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Murcko scaffold

2-(Phenylmethyl)pyridine scaffold

672 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
672
With full pages
109
Scaffold SMILES

c1ccc(Cc2ccccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Phenylmethyl)pyridine page
Murcko scaffold c1ccc(Cc2ccccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 672 chemicals

2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-methoxyphenyl)acetamide chemical structure, C15H12ClF3N2O2, CAS 400081-93-8
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-methoxyphenyl)acetamide
CAS 400081-93-8C15H12ClF3N2O2
2-(4-Chlorophenyl)-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(dimethylamino)methylene]acetamide chemical structure, C17H14Cl2F3N3O, CAS 338407-12-8
2-(4-Chlorophenyl)-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(dimethylamino)methylene]acetamide
CAS 338407-12-8C17H14Cl2F3N3O
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C15H9ClF6N2O, CAS 338407-32-2
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-[3-(trifluoromethyl)phenyl]acetamide
CAS 338407-32-2C15H9ClF6N2O
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(2,4-dichlorophenyl)acetonitrile chemical structure, C14H6Cl3F3N2, CAS 213994-21-9
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(2,4-dichlorophenyl)acetonitrile
CAS 213994-21-9C14H6Cl3F3N2
3-[4-[[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]phenoxy]-2-butanone chemical structure, C17H15ClF3NO2, CAS 338402-03-2
3-[4-[[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]phenoxy]-2-butanone
CAS 338402-03-2C17H15ClF3NO2
2-(4-Chlorophenyl)-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]acetamide chemical structure, C14H9Cl2F3N2O, CAS 213993-82-9
2-(4-Chlorophenyl)-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]acetamide
CAS 213993-82-9C14H9Cl2F3N2O
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(2,6-dichlorophenyl)acetamide chemical structure, C14H8Cl3F3N2O, CAS 338407-72-0
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(2,6-dichlorophenyl)acetamide
CAS 338407-72-0C14H8Cl3F3N2O
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-phenylpentanedinitrile chemical structure, C17H11ClF3N3, CAS 339030-16-9
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-phenylpentanedinitrile
CAS 339030-16-9C17H11ClF3N3
4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]methyl}phenyl 2-propynyl ether chemical structure, C16H11ClF3NO, CAS 338402-02-1
4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]methyl}phenyl 2-propynyl ether
CAS 338402-02-1C16H11ClF3NO
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-phenylacetamide chemical structure, C14H10ClF3N2O, CAS 338406-87-4
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-phenylacetamide
CAS 338406-87-4C14H10ClF3N2O
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(3,4-dimethoxyphenyl)acetamide chemical structure, C16H14ClF3N2O3, CAS 338407-50-4
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(3,4-dimethoxyphenyl)acetamide
CAS 338407-50-4C16H14ClF3N2O3
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(dimethylamino)methylene]-2-phenylacetamide chemical structure, C17H15ClF3N3O, CAS 338406-89-6
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(dimethylamino)methylene]-2-phenylacetamide
CAS 338406-89-6C17H15ClF3N3O
4-[[3-Chloro-5-(trifluoromethyl)-2-pyridinyl](cyano)methyl]phenyl acetate chemical structure, C16H10ClF3N2O2, CAS 338410-39-2
4-[[3-Chloro-5-(trifluoromethyl)-2-pyridinyl](cyano)methyl]phenyl acetate
CAS 338410-39-2C16H10ClF3N2O2
4-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-nitriloethyl}phenyl methanesulfonate chemical structure, C15H10ClF3N2O3S, CAS 338410-42-7
4-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-nitriloethyl}phenyl methanesulfonate
CAS 338410-42-7C15H10ClF3N2O3S
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-[3-(trifluoromethyl)phenyl]acetonitrile chemical structure, C15H7ClF6N2, CAS 338407-22-0
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-[3-(trifluoromethyl)phenyl]acetonitrile
CAS 338407-22-0C15H7ClF6N2
[4-(Dimethylamino)phenyl](pyridin-2-yl)methanol chemical structure, C14H16N2O, CAS 109520-25-4
[4-(Dimethylamino)phenyl](pyridin-2-yl)methanol
CAS 109520-25-4C14H16N2O
2-(3-Chlorophenyl)-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]acetonitrile chemical structure, C14H7Cl2F3N2, CAS 213994-13-9
2-(3-Chlorophenyl)-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]acetonitrile
CAS 213994-13-9C14H7Cl2F3N2
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(2,4-dichlorophenyl)acetamide chemical structure, C14H8Cl3F3N2O, CAS 338407-80-0
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(2,4-dichlorophenyl)acetamide
CAS 338407-80-0C14H8Cl3F3N2O
2-[6-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-phenylacetonitrile chemical structure, C14H8ClF3N2, CAS 339010-55-8
2-[6-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-phenylacetonitrile
CAS 339010-55-8C14H8ClF3N2
[3-Chloro-5-(trifluoromethyl)-2-pyridinyl](4-methoxyphenyl)methanol chemical structure, C14H11ClF3NO2, CAS 321432-48-8
[3-Chloro-5-(trifluoromethyl)-2-pyridinyl](4-methoxyphenyl)methanol
CAS 321432-48-8C14H11ClF3NO2
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-methoxyphenyl)pentanedinitrile chemical structure, C18H13ClF3N3O, CAS 338397-59-4
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-methoxyphenyl)pentanedinitrile
CAS 338397-59-4C18H13ClF3N3O
Deschloro carbinoxamine chemical structure, C16H20N2O, CAS 1221-70-1
Deschloro carbinoxamine
CAS 1221-70-1C16H20N2O
(2-Methylphenyl)(2-pyridinyl)methanol chemical structure, C13H13NO, CAS 54941-74-1
(2-Methylphenyl)(2-pyridinyl)methanol
CAS 54941-74-1C13H13NO
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-phenylethanethioamide chemical structure, C14H10ClF3N2S, CAS 339104-34-6
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-phenylethanethioamide
CAS 339104-34-6C14H10ClF3N2S