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Murcko scaffold

3',4'-Dihydrospiro[imidazolidine-4,1'(2'H)-naphthalene]-2,5-dione scaffold

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
7
With full pages
5
Scaffold SMILES

O=C1NC(=O)C2(CCCc3ccccc32)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3',4'-Dihydrospiro[imidazolidine-4,1'(2'H)-naphthalene]-2,5-dione page
Murcko scaffold O=C1NC(=O)C2(CCCc3ccccc32)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

3',4'-Dihydrospiro[imidazolidine-4,1'(2'H)-naphthalene]-2,5-dione chemical structure, C12H12N2O2, CAS 57998-96-6
3',4'-Dihydrospiro[imidazolidine-4,1'(2'H)-naphthalene]-2,5-dione
CAS 57998-96-6C12H12N2O2
Spiro(imidazolidine-4,5-dione, 7'-[bis(2-chloroethyl)amino]-3,3',4'-dihydro- chemical structure, C16H19Cl2N3O2, CAS 5636-82-8
Spiro(imidazolidine-4,5-dione, 7'-[bis(2-chloroethyl)amino]-3,3',4'-dihydro-
CAS 5636-82-8C16H19Cl2N3O2
6'-Methoxy-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalene]-2,5-dione chemical structure, C13H14N2O3, CAS 30265-10-2
6'-Methoxy-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalene]-2,5-dione
CAS 30265-10-2C13H14N2O3
2-{2,5-Dioxo-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalene]-1-yl}acetic acid chemical structure, C14H14N2O4, CAS 851170-88-2
2-{2,5-Dioxo-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalene]-1-yl}acetic acid
CAS 851170-88-2C14H14N2O4
N-(1-Cyano-1,2-dimethylpropyl)-2-{2,5-dioxo-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalen]-1-YL}acetamide chemical structure, C20H24N4O3, CAS 923781-64-0
N-(1-Cyano-1,2-dimethylpropyl)-2-{2,5-dioxo-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalen]-1-YL}acetamide
CAS 923781-64-0C20H24N4O3
2-(2,5-Dioxo-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalen]-1-yl)acetonitrile chemical structure, C14H13N3O2, CAS 876556-09-1
2-(2,5-Dioxo-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalen]-1-yl)acetonitrile
CAS 876556-09-1C14H13N3O2
6'-Amino-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalene]-2,5-dione chemical structure, C12H13N3O2, CAS 2870673-24-6
6'-Amino-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalene]-2,5-dione
CAS 2870673-24-6C12H13N3O2