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Murcko scaffold

Ring system with 2 rings and 15 atoms

27 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
27
With full pages
3
Scaffold SMILES

O=S(=O)(Nc1ccccc1)c1cnoc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1ccccc1)c1cnoc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

N-(4-Chlorophenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide chemical structure, C11H11ClN2O3S, CAS 80466-89-3
N-(4-Chlorophenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide
CAS 80466-89-3C11H11ClN2O3S
N-(4-{[(3,5-Dimethyl-4-isoxazolyl)sulfonyl]amino}phenyl)acetamide chemical structure, C13H15N3O4S, CAS 439934-45-9
N-(4-{[(3,5-Dimethyl-4-isoxazolyl)sulfonyl]amino}phenyl)acetamide
CAS 439934-45-9C13H15N3O4S
4-{[(3,5-Dimethylisoxazol-4-yl)sulfonyl]amino}benzoic acid chemical structure, C12H12N2O5S, CAS 888949-48-2
4-{[(3,5-Dimethylisoxazol-4-yl)sulfonyl]amino}benzoic acid
CAS 888949-48-2C12H12N2O5S
N-(3-Methoxyphenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide chemical structure, C12H14N2O4S, CAS 890168-89-5
N-(3-Methoxyphenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide
CAS 890168-89-5C12H14N2O4S
N-(4-Bromophenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide chemical structure, C11H11BrN2O3S, CAS 86321-35-9
N-(4-Bromophenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide
CAS 86321-35-9C11H11BrN2O3S
N-(4-Isopropyl-3-methylphenyl)-3,5-dimethyl-4-isoxazolesulfonamide chemical structure, C15H20N2O3S, CAS 866154-82-7
N-(4-Isopropyl-3-methylphenyl)-3,5-dimethyl-4-isoxazolesulfonamide
CAS 866154-82-7C15H20N2O3S
N-(3-Bromophenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide chemical structure, C11H11BrN2O3S, CAS 1042644-92-7
N-(3-Bromophenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide
CAS 1042644-92-7C11H11BrN2O3S
3,5-Dimethyl-N-[3-(trifluoromethyl)phenyl]-1,2-oxazole-4-sulfonamide chemical structure, C12H11F3N2O3S, CAS 874468-11-8
3,5-Dimethyl-N-[3-(trifluoromethyl)phenyl]-1,2-oxazole-4-sulfonamide
CAS 874468-11-8C12H11F3N2O3S
N-[3-Chloro-4-(difluoromethoxy)phenyl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide chemical structure, C12H11ClF2N2O4S, CAS 828277-49-2
N-[3-Chloro-4-(difluoromethoxy)phenyl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide
CAS 828277-49-2C12H11ClF2N2O4S
N-[2-(Difluoromethoxy)phenyl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide chemical structure, C12H12F2N2O4S, CAS 828277-67-4
N-[2-(Difluoromethoxy)phenyl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide
CAS 828277-67-4C12H12F2N2O4S
3,5-Dimethyl-N-(4-methylphenyl)-1,2-oxazole-4-sulfonamide chemical structure, C12H14N2O3S, CAS 878733-35-8
3,5-Dimethyl-N-(4-methylphenyl)-1,2-oxazole-4-sulfonamide
CAS 878733-35-8C12H14N2O3S
Methyl 4-{[(3,5-dimethylisoxazol-4-yl)sulfonyl]amino}benzoate chemical structure, C13H14N2O5S, CAS 890169-04-7
Methyl 4-{[(3,5-dimethylisoxazol-4-yl)sulfonyl]amino}benzoate
CAS 890169-04-7C13H14N2O5S
3,5-Dimethyl-N-[4-(trifluoromethoxy)phenyl]-1,2-oxazole-4-sulfonamide chemical structure, C12H11F3N2O4S, CAS 890169-00-3
3,5-Dimethyl-N-[4-(trifluoromethoxy)phenyl]-1,2-oxazole-4-sulfonamide
CAS 890169-00-3C12H11F3N2O4S
N-(4-Acetylphenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide chemical structure, C13H14N2O4S, CAS 438622-75-4
N-(4-Acetylphenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide
CAS 438622-75-4C13H14N2O4S
N-(4-Bromo-2-methylphenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide chemical structure, C12H13BrN2O3S, CAS 1042780-00-6
N-(4-Bromo-2-methylphenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide
CAS 1042780-00-6C12H13BrN2O3S
N-(3,4-Difluorophenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide chemical structure, C11H10F2N2O3S, CAS 942657-67-2
N-(3,4-Difluorophenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide
CAS 942657-67-2C11H10F2N2O3S
2-(3,5-Dimethylisoxazole-4-sulfonamido)benzoic acid chemical structure, C12H12N2O5S, CAS 1042769-63-0
2-(3,5-Dimethylisoxazole-4-sulfonamido)benzoic acid
CAS 1042769-63-0C12H12N2O5S
3,5-Dimethyl-N-(4-sulfamoylphenyl)-1,2-oxazole-4-sulfonamide chemical structure, C11H13N3O5S2, CAS 942688-37-1
3,5-Dimethyl-N-(4-sulfamoylphenyl)-1,2-oxazole-4-sulfonamide
CAS 942688-37-1C11H13N3O5S2
N-(2,4-Dichlorophenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide chemical structure, C11H10Cl2N2O3S, CAS 1219543-23-3
N-(2,4-Dichlorophenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide
CAS 1219543-23-3C11H10Cl2N2O3S
[(3,5-Dimethylisoxazol-4-yl)sulfonyl](4-hydroxyphenyl)amine chemical structure, C11H12N2O4S, CAS 1042783-93-6
[(3,5-Dimethylisoxazol-4-yl)sulfonyl](4-hydroxyphenyl)amine
CAS 1042783-93-6C11H12N2O4S
N-(3-Hydroxyphenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide chemical structure, C11H12N2O4S, CAS 1042784-21-3
N-(3-Hydroxyphenyl)-3,5-dimethyl-1,2-oxazole-4-sulfonamide
CAS 1042784-21-3C11H12N2O4S
5-(3,5-Dimethylisoxazole-4-sulfonamido)-2-hydroxybenzoic acid chemical structure, C12H12N2O6S, CAS 1039976-51-6
5-(3,5-Dimethylisoxazole-4-sulfonamido)-2-hydroxybenzoic acid
CAS 1039976-51-6C12H12N2O6S
2-(4-(3,5-Dimethylisoxazole-4-sulfonamido)phenyl)-N-(2-methoxyethyl)acetamide chemical structure, C16H21N3O5S, CAS 1207056-47-0
2-(4-(3,5-Dimethylisoxazole-4-sulfonamido)phenyl)-N-(2-methoxyethyl)acetamide
CAS 1207056-47-0C16H21N3O5S
3-{[(3,5-Dimethylisoxazol-4-yl)sulfonyl]amino}benzoic acid chemical structure, C12H12N2O5S, CAS 901253-51-8
3-{[(3,5-Dimethylisoxazol-4-yl)sulfonyl]amino}benzoic acid
CAS 901253-51-8C12H12N2O5S