4-(4-Chloroanilino)-1-methyl-3-nitro-2-quinolinone chemical structure, C16H12ClN3O3, CAS 309739-05-7
4-(4-Chloroanilino)-1-methyl-3-nitro-2-quinolinone
CAS 309739-05-7C16H12ClN3O3
N-[4-[(1-Methyl-3-nitro-2-oxoquinolin-4-yl)amino]phenyl]acetamide chemical structure, C18H16N4O4, CAS 372978-50-2
N-[4-[(1-Methyl-3-nitro-2-oxoquinolin-4-yl)amino]phenyl]acetamide
CAS 372978-50-2C18H16N4O4
N-(4-((1-Ethyl-3-nitro-2-oxo-1,2-dihydroquinolin-4-yl)amino)phenyl)acetamide chemical structure, C19H18N4O4, CAS 433324-23-3
N-(4-((1-Ethyl-3-nitro-2-oxo-1,2-dihydroquinolin-4-yl)amino)phenyl)acetamide
CAS 433324-23-3C19H18N4O4
4-((3-Acetylphenyl)amino)-1-methyl-3-nitroquinolin-2(1H)-one chemical structure, C18H15N3O4, CAS 849916-24-1
4-((3-Acetylphenyl)amino)-1-methyl-3-nitroquinolin-2(1H)-one
CAS 849916-24-1C18H15N3O4
4-((4-Isopropylphenyl)amino)-1-methyl-3-nitroquinolin-2(1H)-one chemical structure, C19H19N3O3, CAS 874463-51-1
4-((4-Isopropylphenyl)amino)-1-methyl-3-nitroquinolin-2(1H)-one
CAS 874463-51-1C19H19N3O3
4-(4-Methoxyanilino)quinolin-2(1H)-one chemical structure, C16H14N2O2, CAS 824935-58-2
4-(4-Methoxyanilino)quinolin-2(1H)-one
CAS 824935-58-2C16H14N2O2
6-Methyl-4-(phenylamino)quinolin-2(1H)-one chemical structure, C16H14N2O, CAS 1431867-35-4
6-Methyl-4-(phenylamino)quinolin-2(1H)-one
CAS 1431867-35-4C16H14N2O