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Murcko scaffold

1,2-Dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one scaffold

26 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 15
Chemicals: 26
With full pages: 2

Scaffold SMILES

O=C1Nc2ccccc2C2(CCNC2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1,2-Dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one page

Murcko scaffold O=C1Nc2ccccc2C2(CCNC2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

tert-Butyl 2-oxo-1,2-dihydrospiro[benzo[D][1,3]oxazine-4,3'-pyrrolidine]-1'-carboxylate chemical structure, C16H20N2O4, CAS 1042700-93-5

tert-Butyl 2-oxo-1,2-dihydrospiro[benzo[D][1,3]oxazine-4,3'-pyrrolidine]-1'-carboxylate

CAS 1042700-93-5C₁₆H₂₀N₂O₄

tert-Butyl 6-chloro-2-oxospiro[1H-3,1-benzoxazine-4,3'-pyrrolidine]-1'-carboxylate chemical structure, C16H19ClN2O4, CAS 1042700-95-7

tert-Butyl 6-chloro-2-oxospiro[1H-3,1-benzoxazine-4,3'-pyrrolidine]-1'-carboxylate

CAS 1042700-95-7C₁₆H₁₉ClN₂O₄

1,2-Dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one chemical structure, C11H12N2O2, CAS 1896542-19-0

1,2-Dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one

CAS 1896542-19-0C₁₁H₁₂N₂O₂

6-Methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one chemical structure, C12H14N2O2, CAS 1821026-62-3

6-Methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one

CAS 1821026-62-3C₁₂H₁₄N₂O₂

6-Fluoro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one chemical structure, C11H11FN2O2, CAS 1890000-98-2

6-Fluoro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one

CAS 1890000-98-2C₁₁H₁₁FN₂O₂

6-Chloro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one chemical structure, C11H11ClN2O2, CAS 1821028-98-1

6-Chloro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one

CAS 1821028-98-1C₁₁H₁₁ClN₂O₂

6-Bromo-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one chemical structure, C11H11BrN2O2, CAS 1890728-67-2

6-Bromo-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one

CAS 1890728-67-2C₁₁H₁₁BrN₂O₂

6-Methoxy-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one chemical structure, C12H14N2O3, CAS 1894667-05-0

6-Methoxy-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one

CAS 1894667-05-0C₁₂H₁₄N₂O₃

7-Chloro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one chemical structure, C11H11ClN2O2, CAS 1894667-09-4

7-Chloro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one

CAS 1894667-09-4C₁₁H₁₁ClN₂O₂

8-Methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one chemical structure, C12H14N2O2, CAS 1894722-92-9

8-Methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one

CAS 1894722-92-9C₁₂H₁₄N₂O₂

8-Fluoro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one chemical structure, C11H11FN2O2, CAS 1892807-43-0

8-Fluoro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one

CAS 1892807-43-0C₁₁H₁₁FN₂O₂

8-Chloro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one chemical structure, C11H11ClN2O2, CAS 1894022-70-8

8-Chloro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one

CAS 1894022-70-8C₁₁H₁₁ClN₂O₂

6-Chlorospiro[benzo[D][1,3]oxazine-4,3'-pyrrolidin]-2(1H)-one hydrochloride chemical structure, C11H12Cl2N2O2, CAS 1821028-99-2

6-Chlorospiro[benzo[D][1,3]oxazine-4,3'-pyrrolidin]-2(1H)-one hydrochloride

CAS 1821028-99-2C₁₁H₁₂Cl₂N₂O₂

(R)-6-Chloro-5-fluorospiro[benzo[d][1,3]oxazine-4,3'-pyrrolidin]-2(1H)-one chemical structure, C11H10ClFN2O2, CAS 2857081-38-8

(R)-6-Chloro-5-fluorospiro[benzo[d][1,3]oxazine-4,3'-pyrrolidin]-2(1H)-one

CAS 2857081-38-8C₁₁H₁₀ClFN₂O₂

6-Methyl-1,2-dihydrospiro(3,1-benzoxazine-4,3'-pyrrolidin)-2-one, trifluoroacetic acid chemical structure, C14H15F3N2O4, CAS 2361644-56-4

6-Methyl-1,2-dihydrospiro(3,1-benzoxazine-4,3'-pyrrolidin)-2-one, trifluoroacetic acid

CAS 2361644-56-4C₁₄H₁₅F₃N₂O₄

6-Chloro-1,2-dihydrospiro(3,1-benzoxazine-4,3'-pyrrolidine)-2-one, trifluoroacetic acid chemical structure, C13H12ClF3N2O4, CAS 2361645-76-1

6-Chloro-1,2-dihydrospiro(3,1-benzoxazine-4,3'-pyrrolidine)-2-one, trifluoroacetic acid

CAS 2361645-76-1C₁₃H₁₂ClF₃N₂O₄

6-Methoxyspiro[1H-3,1-benzoxazine-4,3'-pyrrolidine]-2-one, hydrochloride chemical structure, C12H15ClN2O3, CAS 2361644-07-5

6-Methoxyspiro[1H-3,1-benzoxazine-4,3'-pyrrolidine]-2-one, hydrochloride

CAS 2361644-07-5C₁₂H₁₅ClN₂O₃

8-Chloro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidine]-2-one,trifluoroaceticacid chemical structure, C13H12ClF3N2O4, CAS 2361636-24-8

8-Chloro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidine]-2-one,trifluoroaceticacid

CAS 2361636-24-8C₁₃H₁₂ClF₃N₂O₄

8-Fluorospiro[1H-3,1-benzoxazine-4,3'-pyrrolidine]-2-one, 2,2,2-trifluoroacetic acid chemical structure, C13H12F4N2O4, CAS 2361645-60-3

8-Fluorospiro[1H-3,1-benzoxazine-4,3'-pyrrolidine]-2-one, 2,2,2-trifluoroacetic acid

CAS 2361645-60-3C₁₃H₁₂F₄N₂O₄

1,2-Dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one hydrochloride chemical structure, C11H13ClN2O2, CAS 2361802-65-3

1,2-Dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidin]-2-one hydrochloride

CAS 2361802-65-3C₁₁H₁₃ClN₂O₂

7-Methoxy-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidine]-2-one hydrochloride chemical structure, C12H15ClN2O3, CAS 2361711-07-9

7-Methoxy-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidine]-2-one hydrochloride

CAS 2361711-07-9C₁₂H₁₅ClN₂O₃

(S)-6-Chloro-5-fluorospiro[benzo[d][1,3]oxazine-4,3'-pyrrolidin]-2(1H)-one chemical structure, C11H10ClFN2O2, CAS 2839473-62-8

(S)-6-Chloro-5-fluorospiro[benzo[d][1,3]oxazine-4,3'-pyrrolidin]-2(1H)-one

CAS 2839473-62-8C₁₁H₁₀ClFN₂O₂

6-Fluorospiro[benzo[D][1,3]oxazine-4,3'-pyrrolidin]-2(1H)-one hydrochloride chemical structure, C11H12ClFN2O2, CAS 2361645-46-5

6-Fluorospiro[benzo[D][1,3]oxazine-4,3'-pyrrolidin]-2(1H)-one hydrochloride

CAS 2361645-46-5C₁₁H₁₂ClFN₂O₂

7-Chloro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidine]-2-one, trifluoroacetic acid chemical structure, C13H12ClF3N2O4, CAS 2361644-89-3

7-Chloro-1,2-dihydrospiro[3,1-benzoxazine-4,3'-pyrrolidine]-2-one, trifluoroacetic acid

CAS 2361644-89-3C₁₃H₁₂ClF₃N₂O₄